Represents the grant date fair value of options granted during the reporting period.

No definition available.

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Total number of common shares of an entity that have been sold or granted to shareholders (includes common shares that were issued, repurchased and remain in the treasury). These shares represent capital invested by the firm's shareholders and owners, and may be all or only a portion of the number of shares authorized. Shares issued include shares outstanding and shares held in the treasury.

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Period over which grantee's right to exercise award under share-based payment arrangement is no longer contingent on satisfaction of service or performance condition, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. Includes, but is not limited to, combination of market, performance or service condition.

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The number of grants made during the period on other than stock (or unit) option plans (for example, phantom stock or unit plan, stock or unit appreciation rights plan, performance target plan).

+ References

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The number of non-vested equity-based payment instruments, excluding stock (or unit) options, that validly exist and are outstanding as of the balance sheet date.

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Per share or unit weighted-average fair value of nonvested award under share-based payment arrangement. Excludes share and unit options.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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No definition available.

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Number of additional shares authorized for issuance under share-based payment arrangement.

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No definition available.

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Number of shares authorized for issuance under share-based payment arrangement.

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The difference between the maximum number of shares (or other type of equity) authorized for issuance under the plan (including the effects of amendments and adjustments), and the sum of: 1) the number of shares (or other type of equity) already issued upon exercise of options or other equity-based awards under the plan; and 2) shares (or other type of equity) reserved for issuance on granting of outstanding awards, net of cancellations and forfeitures, if applicable.

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Gross number of share options (or share units) granted during the period.

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No definition available.

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Period from grant date that an equity-based award expires, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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Number of shares related to Restricted Stock Award forfeited during the period.

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Number of share options (or share units) exercised during the current period.

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Stock Based Compensation - Narrative (Details) - $ / shares		3 Months Ended		12 Months Ended
	Apr. 25, 2022	Mar. 31, 2022	Mar. 31, 2021	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019	Oct. 31, 2020
Stock-based compensation
Common stock, shares issued		9,993,135		9,993,135
Options granted (in shares)		265,000	73,669
Options exercised (in shares)		0	0
Minimum
Stock-based compensation
Stock awards vesting period		1 year
Options granted, grant date fair value		$ 2.62	$ 5.40
Maximum
Stock-based compensation
Stock awards vesting period		4 years
Options granted, grant date fair value		$ 2.90	$ 6.14
Stock options
Stock-based compensation
Options granted (in shares)		265,000
Options exercised (in shares)		0
Restricted Stock Units (RSUs) [Member]
Stock-based compensation
Restricted Stock Units, Granted		0		18,992	3,938	14,000
Stock units forfeited					1,491
Restricted Stock Units outstanding/unvested		18,992		18,992
Restricted stock units, grant date fair value		$ 6.69		$ 6.69
Restricted Stock Units (RSUs) [Member] \| Fulfillment of Certain Clinical Conditions [Member]
Stock-based compensation
Restricted Stock Units outstanding/unvested					16,524
Restricted Stock Units (RSUs) [Member] \| Minimum
Stock-based compensation
Stock awards vesting period				1 year
Restricted Stock Units (RSUs) [Member] \| Maximum
Stock-based compensation
Stock awards vesting period				3 years
2018 Equity Incentive Plan (the "2018 Plan") [Member]
Stock-based compensation
Number of shares reserved for issuance		260,794
Life of stock option awards granted		10 years
Number of authorized additional shares to be issued	500,000
2018 Equity Incentive Plan (the "2018 Plan") [Member] \| Minimum
Stock-based compensation
Stock awards vesting period		1 year
2018 Equity Incentive Plan (the "2018 Plan") [Member] \| Maximum
Stock-based compensation
Stock awards vesting period		4 years
Inducement Equity Incentive Plan 2020 [Member]
Stock-based compensation
Number of shares reserved for issuance		80,000
Number of authorized shares							200,000
Common stock, shares issued		120,000