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Stockholders Equity (Narrative) (Details) |  |  |  |  |  | 1 Months Ended | 12 Months Ended
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Aug. 15, 2022 USD ($) shares | Aug. 12, 2022 USD ($) shares | Aug. 12, 2021 USD ($) | Mar. 16, 2021 USD ($) | Mar. 12, 2021 $ / shares shares | Jul. 31, 2017 $ / shares shares | Dec. 31, 2022 USD ($) item $ / shares shares | Dec. 31, 2021 USD ($) $ / shares shares
Class of Stock [Line Items] |  |  |  |  |  |  |  |
Aggregate offering price | $ |  |  |  |  |  |  |  | $ 13,502,000
Common stock, par value (in dollars per share) | $ / shares |  |  |  |  |  |  | $ 0.001 | $ 0.001
Preferred stock, par value (in dollars per share) | $ / shares |  |  |  |  |  |  | $ 0.001 | $ 0.001
Common stock, shares outstanding (in shares) |  |  |  |  |  |  | 9,422,089 | 9,993,135
Warrant & stock option exercises (in shares) |  |  |  |  |  |  | 0 | 6,600
July 2017 - Underwritten Public Offering [Member] |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |
Warrant Exercises (in shares) |  |  |  |  |  |  |  | 909,000
Warrants, exercise price per share | $ / shares |  |  |  |  |  |  | $ 40.00 |
Percentage of outstanding common stock |  |  |  |  |  |  | 4.99% |
Outstanding common stock at election of purchaser |  |  |  |  |  |  | 9.99% |
Warrants outstanding |  |  |  |  |  |  | 374,525 |
Warrants exercised |  |  |  |  |  |  | 0 | 0
Common Stock |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |
Aggregate offering price | $ |  |  |  |  |  |  |  | $ 2,000
Number of shares issued (in shares) |  |  |  |  |  |  |  | 2,078,214
Warrant & stock option exercises (in shares) |  |  |  |  |  |  |  | 915,600
Cantor Fitzgerald & Co. [Member] |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |
Aggregate offering price | $ |  |  | $ 50,000,000.0 |  |  |  |  |
Number of share sold under the sales agreement | 3,281,067 |  |  |  |  |  | 2,528,642 |
Proceeds from issuance of common stock, gross | $ | $ 7,600,000 |  |  |  |  |  | $ 3,400,000 |
Cantor Fitzgerald & Co. [Member] | August 2021 Controlled Equity Offering Sales Agreement [Member] |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |
Number of share sold under the sales agreement |  | 1,987,100 |  |  |  |  |  |
Total gross proceeds received | $ |  | $ 2,721,187 |  |  |  |  |  |
Acorn Bioventures, LP [Member] |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |
Warrants to purchase shares |  |  |  |  |  |  | 669,854 |
Warrant outstanding Term |  |  |  |  |  |  | 5 years |
Warrants, exercise price per share | $ / shares |  |  |  |  |  |  | $ 4.13 |
Warrants exercised |  |  |  |  |  |  | 0 | 0
Co-Placement Agents [Member] |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |
Warrants, exercise price per share | $ / shares |  |  |  |  |  |  | $ 5.00 |
Number of warrant to purchase each share of our common stock |  |  |  |  |  |  | 1 |
Warrants outstanding |  |  |  |  |  |  | 2,190,000 |
Fractional shares issued |  |  |  |  |  |  | 0 |
Co-Placement Agents [Member] | Common Stock Warrants |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |
Percentage of outstanding common stock |  |  |  |  |  |  | 4.99% |
Outstanding common stock at election of purchaser |  |  |  |  |  |  | 9.99% |
Notice period from the holder to increase the percentage of ownership of outstanding common stock after exercise of warrants |  |  |  |  |  |  | 61 days |
Oppenheimer & Co. Inc. [Member] | March 2021 Equity Financing [Member] |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |
Common stock, par value (in dollars per share) | $ / shares |  |  |  |  | $ 0.001 |  |  |
Number of share sold under the sales agreement |  |  |  |  | 1,807,143 |  |  |
Sale of stock, number of additional shares issued in transaction |  |  |  |  | 271,071 |  |  |
Proceeds from issuance of common stock, net of issuance costs | $ |  |  |  | $ 13,500,000 |  |  |  |
Share issue price per share | $ / shares |  |  |  |  | $ 7.00 |  |  |
6% convertible exchangeable preferred stock |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |
Preferred stock, shares issued |  |  |  |  |  |  | 335,273 | 335,273
Preferred stock, shares outstanding |  |  |  |  |  |  | 335,273 | 335,273
Share issue price per share | $ / shares |  |  |  |  |  |  | $ 10.00 |
Number of common shares issued upon conversion |  |  |  |  |  |  | 0.00025 |
Share Price | $ / shares |  |  |  |  |  |  | $ 59,220 |
Dividend rate on convertible exchangeable preferred stock (in percent) |  |  |  |  |  |  | 6.00% | 6.00%
Liquidation preference (in dollars per share) | $ / shares |  |  |  |  |  |  | $ 10.00 |
Accrued and unpaid dividends in arrears on preferred stock | $ |  |  |  |  |  |  | $ 700,000 |
Accrued and unpaid dividends in arrears on preferred stock (in dollars per share) | $ / shares |  |  |  |  |  |  | $ 1.95 |
Shares reserved for future issuance upon conversion |  |  |  |  |  |  | 85 |
Conversion price (in dollars per share) | $ / shares |  |  |  |  |  |  | $ 39,480 |
Percentage of closing sales price of common stock that conversion price must exceed in order for preferred stock to be convertible |  |  |  |  |  |  | 150.00% |
Number of trading days within 30 trading days in which the closing price of common stock must exceed conversion price for preferred stock to be convertible |  |  |  |  |  |  | 20 days |
Number of trading days during which closing price of common stock must exceed conversion price for at least 20 days in order for the preferred stock to be convertible |  |  |  |  |  |  | 30 days |
Number of trading days prior to notice of automatic conversion |  |  |  |  |  |  | 5 days |
Number of quarterly periods in which dividends are not paid that triggers the right of preferred stock holders to nominate and elect directors | item |  |  |  |  |  |  | 6 |
Interest rate of Convertible Subordinated Debentures (as a percent) |  |  |  |  |  |  | 6.00% |
Redemption price per share (in dollars per share) | $ / shares |  |  |  |  |  |  | $ 10.00 |
Debt principal amount per share, basis for exchange (in dollars per share) | $ / shares |  |  |  |  |  |  | $ 10.00 |
Debt instrument, term |  |  |  |  |  |  | 25 years |
Series A Convertible Preferred Stock |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |
Preferred stock, par value (in dollars per share) | $ / shares |  |  |  |  |  |  | $ 0.001 | $ 0.001
Preferred stock, shares issued |  |  |  |  |  | 8,872 | 264 | 264
Preferred stock, shares outstanding |  |  |  |  |  |  | 264 | 264
Number of shares converted |  |  |  |  |  |  | 6,600 |
Price per share used to determine number of shares of common stock | $ / shares |  |  |  |  |  | $ 1,000 |  |
Conversion price of convertible preferred stock | $ / shares |  |  |  |  |  | $ 40.00 |  |
Conversion percentage |  |  |  |  |  | 9.99% |  |
Measurement period of consecutive trading days used in determining whether specified triggers are met which would allow the entity to require the conversion of all or part of outstanding preferred stock |  |  |  |  |  |  | 30 days |
Percentage of blocker provision |  |  |  |  |  | 4.99% |  |
Series A Convertible Preferred Stock | Minimum |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |
Percentage by which the weighted average price of common stock during the measurement period exceeds the initial conversion price which triggers the right of the entity to cause all or part of the outstanding preferred stock to be converted |  |  |  |  |  |  | 300.00% |
Threshold amount of daily trading volume on each trading day during the measurement period which triggers the right of the entity to cause all or part of the outstanding preferred stock to be converted | $ |  |  |  |  |  |  | $ 500,000 |
Series B Convertible Preferred Stock |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |
Preferred stock, par value (in dollars per share) | $ / shares |  |  |  |  |  |  | $ 0.001 | $ 0.001
Preferred stock, shares issued |  |  |  |  |  |  | 237,745 | 237,745
Preferred stock, shares outstanding |  |  |  |  |  |  | 237,745 | 237,745
Outstanding common stock at election of purchaser |  |  |  |  |  |  | 9.99% |
Number of shares converted |  |  |  |  |  |  | 5 |

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