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Stockholders Equity (Narrative) (Details)
 1 Months Ended 12 Months Ended 24 Months Ended
Dec. 21, 2023
USD ($)
$ / shares
shares
Aug. 15, 2022
USD ($)
shares
Aug. 12, 2022
USD ($)
shares
Aug. 12, 2021
USD ($)
Dec. 31, 2020
shares
Jul. 31, 2017
$ / shares
shares
Dec. 31, 2023
USD ($)
item
$ / shares
shares
Dec. 31, 2022
$ / shares
shares
Dec. 31, 2023
$ / shares
shares
Dec. 26, 2023
USD ($)
Class of Stock [Line Items]                    
Common stock, par value (in dollars per share) | $ / shares             $ 0.001 $ 0.001 $ 0.001  
Common stock, shares authorized             100,000,000 100,000,000 100,000,000  
July 2017 - Underwritten Public Offering [Member]                    
Class of Stock [Line Items]                    
Warrants, exercise price per share | $ / shares             $ 600   $ 600  
Percentage of outstanding common stock             4.99%      
Outstanding common stock at election of purchaser             9.99%      
Warrants outstanding             24,968   24,968  
Warrants exercised             0   0  
December 2023 Insider Private Placement                    
Class of Stock [Line Items]                    
Share issue price per share | $ / shares $ 3.315                  
December 2023 Placement Agency Agreement                    
Class of Stock [Line Items]                    
Cash placement fee, percentage of gross proceeds raised 8.00%                  
Common Stock Warrants | December 2023 Private Placement                    
Class of Stock [Line Items]                    
Warrants to purchase shares 388,200                  
Warrant outstanding Term 7 years                  
Warrants, exercise price per share | $ / shares $ 3.19                  
Total gross proceeds received | $                   $ 1,000,000.0
Common Stock Warrants | December 2023 Insider Private Placement | Chief Executive Officer                    
Class of Stock [Line Items]                    
Warrants to purchase shares 6,070                  
Common Stock Warrants | December 2023 Insider Private Placement | Chief Financial Officer and Chief Operating Officer                    
Class of Stock [Line Items]                    
Warrants to purchase shares 1,886                  
Pre-Funded Warrants | December 2023 Securities Purchase Agreement                    
Class of Stock [Line Items]                    
Warrants to purchase shares 219,700                  
Warrants, exercise price per share | $ / shares $ 0.001                  
Share issue price per share | $ / shares $ 3.314                  
Placement Agent Warrants | December 2023 Placement Agency Agreement                    
Class of Stock [Line Items]                    
Warrants to purchase shares 23,769                  
Warrants, exercise price per share | $ / shares $ 4.14375                  
Percentage of outstanding common stock 6.00%                  
Maximum | December 2023 Placement Agency Agreement                    
Class of Stock [Line Items]                    
Placement agent fees | $ $ 85,000                  
Cantor Fitzgerald & Co. [Member]                    
Class of Stock [Line Items]                    
Aggregate offering price | $       $ 50,000,000.0            
Number of share sold under the sales agreement   218,738                
Proceeds from issuance of common stock, gross | $   $ 7,600,000                
Cantor Fitzgerald & Co. [Member] | August 2021 Controlled Equity Offering Sales Agreement [Member]                    
Class of Stock [Line Items]                    
Number of share sold under the sales agreement     132,473              
Aggregate purchase price | $     $ 4,494,496              
Total gross proceeds received | $     $ 2,721,187              
Reclassified shares     207,807              
Reclassified shares for which no proceeds were received     75,333              
Acorn Bioventures, LP [Member]                    
Class of Stock [Line Items]                    
Warrants to purchase shares             44,657   44,657  
Warrant outstanding Term             5 years   5 years  
Warrants, exercise price per share | $ / shares             $ 61.95   $ 61.95  
Number of warrants lapsing during period             15,833      
Warrants exercised               0    
Co-Placement Agents [Member]                    
Class of Stock [Line Items]                    
Warrants, exercise price per share | $ / shares             $ 75.00   $ 75.00  
Number of warrant to purchase each share of our common stock             1   1  
Warrants outstanding             146,000   146,000  
Fractional shares issued             0      
Co-Placement Agents [Member] | Common Stock Warrants                    
Class of Stock [Line Items]                    
Percentage of outstanding common stock             4.99%      
Outstanding common stock at election of purchaser             9.99%      
Notice period from the holder to increase the percentage of ownership of outstanding common stock after exercise of warrants             61 days      
6% convertible exchangeable preferred stock                    
Class of Stock [Line Items]                    
Preferred stock, shares issued             335,273 335,273 335,273  
Preferred stock, shares outstanding             335,273 335,273 335,273  
Share issue price per share | $ / shares             $ 10.00   $ 10.00  
Number of common shares issued upon conversion             0.0000167   0.0000167  
Share Price | $ / shares             $ 888,300   $ 888,300  
Dividend rate on convertible exchangeable preferred stock (in percent)             6.00% 6.00%    
Liquidation preference (in dollars per share) | $ / shares             $ 10.00   $ 10.00  
Accrued and unpaid dividends in arrears on preferred stock | $             $ 700,000      
Accrued and unpaid dividends in arrears on preferred stock (in dollars per share) | $ / shares             $ 1.95      
Shares reserved for future issuance upon conversion             6   6  
Conversion price (in dollars per share) | $ / shares             $ 592,200      
Percentage of closing sales price of common stock that conversion price must exceed in order for preferred stock to be convertible             150.00%      
Number of trading days within 30 trading days in which the closing price of common stock must exceed conversion price for preferred stock to be convertible             20 days      
Number of trading days during which closing price of common stock must exceed conversion price for at least 20 days in order for the preferred stock to be convertible             30 days      
Number of trading days prior to notice of automatic conversion             5 days      
Number of quarterly periods in which dividends are not paid that triggers the right of preferred stock holders to nominate and elect directors | item             6      
Interest rate of Convertible Subordinated Debentures (as a percent)             6.00%   6.00%  
Redemption price per share (in dollars per share) | $ / shares             $ 10.00   $ 10.00  
Debt principal amount per share, basis for exchange (in dollars per share) | $ / shares             $ 10.00      
Debt instrument, term             25 years      
Series A Convertible Preferred Stock                    
Class of Stock [Line Items]                    
Preferred stock, shares issued           8,872 264 264 264  
Preferred stock, shares outstanding             264 264 264  
Number of shares converted             440      
Price per share used to determine number of shares of common stock | $ / shares           $ 1,000        
Conversion price of convertible preferred stock | $ / shares           $ 600.00        
Conversion percentage           9.99%        
Measurement period of consecutive trading days used in determining whether specified triggers are met which would allow the entity to require the conversion of all or part of outstanding preferred stock             30 days      
Percentage of blocker provision           4.99%        
Series A Convertible Preferred Stock | Minimum                    
Class of Stock [Line Items]                    
Percentage by which the weighted average price of common stock during the measurement period exceeds the initial conversion price which triggers the right of the entity to cause all or part of the outstanding preferred stock to be converted             300.00%      
Threshold amount of daily trading volume on each trading day during the measurement period which triggers the right of the entity to cause all or part of the outstanding preferred stock to be converted | $             $ 500,000      
Series B Convertible Preferred Stock                    
Class of Stock [Line Items]                    
Preferred stock, shares issued             119,000 237,745 119,000  
Preferred stock, shares outstanding             119,000 237,745 119,000  
Number of share sold under the sales agreement         237,745          
Outstanding common stock at election of purchaser             9.99%      
Number of common shares issued upon conversion             39,582   39,582  
Number of shares converted             118,745      
Shares reserved for future issuance upon conversion             39,667   39,667  
Common Stock | December 2023 Securities Purchase Agreement                    
Class of Stock [Line Items]                    
Common stock, par value (in dollars per share) | $ / shares $ 0.001                  
Share issue price per share | $ / shares $ 3.315                  
Common stock, shares authorized 168,500                  
Common Stock | December 2023 Insider Private Placement | Chief Executive Officer                    
Class of Stock [Line Items]                    
Common stock, shares authorized 6,070                  
Common Stock | December 2023 Insider Private Placement | Chief Financial Officer and Chief Operating Officer                    
Class of Stock [Line Items]                    
Common stock, shares authorized 1,886