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Stock-Based Compensation (Tables)

6 Months Ended

Jun. 30, 2024

Stock-Based Compensation

Schedule of Stock Based Compensation Expense

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Three Months Ended

Six Months Ended

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June 30,

June 30,

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2024

2023

2024

2023

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General and administrative

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$

168

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$

243

​

$

321

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$

522

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Research and development

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​

21

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$

116

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​

71

​

​

238

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Stock-based compensation costs

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$

189

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$

359

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$

392

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$

760

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Schedule of Fair Value of the Stock Options Granted

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​	​	Six months ended	​	Six months ended
​		June 30, 2024		June 30, 2023
Expected term (years)		6		5 - 6
Risk free interest rate		3.995%	​	3.660%  – 4.050%
Volatility		93%	​	89% – 92%
Expected dividend yield over expected term		0.00%	​	0.00%
Resulting weighted average grant date fair value		$1.77	​	$6.63

Schedule of Share Option Activity

A summary of the share option activity and related information is as follows:

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​		​		​	​		Weighted		​	​
​		​		Weighted			Average		​	​
​		Number of		Average			Remaining		Aggregate
​	​	Options		Exercise			Contractual	​	Intrinsic
​	​	Outstanding	​	Price Per Share			Term (Years)	​	Value ($000)
Options outstanding at December 31, 2023		142,796	​	$	50.20		7.96	​	$	—
Granted	​	12,500	​	$	2.28		—	​	$	—
Exercised	​	—	​	$	—		—	​	$	—
Cancelled/forfeited	​	(23,552)	​	$	47.39		—	​	$	—
Options outstanding at June 30, 2024		131,744	​	$	46.16		7.32	​	$	—
​	​	​	​	​	​	​	​	​	​	​
Unvested at June 30, 2024		27,377	​	$	16.51		8.72	​	$	—
Vested and exercisable at June 30, 2024		104,367	​	$	53.94		6.95	​	$	—

Schedule of Restricted Stock Units Activity

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​	​	​	​	​	​	​	​
​		​		Weighted		​	Weighted
​		​		Average		​	Average
​	​	Restricted		Grant Date		​	Remaining
​	​	Stock Units	​	Value Per Share		​	Term
Restricted Stock Units outstanding at December 31, 2023		34,498	​	$	16.26	​	8.96 years
Granted	​	12,500	​	​	2.28	​	​
Cancelled/forfeited	​	(6,072)	​	​	15.76	​	​
Restricted Stock Units outstanding at June 30, 2024	​	40,926	​	$	12.07	​	8.80 years
​	​	​	​	​	​	​	​
Unvested at June 30, 2024		13,531	​	$	11.90	​	8.71 years
​	​	​	​	​	​	​	​
Vested at June 30, 2024		27,396	​	$	12.15	​	8.84 years

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