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Stock-Based Compensation (Tables)

9 Months Ended

Sep. 30, 2024

Stock-Based Compensation

Schedule of Stock Based Compensation Expense

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Three Months Ended

Nine Months Ended

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September 30,

September 30,

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2024

2023

2024

2023

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General and administrative

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$

101

​

$

279

​

$

421

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$

801

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Research and development

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​

6

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$

111

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​

78

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​

350

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Stock-based compensation costs

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$

107

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$

390

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$

499

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$

1,151

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Schedule of Fair Value of the Stock Options Granted

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​	​	Nine months ended	​	Nine months ended
​		September 30, 2024		September 30, 2023
Expected term (years)		6		5 - 6
Risk free interest rate		3.995%	​	3.660%  – 4.050%
Volatility		93%	​	89% – 92%
Expected dividend yield over expected term		0.00%	​	0.00%
Resulting weighted average grant date fair value		$1.77	​	$6.63

Schedule of Share Option Activity

A summary of the share option activity and related information is as follows:

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​		​		​	​		Weighted		​	​
​		​		Weighted			Average		​	​
​		Number of		Average			Remaining		Aggregate
​	​	Options		Exercise			Contractual	​	Intrinsic
​	​	Outstanding	​	Price Per Share			Term (Years)	​	Value ($000)
Options outstanding at December 31, 2023		142,796	​	$	50.20		7.96	​	$	—
Granted	​	12,500	​	$	2.28		—	​	$	—
Exercised	​	—	​	$	—		—	​	$	—
Cancelled/forfeited	​	(36,307)	​	$	51.78		—	​	$	—
Options outstanding at September 30, 2024		118,989	​	$	44.31		7.46	​	$	—
​	​	​	​	​	​	​	​	​	​	​
Unvested at September 30, 2024		20,273	​	$	14.00		8.53	​	$	—
Vested and exercisable at September 30, 2024		98,716	​	$	50.54		7.24	​	$	—

Schedule of Restricted Stock Units Activity

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​	​	​	​	​
​		​		Weighted
​		​		Average
​	​	Restricted		Remaining
​	​	Stock Units	​	Term
Restricted Stock Units outstanding at December 31, 2023		34,498	​	8.96 years
Granted	​	12,500	​	​
Cancelled/forfeited	​	(7,251)	​	​
Restricted Stock Units outstanding at September 30, 2024	​	39,747	​	8.55 years
​	​	​	​	​
Unvested at September 30, 2024		10,278	​	8.31 years
​	​	​	​	​
Vested at September 30, 2024		29,469	​	8.64 years

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