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Geographic and Segment Information | 12 Months Ended
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Dec. 31, 2024
Segment Reporting [Abstract] |
Geographic and Segment Information | 16. Geographic and Segment Information Geographic information for the years ended December 31, 2024 and 2023 is as follows (in thousands): Schedule of Geographic Information
|  | 2024 |  |  | 2023 |
|  | Year Ended December 31, |
|  | 2024 |  |  | 2023 |
Revenue |  |  |  |  |  |
United Kingdom |  | $ | 43 |  |  | $ | 420 |
Total Revenue |  | $ | 43 |  |  | $ | 420 |
Net loss |  |  |  |  |  |  |  |
United States |  | $ | (37 | ) |  | $ | (808 | )
United Kingdom |  |  | (11,175 | ) |  |  | (21,747 | )
Total Net Loss |  | $ | (11,212 | ) |  | $ | (22,555 | )
|  | 2024 |  |  | 2023 |
|  | December 31, |
|  | 2024 |  |  | 2023 |
Total Assets |  |  |  |  |  |  |  |
United States |  | $ | 3,285 |  |  | $ | 2,938 |
United Kingdom |  |  | 809 |  |  |  | 5,867 |
Total Assets |  | $ | 4,094 |  |  | $ | 8,805 |
Long Lived Assets, net |  |  |  |  |  |  |  |
United States |  | $ | 1 |  |  | $ | — |
United Kingdom |  |  | 2 |  |  |  | 9 |
Total Long Lived Assets, net |  | $ | 3 |  |  | $ | 9 |
The Company operates as a single 1 segment engaged in the development of innovative cancer medicines based on cell cycle, transcriptional regulation and mitosis control biology. Consistent with our operational structure, our Chief Executive Officer (CEO), as the chief operating decision maker, makes resource allocation and business process decisions globally across our consolidated business. Managing and allocating resources at the consolidated level enables our CEO to assess the overall level of resources available and how to best deploy these resources across functions, and research and development projects in line with our overarching long-term corporate-wide strategic goals, rather than on a geographic or some other basis. Consistent with this decision-making process, our CEO considers consolidated net loss, which is our single segment’s principal measure of segment profit and loss, when evaluating performance and allocating company-wide resources. Significant expenses are amounts that are regularly provided to our CEO and included in consolidated net loss, our primary measure of our single segment’s profit or loss. Our CEO regularly reviews reported consolidated revenues, significant expenses and consolidated net loss, in addition to forecasted revenues, significant expenses and net loss amounts for future periods. A summary of our consolidated net loss for the years ended December 31, 2024 and 2023 is as follows, including the significant expenses provided to and regularly reviewed by our CEO: Schedule of Summary of Consolidated Net Loss
|  | 2024 |  |  | 2023 |
|  | December 31, |
|  | 2024 |  |  | 2023 |
Revenues |  | $ | 43 |  |  | $ | 420 |
Operating expenses: |  |  |  |  |  |  |  |
Research and development |  |  | 6,655 |  |  |  | 19,155 |
General and administrative |  |  | 5,392 |  |  |  | 6,718 |
Total operating expenses |  |  | 12,047 |  |  |  | 25,873 |
Operating loss |  |  | (12,004 | ) |  |  | (25,453 | )
Total other income (expense), net |  |  | 10 |  |  |  | (98 | )
Loss before taxes |  |  | (11,994 | ) |  |  | (25,551 | )
Income tax benefit |  |  | 782 |  |  |  | 2,996 |
Net loss |  | $ | (11,212 | ) |  | $ | (22,555 | )

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- Definition The entire disclosure for reporting segments including data and tables. Reportable segments include those that meet any of the following quantitative thresholds a) it's reported revenue, including sales to external customers and intersegment sales or transfers is 10 percent or more of the combined revenue, internal and external, of all operating segments b) the absolute amount of its reported profit or loss is 10 percent or more of the greater, in absolute amount of 1) the combined reported profit of all operating segments that did not report a loss or 2) the combined reported loss of all operating segments that did report a loss c) its assets are 10 percent or more of the combined assets of all operating segments. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 21 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-21 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name 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