    <SEC-DOCUMENT>0001641172-25-021049-index.html : 20250725
    <SEC-HEADER>0001641172-25-021049.hdr.sgml : 20250725
    <ACCEPTANCE-DATETIME>20250725171346
    ACCESSION NUMBER:		0001641172-25-021049
    CONFORMED SUBMISSION TYPE:	424B3
    PUBLIC DOCUMENT COUNT:		30
    FILED AS OF DATE:		20250725
    DATE AS OF CHANGE:		20250725

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Cyclacel Pharmaceuticals, Inc.
    		CENTRAL INDEX KEY:			0001130166
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		ORGANIZATION NAME:           	03 Life Sciences
    		EIN:				911766850
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		424B3
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	333-288912
    		FILM NUMBER:		251152399

    	BUSINESS ADDRESS:
    		STREET 1:		200 CONNELL DRIVE
    		STREET 2:		SUITE 1500
    		CITY:			BERKELEY HEIGHTS
    		STATE:			NJ
    		ZIP:			07922
    		BUSINESS PHONE:		908-517-7330

    	MAIL ADDRESS:
    		STREET 1:		200 CONNELL DRIVE
    		STREET 2:		SUITE 1500
    		CITY:			BERKELEY HEIGHTS
    		STATE:			NJ
    		ZIP:			07922

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	XCYTE THERAPIES INC
    		DATE OF NAME CHANGE:	20001218
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>424B3
    <SEQUENCE>1
    <FILENAME>form424b3.htm
    <DESCRIPTION>424B3
    <TEXT>
    Document 1 - file: form424b3.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>forms-4_001.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: forms-4_001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>forms-4_002.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: forms-4_002.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>forms-4_003.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: forms-4_003.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>forms-4_004.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: forms-4_004.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>forms-4_005.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 6 - file: forms-4_005.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>forms-4_006.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 7 - file: forms-4_006.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>forms-4_007.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 8 - file: forms-4_007.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>forms-4_008.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 9 - file: forms-4_008.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>forms-4_009.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 10 - file: forms-4_009.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>forms-4_010.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 11 - file: forms-4_010.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>forms-4_011.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 12 - file: forms-4_011.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>13
    <FILENAME>forms-4_012.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 13 - file: forms-4_012.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>14
    <FILENAME>forms-4_013.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 14 - file: forms-4_013.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>15
    <FILENAME>forms-4_014.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 15 - file: forms-4_014.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>16
    <FILENAME>forms-4_015.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 16 - file: forms-4_015.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>17
    <FILENAME>forms-4_016.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 17 - file: forms-4_016.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>18
    <FILENAME>forms-4_017.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 18 - file: forms-4_017.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>19
    <FILENAME>forms-4_018.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 19 - file: forms-4_018.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>20
    <FILENAME>forms-4_019.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 20 - file: forms-4_019.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>21
    <FILENAME>forms-4_020.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 21 - file: forms-4_020.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>22
    <FILENAME>forms-4_021.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 22 - file: forms-4_021.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>23
    <FILENAME>forms-4_022.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 23 - file: forms-4_022.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>24
    <FILENAME>forms-4_023.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 24 - file: forms-4_023.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>25
    <FILENAME>aud_001.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 25 - file: aud_001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>26
    <FILENAME>forms-4_024.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 26 - file: forms-4_024.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>27
    <FILENAME>annexc_001.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 27 - file: annexc_001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>28
    <FILENAME>annexc_002.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 28 - file: annexc_002.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>29
    <FILENAME>annexc_003.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 29 - file: annexc_003.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>30
    <FILENAME>annexc_004.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 30 - file: annexc_004.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>