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Note 10 - Commitments and Contingencies (Details Textual) $ in Thousands |  | 12 Months Ended |
--- | --- | --- | ---
Jan. 22, 2021 shares | Dec. 31, 2021 ft² shares | Dec. 31, 2020 USD ($) | Apr. 16, 2020
Class of Warrant or Right, Issued During Period (in shares) |  | 15,000 |  |
TLF Bio Innovation, Related Party Warrants [Member] |  |  |  |
Class of Warrant or Right, Issued During Period (in shares) | 15,000 |  |  |
Warrants in Connection with Microprofit Agreement [Member] |  |  |  |
Class of Warrant or Right, Number of Securities Callable by Warrants or Rights Represented as Percentage of Company’s Outstanding Common Stock |  |  |  | 12.00%
Riverside, Missouri [Member] |  |  |  |
Area of Real Estate Property (Square Foot) | ft² |  | 19,136 |  |
Sublease Agreement [Member] |  |  |  |
Operating Lease, Gain (Loss) | $ |  |  | $ 54 |
KBSIII Towers [Member] |  |  |  |
Lessee, Operating Lease, Renewal Term (Year) |  | 5 years |  |

X
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