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Note 3 - Business Combination - Pro Forma Financial Information (Details) - DERMAdoctor [Member] - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2021 | Dec. 31, 2020
Revenue | $ 12,767 | $ 18,170
Net Profit (Loss) | $ (4,918) | $ (11,647)

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