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Note 18 - Income Taxes (Tables) | 12 Months Ended
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Dec. 31, 2021
Notes Tables |
Schedule of Income before Income Tax, Domestic and Foreign [Table Text Block] |
|  | Year Ended December 31, |
|  | 2021 |  |  | 2020 |  |  | 2019 |
United States |  | $ | (5,824 | ) |  | $ | (11,034 | ) |  | $ | (9,652 | )
International |  |  | — |  |  |  | — |  |  |  | — |
|  | $ | (5,824 | ) |  | $ | (11,034 | ) |  | $ | (9,652 | )
Schedule of Components of Income Tax Expense (Benefit) [Table Text Block] |
|  | Year Ended December 31, |
|  | 2021 |  |  | 2020 |  |  | 2019 |
Current |  |  |  |  |  |  |  |  |  |  |  |
Federal |  | $ | — |  |  | $ | — |  |  | $ | — |
State |  |  | — |  |  |  | 5 |  |  |  | 6 |
Other |  |  | — |  |  |  | — |  |  |  | — |
Total current tax expense |  |  | — |  |  |  | 5 |  |  |  | 6 |
Deferred |  |  |  |  |  |  |  |  |  |  |  |
Federal |  |  | — |  |  |  | — |  |  |  | — |
State |  |  | — |  |  |  | — |  |  |  | — |
Other |  |  | — |  |  |  | — |  |  |  | — |
Total deferred tax expense |  |  | — |  |  |  | — |  |  |  | — |
Income tax provision |  | $ | — |  |  | $ | 5 |  |  | $ | 6 |
Schedule of Deferred Tax Assets and Liabilities [Table Text Block] |
|  | Year Ended December 31, |
|  | 2021 |  |  | 2020 |
Deferred tax assets: |  |  |  |  |  |  |  |
Net operating losses |  | $ | 33,455 |  |  | $ | 31,115 |
Stock options |  |  | 884 |  |  |  | 790 |
Research and development credits |  |  | 641 |  |  |  | 641 |
Accruals |  |  | 306 |  |  |  | 267 |
Operating lease liabilities |  |  | 19 |  |  |  | 109 |
Property and equipment |  |  | 10 |  |  |  | 2 |
Other deferred tax assets |  |  | 376 |  |  |  | 81 |
Total deferred tax assets |  |  | 35,691 |  |  |  | 33,005 |
Deferred tax liabilities: |  |  |  |  |  |  |  |
Operating lease right-of-use assets |  |  | (19 | ) |  |  | (108 | )
Total deferred tax liabilities |  |  | (19 | ) |  |  | (108 | )
Valuation allowance |  |  | (35,672 | ) |  |  | (32,897 | )
Net deferred taxes |  | $ | — |  |  | $ | — |
Summary of Operating Loss Carryforwards and Tax Credit Carryforwards [Table Text Block] |
|  |  |  |  |  | Expiration |
|  | Amount |  |  | Years |
Net operating losses, federal (Post December 31, 2017) |  | $ | 30,989 |  |  | Does Not Expire |
Net operating losses, federal (Pre January 1, 2018) |  | $ | 94,886 |  |  | Beginning in 2024 |
Net operating losses, state |  | $ | 106,784 |  |  | Beginning in 2028 |
Tax credits, federal |  | $ | 1,321 |  |  | Beginning in 2026 |
Tax credits, state |  | $ | 325 |  |  | Indefinite |
Schedule of Unrecognized Tax Benefits Roll Forward [Table Text Block] |
|  | Year Ended December 31, |
|  | 2021 |  |  | 2020 |
Unrecognized benefit - beginning of period |  | $ | 974 |  |  | $ | 974 |
Change during the period |  |  | — |  |  |  | — |
Unrecognized benefit - end of period |  | $ | 974 |  |  | $ | 974 |
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block] |
|  | Year Ended December 31, |
|  | 2021 |  |  | 2020 |  |  | 2019 |
Statutory rate |  |  | 21.0 | % |  |  | 21.0 | % |  |  | 21.0 | %
State tax |  |  | 11.2 | % |  |  | 3.2 | % |  |  | 3.1 | %
Change in valuation allowance |  |  | (47.7 | %) |  |  | (11.7 | %) |  |  | (23.0 | %)
Warrant/equity expenses |  |  | 16.7 | % |  |  | (10.3 | %) |  |  | 1.7 | %
Stock-based compensation expense |  |  | (1.1 | %) |  |  | (4.0 | %) |  |  | (3.7 | %)
Other |  |  | (0.1 | %) |  |  | 1.7 | % |  |  | (0.3 | %)
Impact of 162m |  |  | — | % |  |  | — | % |  |  | 1.1 | %
Total |  |  | 0.0 | % |  |  | (0.1 | %) |  |  | (0.1 | %)

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