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Note 4 - Fair Value Measurements - Fair Value of Warrant Liability (Details) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2021 | Dec. 31, 2020
Fair value of warrant liability at December 31, 2020 | $ 0 | $ 4,092
Fair value of warrant liability at December 31, 2021 | 9,558 | 0
Issuance Elimination of embedded derivative liability upon settlement of convertible noteWarrants |  | (1)
Warrant Liability [Member] |  |
Fair value of 2021 Warrants issued | 14,172 |
Decrease in fair value of 2021 Warrants | $ (4,614) | 5,238
Embedded Derivative Liability [Member] |  |
Decrease in fair value of 2021 Warrants |  | (2)
Expiration of Warrants [Member] |  |
Decrease in fair value of 2021 Warrants |  | (22)
The 2019 Preferred Warrant and 2019 Common Warrant Liability [Member] |  |
Fair value of warrant liability transferred to equity |  | (9,108)
The 2019 Ladenburg Warrants [Member] |  |
Fair value of warrant liability transferred to equity |  | $ (197)

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- Definition Amount of gain (loss) recognized in income from liability measured at fair value on recurring basis using unobservable input (level 3). + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI http://asc.fasb.org/extlink&oid=123874694&loc=d3e19207-110258 + Details
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- Definition Amount of issuances of financial instrument classified as a liability measured using unobservable inputs that reflect the entity's own assumption about the assumptions market participants would use in pricing. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(2) -URI http://asc.fasb.org/extlink&oid=123874694&loc=d3e19207-110258 + Details
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- Definition Amount of settlements of financial instrument classified as a liability measured using unobservable inputs that reflect the entity's own assumption about the assumptions market participants would use in pricing. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(2) -URI http://asc.fasb.org/extlink&oid=123874694&loc=d3e19207-110258 + Details
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- Definition Amount of transfers of financial instrument classified as a liability into (out of) level 3 of the fair value hierarchy. + References No definition available. + Details
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