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Note 2 - Summary of Significant Accounting Policies (Tables) | 12 Months Ended
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Dec. 31, 2021
Notes Tables |
Schedule of Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents [Table Text Block] |
|  | December 31, |  |  | December 31, |
|  | 2021 |  |  | 2020 |
Cash and cash equivalents |  | $ | 7,504 |  |  | $ | 11,952 |
Restricted cash included in other assets |  |  | 475 |  |  |  | 475 |
Total cash, cash equivalents, and restricted cash in the consolidated statements of cash flows |  | $ | 7,979 |  |  | $ | 12,427 |
Schedules of Concentration of Risk, by Product [Table Text Block] |
|  | Year Ended December 31, |
|  | 2021 |  |  | 2020 |  |  | 2019 |
Avenova Spray |  | $ | 6,844 |  |  | $ | 5,974 |  |  | $ | 6,347 |
DERMAdoctor |  |  | 587 |  |  |  | — |  |  |  | — |
KN95 Masks |  |  | — |  |  |  | 3,124 |  |  |  | — |
NeutroPhase |  |  | 368 |  |  |  | 524 |  |  |  | 209 |
Other products |  |  | 598 |  |  |  | 294 |  |  |  | — |
Total product revenue, net |  |  | 8,397 |  |  |  | 9,916 |  |  |  | 6,556 |
Other revenue, net |  |  | 24 |  |  |  | 18 |  |  |  | 43 |
Total sales, net |  | $ | 8,421 |  |  | $ | 9,934 |  |  | $ | 6,599 |
Schedules of Concentration of Risk, by Risk Factor [Table Text Block] |
|  | Year Ended December 31, |
Major distribution |  | 2021 |  |  | 2020 |  |  | 2019 |
Avenova Direct via Amazon |  |  | 59 | % |  |  | 50 | % |  |  | 15 | %
Avenova distributor A |  |  | * | % |  |  | * | % |  |  | 17 | %
Avenova distributor B |  |  | * | % |  |  | * | % |  |  | 16 | %
Avenova distributor C |  |  | * | % |  |  | * | % |  |  | 15 | %
|  | Year Ended December 31, |
Major distribution partner |  | 2021 |  |  | 2020 |
Major U.S. Retailer |  |  | 33 | % |  |  | * | %
Avenova Spray Pharmacy Distributor A |  |  | 13 | % |  |  | 18 | %
Avenova Spray Pharmacy Distributor C |  |  | 11 | % |  |  | 14 | %
Chongqing Pioneer Pharma Holdings Limited |  |  | * | % |  |  | 16 | %
Avenova Spray Pharmacy Distributor B |  |  | * | % |  |  | 14 | %
Amazon |  |  | * | % |  |  | 11 | %
Schedule of Intangible Assets and Goodwill [Table Text Block] |
Intangible Asset |  | Fair Value (in thousands) |  |  | Useful Life (in years) |  |  | Amortization Method |
Customer relationships |  | $ | 290 |  |  |  | 7 |  |  | Straight line |
Trade secrets / product formulations |  |  | 2,890 |  |  |  | 9 |  |  | Straight line |
Trade names |  |  | 2,080 |  |  | Indefinite |  |  |  | N/A |
Goodwill |  |  | 4,528 |  |  | Indefinite |  |  |  | N/A |
|  | $ | 9,788 |  |  |  |  |  |  |  |  |
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] |
|  | Year Ended December 31, |
|  | 2021 |  |  | 2020 |  |  | 2019 |
Numerator |  |  |  |  |  |  |  |  |  |  |  |
Net loss |  | $ | (5,824 | ) |  | $ | (11,039 | ) |  | $ | (9,658 | )
Less: Preferred deemed dividend |  |  | 735 |  |  |  | — |  |  |  | 800 |
Less: Retained earnings reduction related to warrants down round feature triggered |  |  | — |  |  |  | — |  |  |  | 29 |
Net loss attributable to common stockholders, basic and diluted |  | $ | (6,559 | ) |  | $ | (11,039 | ) |  | $ | (10,487 | )
Denominator |  |  |  |  |  |  |  |  |  |  |  |
Weighted average shares outstanding, basic and diluted |  |  | 43,657 |  |  |  | 35,076 |  |  |  | 21,641 |
Net loss per share, basic and diluted |  | $ | (0.15 | ) |  | $ | (0.31 | ) |  | $ | (0.48 | )
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] |
|  | Year Ended December 31, |
|  | 2021 |  |  | 2020 |  |  | 2019 |
Stock options |  | 4,449 |  |  |  | 3,165 |  |  |  | 2,183 |
Stock warrants |  |  | 7,082 |  |  |  | 7,067 |  |  |  | 8,588 |
|  |  | 11,531 |  |  |  | 10,232 |  |  |  | 10,771 |

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