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Note 2 - Summary of Significant Accounting Policies (Tables)

12 Months Ended

Dec. 31, 2021

Notes Tables

Schedule of Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents [Table Text Block]

		December 31,				December 31,
		2021				2020
Cash and cash equivalents		$	7,504			$	11,952
Restricted cash included in other assets			475				475
Total cash, cash equivalents, and restricted cash in the consolidated statements of cash flows		$	7,979			$	12,427

Schedules of Concentration of Risk, by Product [Table Text Block]

		Year Ended December 31,
		2021				2020				2019
Avenova Spray		$	6,844			$	5,974			$	6,347
DERMAdoctor			587				—				—
KN95 Masks			—				3,124				—
NeutroPhase			368				524				209
Other products			598				294				—
Total product revenue, net			8,397				9,916				6,556
Other revenue, net			24				18				43
Total sales, net		$	8,421			$	9,934			$	6,599

Schedules of Concentration of Risk, by Risk Factor [Table Text Block]

		Year Ended December 31,
Major distribution		2021				2020				2019
Avenova Direct via Amazon			59	%			50	%			15	%
Avenova distributor A			*	%			*	%			17	%
Avenova distributor B			*	%			*	%			16	%
Avenova distributor C			*	%			*	%			15	%

		Year Ended December 31,
Major distribution partner		2021				2020
Major U.S. Retailer			33	%			*	%
Avenova Spray Pharmacy Distributor A			13	%			18	%
Avenova Spray Pharmacy Distributor C			11	%			14	%
Chongqing Pioneer Pharma Holdings Limited			*	%			16	%
Avenova Spray Pharmacy Distributor B			*	%			14	%
Amazon			*	%			11	%

Schedule of Intangible Assets and Goodwill [Table Text Block]

Intangible Asset

Fair Value (in thousands)

Useful Life (in years)

Amortization Method

Customer relationships

$

290

7

Straight line

Trade secrets / product formulations

2,890

9

Straight line

Trade names

2,080

Indefinite

N/A

Goodwill

4,528

Indefinite

N/A

$

9,788

Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]

		Year Ended December 31,
		2021				2020				2019
Numerator
Net loss		$	(5,824	)		$	(11,039	)		$	(9,658	)
Less: Preferred deemed dividend			735				—				800
Less: Retained earnings reduction related to warrants down round feature triggered			—				—				29
Net loss attributable to common stockholders, basic and diluted		$	(6,559	)		$	(11,039	)		$	(10,487	)
Denominator
Weighted average shares outstanding, basic and diluted			43,657				35,076				21,641
Net loss per share, basic and diluted		$	(0.15	)		$	(0.31	)		$	(0.48	)

Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]

		Year Ended December 31,
		2021				2020				2019
Stock options		4,449					3,165				2,183
Stock warrants			7,082				7,067				8,588
			11,531				10,232				10,771

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