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Consolidated Statements of Stockholders' Equity - USD ($)
Series A Preferred Stock [Member]
Preferred Stock [Member]
Series A Preferred Stock [Member]
Common Stock [Member]
Series A Preferred Stock [Member]
Additional Paid-in Capital [Member]
Series A Preferred Stock [Member]
Nonemployees [Member]
Common Stock [Member]
Nonemployees [Member]
Additional Paid-in Capital [Member]
Nonemployees [Member]
Employee [Member]
Common Stock [Member]
Employee [Member]
Additional Paid-in Capital [Member]
Employee [Member]
Preferred Stock [Member]
Common Stock [Member]
Additional Paid-in Capital [Member]
Retained Earnings [Member]
Total
Balance (in shares) at Dec. 31, 2018                     0 17,089,000      
Balance at Dec. 31, 2018                     $ 0 $ 171,000 $ 119,764,000 $ (114,981,000) $ 4,954,000
Net loss                           (9,658,000) (9,658,000)
Reclassification of warrant liability to equity                     $ 0   412,000 (356,000) 56,000
Down round feature adjustment related to warrants                         29,000 (29,000)  
Issuance of preferred stock and common stock warrants, net of offering costs (in shares) 2,700,000                            
Issuance of preferred stock and common stock warrants, net of offering costs $ 584,000                            
Conversion of preferred stock to common stock (in shares) (2,700,000) 2,700,000                          
Conversion of preferred stock to common stock $ (584,000)                           (584,000)
Conversion of preferred stock to common stock   $ 27,000 $ 557,000 $ 584,000                      
Beneficial conversion feature upon issuance of preferred stock     800,000 800,000                      
Deemed dividend from beneficial conversion feature of preferred stock     (800,000) (800,000)                      
Issuance of common stock in connection with offering, net of offering costs (in shares)                       7,467,000      
Issuance of common stock in connection with offering, net of offering costs                       $ 75,000 3,427,000   3,502,000
Issuance of common stock in connection with exercise of warrants (in shares)                       389,000      
Issuance of common stock in connection with exercise of warrants                       $ 4,000 616,000   620,000
Issuance of RSUs related to employee separation agreement (in shares)                       168,000      
Issuance of RSUs related to employee separation agreement                       $ 2,000 218,000   $ 220,000
Issuance of common stock for option exercises (in shares)                       83,000     83,000
Issuance of common stock for option exercises                         189,000   $ 189,000
Issuance of RSUs (in shares)         36,000     6,000              
Issuance of RSUs           $ 20,000 $ 20,000   $ 10,000 $ 10,000          
Stock-based compensation expense related to employee and director stock options                         334,000   334,000
Stock-based compensation expense related to non-employee stock options                         37,000   37,000
Stock option modification                         105,000   105,000
Deemed dividend from beneficial conversion feature of preferred stock     $ 800,000 $ 800,000                      
Balance (in shares) at Dec. 31, 2019                     0 27,938,000      
Balance at Dec. 31, 2019                     $ 0 $ 279,000 125,718,000 (125,024,000) 973,000
Net loss                           (11,039,000) (11,039,000)
Reclassification of warrant liability to equity                         197,000   197,000
Conversion of preferred stock to common stock                             0
Issuance of common stock in connection with offering, net of offering costs (in shares)                       5,838,000      
Issuance of common stock in connection with offering, net of offering costs                       $ 58,000 5,162,000   5,220,000
Issuance of common stock in connection with exercise of warrants (in shares)                       7,791,000      
Issuance of common stock in connection with exercise of warrants                       $ 78,000 16,128,000   $ 16,206,000
Issuance of common stock for option exercises (in shares)                       20,000     20,000
Issuance of common stock for option exercises                       $ 1,000 6,000   $ 7,000
Issuance of RSUs (in shares)         193,000     2,000              
Issuance of RSUs         $ 2,000 218,000 220,000   $ 2,000 $ 2,000          
Stock-based compensation expense related to employee and director stock options                         415,000   415,000
Stock-based compensation expense related to non-employee stock options                         64,000   64,000
Stock option modification                         53,000   53,000
Balance (in shares) at Dec. 31, 2020                     0 41,782,000      
Balance at Dec. 31, 2020                     $ 0 $ 418,000 147,963,000 (136,063,000) 12,318,000
Net loss                           (5,824,000) (5,824,000)
Issuance of preferred stock and common stock warrants, net of offering costs (in shares)                     15        
Issuance of preferred stock and common stock warrants, net of offering costs                     $ 735       735
Conversion of preferred stock to common stock (in shares)                     (1,000) 2,823,000      
Conversion of preferred stock to common stock                     $ (55,000)       (55,000)
Conversion of preferred stock to common stock                       $ 28,000 27,000    
Beneficial conversion feature upon issuance of preferred stock                         735,000   735,000
Deemed dividend from beneficial conversion feature of preferred stock                         735,000   735,000
Issuance of common stock in connection with offering, net of offering costs (in shares)                       2,673,000      
Issuance of common stock in connection with offering, net of offering costs                       $ 27,000 1,749,000   $ 1,776,000
Issuance of common stock for option exercises (in shares)                             0
Issuance of RSUs (in shares)         328,000             160      
Issuance of RSUs         $ 3,000 $ 217,000 $ 220,000         $ 2 (2)    
Stock-based compensation expense related to employee and director stock options                         693,000   $ 693,000
Stock-based compensation expense related to non-employee stock options                         240,000   240,000
Issuance of warrants                         13,000   13,000
Deemed dividend from beneficial conversion feature of preferred stock                         (735,000)   (735,000)
Balance (in shares) at Dec. 31, 2021                     14,000 47,766,000      
Balance at Dec. 31, 2021                     $ 680,000 $ 478,000 $ 150,900,000 $ (141,887,000) $ 10,171,000