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Note 16 - License, Collaboration and Distribution Agreements - Changes in Assets and Liabilities (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Contract Liabilities: Deferred Revenue, Balance at beginning of the period $ 2 $ 0
Contract Liabilities: Deferred Revenue, additions 176 2
Contract Liabilities: Deferred Revenue, deductions (124) 0
Contract Liabilities: Deferred Revenue, Balance at the end of the period 54 2
Contract Liabilities: Accrued Liabilities,Balance at beginning of the period 573 434
Contract Liabilities: Accrued Liabilities, additions 1,851 2,338
Contract Liabilities: Accrued Liabilities, deductions (1,154) (2,199)
Contract Liabilities: Accrued Liabilities, Balance at the end of the period 1,270 573
Contract Liabilities, Balance at beginning of the period 575 434
Contract Liabilities, additions 2,027 2,340
Contract Liabilities, deductions (1,278) (2,199)
Contract Liabilities, Balance at the end of the period $ 1,324 $ 575