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Note 15 - Equity-based Compensation - Weighted-average Assumptions Used in Determining the Value of Options Granted to Employees and Directors (Details) - Employees and Directors [Member] - $ / shares
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Expected price volatility 160.47% 164.44%
Expected term (Year) 6 years 5 months 12 days 6 years 2 months 8 days
Risk-free interest rate 1.63% 1.09%
Dividend yield 0.00% 0.00%
Weighted-average fair value of options granted during the period (in dollars per share) $ 0.29 $ 1.04