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Note 16 - License, Collaboration and Distribution Agreements (Details Textual) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021	Dec. 31, 2021
Revenue from Contract with Customer, Including Assessed Tax	$ 2,629	$ 1,807
Avenova Direct [Member]
Revenue from Contract with Customer, Including Assessed Tax	1,400	1,200
DERMAdoctor [Member]
Contract with Customer, Liability, Total	600		$ 400
Revenue from Contract with Customer, Including Assessed Tax	891	0
McKesson Corporation [Member] | Avenova Product [Member]
Contract with Customer, Liability, Revenue Recognized	199	$ 122
McKesson Corporation [Member] | Avenova Product [Member] | Accounts Payable and Accrued Liabilities [Member]
Contract with Customer, Liability, Total	1,300		900
McKesson Corporation [Member] | Avenova Product [Member] | Prepaid Expenses and Other Current Assets [Member]
Contract with Customer, Rebate Liability, Current	$ 3		$ 19

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