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Note 2 - Summary of Significant Accounting Policies - Outstanding Stock Options and Stock Warrants Excluded From the Diluted Net Loss Per Share Computation (Details) - shares | 6 Months Ended
--- | ---
Jun. 30, 2022 | Jun. 30, 2021
Anti-dilutive securities (in shares) | 78,078,000 | 10,955,000
Series B Preferred [Member] |  |
Anti-dilutive securities (in shares) | 29,050 | 0
Share-Based Payment Arrangement, Option [Member] |  |
Anti-dilutive securities (in shares) | 4,446,000 | 3,873,000
Warrant [Member] |  |
Anti-dilutive securities (in shares) | 44,582,000 | 7,082,000

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- Definition Securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) or earnings per unit (EPU) in the future that were not included in the computation of diluted EPS or EPU because to do so would increase EPS or EPU amounts or decrease loss per share or unit amounts for the period presented. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (c) -URI https://asc.fasb.org/extlink&oid=124432515&loc=d3e3550-109257 + Details
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