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Note 16 - License, Collaboration and Distribution Agreements (Details Textual) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
Dec. 31, 2021
Revenue from Contract with Customer, Including Assessed Tax $ 3,045 $ 2,133 $ 5,674 $ 3,940  
Avenova Direct [Member]          
Revenue from Contract with Customer, Including Assessed Tax 1,300 1,300 2,700 2,600  
DERMAdoctor [Member]          
Contract with Customer, Liability, Total 100   100   $ 400
Revenue from Contract with Customer, Including Assessed Tax 592 0 1,483 0  
McKesson Corporation [Member] | Avenova Product [Member]          
Contract with Customer, Liability, Revenue Recognized 100 $ 300 57 $ 385  
McKesson Corporation [Member] | Avenova Product [Member] | Accounts Payable and Accrued Liabilities [Member]          
Contract with Customer, Liability, Total 1,400   1,400   900
McKesson Corporation [Member] | Avenova Product [Member] | Prepaid Expenses and Other Current Assets [Member]          
Contract with Customer, Rebate Liability, Current $ 6   $ 6   $ 19