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Note 14 - Stockholders' Equity (Details Textual) $ / shares in Units, $ in Thousands |  |  | 3 Months Ended | 4 Months Ended | 9 Months Ended | 12 Months Ended |  |  |  |  |  |
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Sep. 09, 2022 USD ($) $ / shares shares | Oct. 29, 2021 USD ($) $ / shares shares | Sep. 30, 2022 USD ($) $ / shares shares | Dec. 31, 2021 USD ($) $ / shares shares | Sep. 30, 2021 USD ($) | Jun. 30, 2021 USD ($) shares | Sep. 30, 2020 USD ($) $ / shares shares | Sep. 30, 2019 USD ($) $ / shares shares | Dec. 31, 2022 USD ($) | Sep. 30, 2022 USD ($) $ / shares shares | Sep. 30, 2021 USD ($) | Dec. 31, 2021 USD ($) $ / shares shares | Sep. 08, 2022 USD ($) $ / shares | Nov. 30, 2021 $ / shares | Nov. 02, 2021 USD ($) | Jan. 15, 2021 $ / shares shares | Dec. 31, 2020 USD ($) | Aug. 13, 2019 USD ($)
Common Stock, Shares Authorized (in shares) | shares |  |  | 150,000,000 | 100,000,000 |  |  |  |  |  | 150,000,000 |  | 100,000,000 |  |  |  |  |  |
Preferred Stock, Shares Authorized (in shares) | shares |  |  | 5,000,000 | 5,000,000 |  |  |  |  |  | 5,000,000 |  | 5,000,000 |  |  |  |  |  |
Gain (Loss) on Modification of Warrants |  |  | $ (1,922) |  | $ 0 |  |  |  |  | $ (1,922) | $ 0 |  |  |  |  |  |  |
Class of Warrant or Right, Exercised During Period (in shares) | shares |  |  |  |  |  |  |  |  |  | 11,475,000 |  |  |  |  |  |  |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares |  |  | $ 1.59 | $ 1.63 |  |  |  |  |  | $ 1.59 |  | $ 1.63 |  |  |  |  |  |
Proceeds from Warrant Exercises |  |  |  |  |  |  | $ 6,800 |  |  | $ 1,703 | 0 |  |  |  |  |  |  |
Payments of Stock Issuance Costs |  |  |  |  |  |  | 200 |  |  |  |  |  |  |  |  |  |  |
Preferred Stock, Par or Stated Value Per Share (in dollars per share) | $ / shares |  |  | $ 0.01 | $ 0.01 |  |  |  |  |  | $ 0.01 |  | $ 0.01 |  |  |  |  |  |
Preferred Stock, Change in Conversion Price, Income Statement Impact |  |  | $ 5,657 |  | $ 0 |  |  |  |  | $ 5,657 | 0 |  |  |  |  |  |  |
Preferred Stock, Shares Outstanding, Ending Balance (in shares) | shares |  |  | 12,000 | 14,000 |  |  |  |  |  | 12,000 |  | 14,000 |  |  |  |  |  |
Class of Warrant or Right, Outstanding (in shares) | shares |  |  | 2,282,000 | 7,082,000 |  |  |  |  |  | 2,282,000 |  | 7,082,000 |  |  |  |  |  |
Class of Warrant or Right, Issued During Period (in shares) | shares |  |  |  |  |  |  |  |  |  | 37,500,000 |  |  |  |  |  |  |  |
Proceeds from Issuance of Common Stock |  |  |  |  |  |  |  |  |  |  | $ 1,994 |  |  |  |  |  |  |
Conversion of Series B Preferred Stock to Common Stock [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Adjustments to Additional Paid in Capital, Beneficial Conversion Feature Upon Issuance of Stock |  |  |  | $ 700 |  |  |  |  |  |  |  |  |  |  |  |  |  |
The 2021 Private Placement Program [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Payments of Stock Issuance Costs |  |  |  |  |  |  |  |  |  |  |  | $ 1,700 |  |  |  |  |  |
Payments of Stock Issuance Costs Allocated to Warrants |  |  |  |  |  |  |  |  |  |  |  | 1,600 |  |  |  |  |  |
The 2021 Private Placement Program [Member] | Conversion of Series B Preferred Stock to Common Stock [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Preferred Stock, Convertible, Shares Issuable (in shares) | shares |  | 37,500,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Preferred Stock, Convertible, Conversion Price (in dollars per share) | $ / shares |  | $ 0.40 | $ 0.40 |  |  |  |  |  |  | $ 0.40 |  |  |  |  |  |  |  |
Preferred Stock, Convertible, Conversion Ratio |  | 2,500 | 2,500 |  |  |  |  |  |  | 2,500 |  |  |  |  |  |  |  |
Conversion of Stock, Shares Converted (in shares) | shares |  |  |  |  |  |  |  |  |  | 3,380 |  |  |  |  |  |  |  |
Conversion of Stock, Shares Issued (in shares) | shares |  |  |  |  |  |  |  |  |  | 8,450,000 |  |  |  |  |  |  |  |
August 2019 Common Stock Purchase Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Payments of Stock Issuance Costs |  |  |  |  |  |  |  | $ 500 |  |  |  |  |  |  |  |  |  |
Proceeds from Issuance or Sale of Equity, Total |  |  |  |  |  |  |  | $ 4,200 |  |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, New Issues (in shares) | shares |  |  |  |  |  |  |  | 4,198,566 |  |  |  |  |  |  |  |  |  |
August 2019 Common Stock Purchase Agreement 2 [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from Issuance or Sale of Equity, Total |  |  |  |  |  |  |  | $ 2,700 |  |  |  |  |  |  |  |  |  |
ATM Program [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Payments of Stock Issuance Costs |  |  |  |  |  | $ 100 |  |  |  |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, New Issues (in shares) | shares |  |  |  |  |  | 2,672,000 |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from Issuance of Common Stock |  |  |  |  |  | $ 1,800 |  |  |  |  |  |  |  |  |  |  |  |
Series C Preferred Stock [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Preferred Stock, Par or Stated Value Per Share (in dollars per share) | $ / shares | $ 0.01 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Series C Preferred Stock [Member] | Forecast [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from Issuance or Sale of Equity, Total |  |  |  |  |  |  |  |  | $ 3,300 |  |  |  |  |  |  |  |  |
Series B Preferred Stock [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Preferred Stock, Convertible, Conversion Price (in dollars per share) | $ / shares | $ 0.18 |  |  |  |  |  |  |  |  |  |  |  | $ 0.40 |  |  |  |  |
Convertible Preferred Stock, Shares Issued upon Conversion (in shares) | shares | 5,556 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Preferred Stock, Change in Conversion Price, Income Statement Impact | $ 5,700 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Preferred Stock, Fair Value Disclosure | 12,500 |  |  |  |  |  |  |  |  |  |  |  | $ 6,900 |  |  |  |  |
Series B Preferred Stock [Member] | The 2021 Private Placement Program [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs |  |  |  |  |  |  |  |  |  |  |  | 100 |  |  |  |  |  |
Stock Issued During Period, Shares, New Issues (in shares) | shares |  | 15,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from Issuance of Preferred Stock and Preference Stock |  | $ 14,900 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Preferred Stock, Purchase Price (in dollars per share) | $ / shares |  | $ 1,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Preferred Stock, Convertible, Conversion Price (in dollars per share) | $ / shares |  |  | $ 0.18 |  |  |  |  |  |  | $ 0.18 |  |  |  |  |  |  |  |
Convertible Preferred Stock, Shares Issued upon Conversion (in shares) | shares |  |  | 5,556 |  |  |  |  |  |  | 5,556 |  |  |  |  |  |  |  |
Preferred Stock, Shares Outstanding, Ending Balance (in shares) | shares |  |  | 11,620 |  |  |  |  |  |  | 11,620 |  |  |  |  |  |  |  |
Series A Preferred Stock [Member] | August 2019 Common Stock Purchase Agreement 2 [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, New Issues (in shares) | shares |  |  |  |  |  |  |  | 2,700,000 |  |  |  |  |  |  |  |  |  |
Ladenburg Thalmann and Co. Inc. [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Payments of Stock Issuance Costs |  |  |  |  |  |  |  | $ 300 |  |  |  |  |  |  |  |  |  |
Private Placement, Commission Percentage |  |  |  |  |  |  |  | 6.00% |  |  |  |  |  |  |  |  |  |
Payments of Stock Issuance Costs, Reimbursement of Expenses |  |  |  |  |  |  |  | $ 60 |  |  |  |  |  |  |  |  |  |
Payments of Stock Issuance Costs, Other |  |  |  |  |  |  |  | 300 |  |  |  |  |  |  |  |  |  |
China Kington [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Payments of Stock Issuance Costs |  |  |  |  |  |  | $ 200 |  |  |  |  |  |  |  |  |  |  |
The July 2020 and November 2021 Warrants [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Gain (Loss) on Modification of Warrants | (1,900) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Warrants and Rights Outstanding | 5,200 |  |  |  |  |  |  |  |  |  |  |  | $ 3,300 |  |  |  |  |
The November 2021 Warrants [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Warrants and Rights Outstanding | $ 3,500 |  | $ 1,900 |  |  |  |  |  |  | $ 1,900 |  |  |  |  |  |  |  |
Class of Warrant or Right, Exercised During Period (in shares) | shares | 9,375,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares | $ 0.18 |  |  |  |  |  |  |  |  |  |  |  |  | $ 0.53 |  |  |  |
Proceeds from Warrant Exercises | $ 700 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Outstanding (in shares) | shares |  |  | 28,125,000 |  |  |  |  |  |  | 28,125,000 |  |  |  |  |  |  |  |
Class of Warrant or Right, Excluded from Outstanding Balance (in shares) | shares |  |  | 28,125,000 |  |  |  |  |  |  | 28,125,000 |  |  |  |  |  |  |  |
Amended July 2020 Warrants [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Warrants and Rights Outstanding | $ 300 |  | $ 100 |  |  |  |  |  |  | $ 100 |  |  |  |  |  |  |  |
Class of Warrant or Right, Exercised During Period (in shares) | shares | 2,100,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) | shares | 4,800,000 |  | 4,800,000 |  |  |  |  |  |  | 4,800,000 |  |  |  |  |  |  |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares | $ 0.18 |  | $ 0.18 |  |  |  |  |  |  | $ 0.18 |  |  |  |  |  |  |  |
Proceeds from Warrant Exercises | $ 1,400 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Outstanding (in shares) | shares | 2,700,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Excluded from Outstanding Balance (in shares) | shares |  |  | 2,700,000 |  |  |  |  |  |  | 2,700,000 |  |  |  |  |  |  |  |
The 2022 Warrant Reprice Transaction [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) | shares | 11,475,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares | $ 0.18 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from Warrant Exercises | $ 2,100 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Payments of Stock Issuance Costs | 529 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Payments of Stock Issuance Costs Allocated to Warrants | 166 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs | $ 363 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
The 2022 Warrant Reprice Transaction [Member] | Ladenburg Thalmann and Co. Inc. [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Exercise of Warrants, Commission, Percent | 8.00% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
The 2021 Warrants [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Warrants and Rights Outstanding |  |  |  | $ 9,600 |  |  |  |  |  |  |  | $ 9,600 |  |  | $ 14,200 |  |  |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) | shares |  | 37,500,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
September 2022 Warrants [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Warrants and Rights Outstanding | $ 1,400 |  | $ 800 |  |  |  |  |  |  | $ 800 |  |  |  |  |  |  |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares | $ 0.18 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Excluded from Outstanding Balance (in shares) | shares |  |  | 11,475,000 |  |  |  |  |  |  | 11,475,000 |  |  |  |  |  |  |  |
The 2019 Domestic Warrants [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Warrants and Rights Outstanding |  |  |  |  |  |  |  | $ 3,100 |  |  |  |  |  |  |  |  | $ 4,900 | $ 3,100
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares |  |  |  |  |  |  |  | $ 1.15 |  |  |  |  |  |  |  |  |  |
Payments of Stock Issuance Costs Allocated to Warrants |  |  |  |  |  |  |  | $ 200 |  |  |  |  |  |  |  |  |  |
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs |  |  |  |  |  |  |  | $ 300 |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Outstanding (in shares) | shares |  |  | 0 |  |  |  |  |  |  | 0 |  |  |  |  |  |  |  |
The 2019 Domestic Warrants [Member] | August 2019 Common Stock Purchase Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) | shares |  |  |  |  |  |  |  | 4,198,566 |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Issued During Period (in shares) | shares |  |  |  |  |  |  |  | 4,198,566 |  |  |  |  |  |  |  |  |  |
The 2019 Foreign Warrants [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Warrants and Rights Outstanding |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 4,200 | 2,000
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares |  |  |  |  |  |  | $ 0.99 |  |  |  |  |  |  |  |  |  |  |
Exercise of Warrants, Commission, Percent |  |  |  |  |  |  | 6.00% |  |  |  |  |  |  |  |  |  |  |
The 2019 Foreign Warrants [Member] | August 2019 Common Stock Purchase Agreement 2 [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) | shares |  |  |  |  |  |  |  | 2,700,000 |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Issued During Period (in shares) | shares |  |  |  |  |  |  |  | 2,700,000 |  |  |  |  |  |  |  |  |  |
The 2019 Ladenburg Warrants [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Warrants and Rights Outstanding |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 200 | $ 100
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) | shares |  |  |  |  |  |  |  | 167,942 |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares |  |  |  |  |  |  | $ 0.99 | $ 1.25 |  |  |  |  |  |  |  |  |  |
Payments of Stock Issuance Costs Allocated to Warrants |  |  |  |  |  |  |  | $ 59 |  |  |  |  |  |  |  |  |  |
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs |  |  |  |  |  |  |  | $ 65 |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Issued During Period (in shares) | shares |  |  |  |  |  |  |  | 167,942 |  |  |  |  |  |  |  |  |  |
New Warrants [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) | shares |  |  |  |  |  |  | 6,898,566 |  |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares |  |  |  |  |  |  | $ 1.65 |  |  |  |  |  |  |  |  |  |  |
Warrants and Rights Outstanding, Term (Year) |  |  |  |  |  |  | 5 years 6 months |  |  |  |  |  |  |  |  |  |  |
Unamended July 2020 Warrants [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) | shares |  |  | 2,098,566 |  |  |  |  |  |  | 2,098,566 |  |  |  |  |  |  |  |
TLF Bio Innovation 2021 Warrants [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) | shares |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 15,000 |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 0.6718 |  |
Warrants and Rights Outstanding, Term (Year) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 5 years |  |

X
- Definition Amount of increase (decrease) in additional paid in capital (APIC) resulting from beneficial conversion feature upon issuance of stock. + References No definition available. + Details
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- Definition Represents the amount of cash outflow for cost incurred for items involved, but not directly tied with the issuance of an equity securities. + References No definition available. + Details
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