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Note 13 - Warrant Liability (Tables) | 12 Months Ended
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Dec. 31, 2022
Notes Tables |
Schedule of Derivative Instruments [Table Text Block] |
Expected price volatility |  |  | 79.6 | %
Expected term (in years) |  |  | 6.0 |
Risk-free interest rate |  |  | 3.43 | %
Dividend yield |  |  | 0.0 | %
Weighted-average fair value of warrants |  | $ | 4.55 |
Expected price volatility |  |  | 79.5 | %
Expected term (in years) |  |  | 5.8 |
Risk-free interest rate |  |  | 3.93 | %
Dividend yield |  |  | 0.0 | %
Weighted-average fair value of warrants |  | $ | 1.40 |
Expected price volatility |  |  | 84.9 | %
Expected term (in years) |  |  | 6.2 |
Risk-free interest rate |  |  | 1.29 | %
Dividend yield |  |  | 0.00 | %
Weighted-average fair value of warrants |  | $ | 13.30 |
Expected price volatility |  |  | 87 | %
Expected term (in years) |  |  | 6.0 |
Risk-free interest rate |  |  | 1.31 | %
Dividend yield |  |  | 0.00 | %
Weighted-average fair value of warrants |  | $ | 8.75 |
Expected price volatility |  |  | 79.6 | %
Expected term (in years) |  |  | 6.0 |
Risk-free interest rate |  |  | 3.43 | %
Dividend yield |  |  | 0.00 | %
Weighted-average fair value of warrants |  | $ | 4.55 |
Expected price volatility |  |  | 79.5 | %
Expected term (in years) |  |  | 5.8 |
Risk-free interest rate |  |  | 3.93 | %
Dividend yield |  |  | 0.00 | %
Weighted-average fair value of warrants |  | $ | 1.40 |
Expected price volatility |  |  | 79.6 | %
Expected term (in years) |  |  | 3.4 |
Risk-free interest rate |  |  | 3.58 | %
Dividend yield |  |  | 0.00 | %
Weighted-average fair value of warrants |  | $ | 3.50 |
Expected price volatility |  |  | 79.5 | %
Expected term (in years) |  |  | 3.2 |
Risk-free interest rate |  |  | 4.15 | %
Dividend yield |  |  | 0.00 | %
Weighted-average fair value of warrants |  | $ | 1.05 |
Assumptions |  | 2019 Domestic Warrants |  |  | 2019 Foreign Warrants |
Expected price volatility |  |  | 178 | % |  |  | 178 | %
Expected term (in years) |  |  | 4.57 |  |  |  | 4.57 |
Risk-free interest rate |  |  | 0.25 | % |  |  | 0.27 | %
Dividend yield |  |  | 0.00 | % |  |  | 0.00 | %
Weighted-average fair value of warrant |  | $ | 41.30 |  |  | $ | 53.90 |
Expected price volatility |  |  | 186 | %
Expected term (in years) |  |  | 4.05 |
Risk-free interest rate |  |  | 0.22 | %
Dividend yield |  |  | 0.00 | %
Weighted-average fair value of warrants |  | $ | 40.95 |

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