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Note 13 - Warrant Liability - The Key Assumptions Used to Value the Warrants (Details) | Nov. 10, 2022 | Sep. 09, 2022 | Sep. 08, 2022 | Dec. 31, 2021 | Nov. 02, 2021 | Dec. 31, 2019
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Measurement Input, Price Volatility [Member] | September 2022 Warrants [Member] |  |  |  |  |  |
Warrants assumptions | 0.795 | 0.796 |  |  |  |
Measurement Input, Price Volatility [Member] | The 2021 Warrants [Member] |  |  |  |  |  |
Warrants assumptions |  |  |  | 0.87 | 0.849 |
Measurement Input, Price Volatility [Member] | The November 2021 Warrants [Member] |  |  |  |  |  |
Warrants assumptions | 0.795 | 0.796 | 0.796 |  |  |
Measurement Input, Price Volatility [Member] | Amended July 2020 Warrants [Member] |  |  |  |  |  |
Warrants assumptions | 0.795 | 0.796 | 0.796 |  |  |
Measurement Input, Price Volatility [Member] | The 2019 Domestic Warrants [Member] |  |  |  |  |  |
Warrants assumptions |  |  |  |  |  | 1.78
Measurement Input, Price Volatility [Member] | The 2019 Foreign Warrants [Member] |  |  |  |  |  |
Warrants assumptions |  |  |  |  |  | 1.78
Measurement Input, Price Volatility [Member] | The 2019 Ladenburg Warrants [Member] |  |  |  |  |  |
Warrants assumptions |  |  |  |  |  | 1.86
Measurement Input, Expected Term [Member] | September 2022 Warrants [Member] |  |  |  |  |  |
Warrants assumptions | 5.8 | 6.0 |  |  |  |
Measurement Input, Expected Term [Member] | The 2021 Warrants [Member] |  |  |  |  |  |
Warrants assumptions |  |  |  | 6.0 | 6.2 |
Measurement Input, Expected Term [Member] | The November 2021 Warrants [Member] |  |  |  |  |  |
Warrants assumptions | 5.8 | 6.0 | 5.4 |  |  |
Measurement Input, Expected Term [Member] | Amended July 2020 Warrants [Member] |  |  |  |  |  |
Warrants assumptions | 3.2 | 3.4 | 3.4 |  |  |
Measurement Input, Expected Term [Member] | The 2019 Domestic Warrants [Member] |  |  |  |  |  |
Warrants assumptions |  |  |  |  |  | 4.57
Measurement Input, Expected Term [Member] | The 2019 Foreign Warrants [Member] |  |  |  |  |  |
Warrants assumptions |  |  |  |  |  | 4.57
Measurement Input, Expected Term [Member] | The 2019 Ladenburg Warrants [Member] |  |  |  |  |  |
Warrants assumptions |  |  |  |  |  | 4.05
Measurement Input, Risk Free Interest Rate [Member] | September 2022 Warrants [Member] |  |  |  |  |  |
Warrants assumptions | 0.0393 | 0.0343 |  |  |  |
Measurement Input, Risk Free Interest Rate [Member] | The 2021 Warrants [Member] |  |  |  |  |  |
Warrants assumptions |  |  |  | 0.0131 | 0.0129 |
Measurement Input, Risk Free Interest Rate [Member] | The November 2021 Warrants [Member] |  |  |  |  |  |
Warrants assumptions | 0.0393 | 0.0343 | 0.0343 |  |  |
Measurement Input, Risk Free Interest Rate [Member] | Amended July 2020 Warrants [Member] |  |  |  |  |  |
Warrants assumptions | 0.0415 | 0.0358 | 0.0358 |  |  |
Measurement Input, Risk Free Interest Rate [Member] | The 2019 Domestic Warrants [Member] |  |  |  |  |  |
Warrants assumptions |  |  |  |  |  | 0.0025
Measurement Input, Risk Free Interest Rate [Member] | The 2019 Foreign Warrants [Member] |  |  |  |  |  |
Warrants assumptions |  |  |  |  |  | 0.0027
Measurement Input, Risk Free Interest Rate [Member] | The 2019 Ladenburg Warrants [Member] |  |  |  |  |  |
Warrants assumptions |  |  |  |  |  | 0.0022
Measurement Input, Expected Dividend Rate [Member] | September 2022 Warrants [Member] |  |  |  |  |  |
Warrants assumptions | 0.000 | 0.000 |  |  |  |
Measurement Input, Expected Dividend Rate [Member] | The 2021 Warrants [Member] |  |  |  |  |  |
Warrants assumptions |  |  |  | 0.0000 | 0.0000 |
Measurement Input, Expected Dividend Rate [Member] | The November 2021 Warrants [Member] |  |  |  |  |  |
Warrants assumptions | 0.0000 | 0.0000 | 0.0000 |  |  |
Measurement Input, Expected Dividend Rate [Member] | Amended July 2020 Warrants [Member] |  |  |  |  |  |
Warrants assumptions | 0.0000 | 0.0000 | 0.0000 |  |  |
Measurement Input, Expected Dividend Rate [Member] | The 2019 Domestic Warrants [Member] |  |  |  |  |  |
Warrants assumptions |  |  |  |  |  | 0.0000
Measurement Input, Expected Dividend Rate [Member] | The 2019 Foreign Warrants [Member] |  |  |  |  |  |
Warrants assumptions |  |  |  |  |  | 0.0000
Measurement Input, Expected Dividend Rate [Member] | The 2019 Ladenburg Warrants [Member] |  |  |  |  |  |
Warrants assumptions |  |  |  |  |  | 0.0000
Measurement Input, Share Price [Member] | September 2022 Warrants [Member] |  |  |  |  |  |
Warrants assumptions | 1.40 | 4.55 |  |  |  |
Measurement Input, Share Price [Member] | The 2021 Warrants [Member] |  |  |  |  |  |
Warrants assumptions |  |  |  | 8.75 | 13.30 |
Measurement Input, Share Price [Member] | The November 2021 Warrants [Member] |  |  |  |  |  |
Warrants assumptions | 1.40 | 4.55 | 3.15 |  |  |
Measurement Input, Share Price [Member] | Amended July 2020 Warrants [Member] |  |  |  |  |  |
Warrants assumptions | 1.05 | 3.50 | 0.70 |  |  |
Measurement Input, Share Price [Member] | The 2019 Domestic Warrants [Member] |  |  |  |  |  |
Warrants assumptions |  |  |  |  |  | 41.30
Measurement Input, Share Price [Member] | The 2019 Foreign Warrants [Member] |  |  |  |  |  |
Warrants assumptions |  |  |  |  |  | 53.90
Measurement Input, Share Price [Member] | The 2019 Ladenburg Warrants [Member] |  |  |  |  |  |
Warrants assumptions |  |  |  |  |  | 40.95

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- Definition Value of input used to measure outstanding warrant and right embodying unconditional obligation requiring redemption by transferring asset at specified or determinable date or upon event certain to occur. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (bbb)(2) -URI https://asc.fasb.org/extlink&oid=126976982&loc=d3e19207-110258 + Details
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