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Note 16 - Distribution Agreements (Details Textual) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Contract with Customer, Liability, Total $ 4 $ 54 $ 2
Revenue from Contract with Customer, Including Assessed Tax 14,404 10,204  
Avenova Direct [Member]      
Revenue from Contract with Customer, Including Assessed Tax 6,500 6,600  
DERMAdoctor [Member]      
Contract with Customer, Liability, Total 200 400  
Revenue from Contract with Customer, Including Assessed Tax 4,155 649  
McKesson Corporation [Member] | Avenova Product [Member]      
Contract with Customer, Liability, Revenue Recognized 100 600  
McKesson Corporation [Member] | Avenova Product [Member] | Accounts Payable and Accrued Liabilities [Member]      
Contract with Customer, Liability, Total 1,600 900  
McKesson Corporation [Member] | Avenova Product [Member] | Prepaid Expenses and Other Current Assets [Member]      
Contract with Customer, Rebate Liability, Current 0 19  
Costco and Others [Member] | DERMAdoctor [Member]      
Revenue from Contract with Customer, Including Assessed Tax $ 900 $ 200