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Note 14 - Distribution Agreements (Details Textual) - USD ($)
 3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Dec. 31, 2022
Revenue from Contract with Customer, Including Assessed Tax $ 3,124,000 $ 3,273,000  
Avenova Direct [Member]      
Revenue from Contract with Customer, Including Assessed Tax 1,600,000 1,800,000  
DERMAdoctor [Member]      
Contract with Customer, Liability 300,000   $ 200,000
Revenue from Contract with Customer, Including Assessed Tax 785,000 1,043,000  
McKesson Corporation [Member] | Avenova Product [Member]      
Contract with Customer, Liability, Revenue Recognized 92,000 199,000  
McKesson Corporation [Member] | Avenova Product [Member] | Accounts Payable and Accrued Liabilities [Member]      
Contract with Customer, Liability 1,500,000   1,600,000
McKesson Corporation [Member] | Avenova Product [Member] | Prepaid Expenses and Other Current Assets [Member]      
Contract with Customer, Rebate Liability, Current 8   $ 0
Costco and Others [Member] | DERMAdoctor [Member]      
Revenue from Contract with Customer, Including Assessed Tax $ 100,000 $ 200,000