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Note 21 - Subsequent Event (Details Textual) |  |  | 12 Months Ended |  |  |  |  |
--- | --- | --- | --- | --- | --- | --- | --- | ---
Mar. 24, 2024 USD ($) $ / shares shares | Oct. 29, 2021 shares | Dec. 31, 2023 USD ($) $ / shares shares | Dec. 31, 2022 USD ($) $ / shares shares | Mar. 14, 2024 USD ($) | Jan. 29, 2024 $ / shares | Jan. 09, 2024 $ / shares | Apr. 27, 2023 $ / shares | Dec. 31, 2021 $ / shares
Goodwill and Intangible Asset Impairment | $ |  |  | $ 2,593,000 | $ 6,737,000 |  |  |  |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) |  |  | $ 1.82 | $ 7.7 |  |  |  |  | $ 57.13
Preferred Stock, Convertible, Shares Issuable (in shares) | shares |  |  | 1,000 |  |  |  |  |  |
DERMAdoctor [Member] |  |  |  |  |  |  |  |  |
Goodwill and Intangible Asset Impairment | $ |  |  | $ 2,600,000 | $ 6,700,000 |  |  |  |  |
Subsequent Event [Member] | Unsecured Convertible Notes [Member] |  |  |  |  |  |  |  |  |
Debt Instrument, Face Amount | $ | $ 525,000 |  |  |  |  |  |  |  |
Debt Instrument, Convertible, Number of Equity Instruments | 3,750,000 |  |  |  |  |  |  |  |
Subsequent Event [Member] | Series D Warrants [Member] |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) | shares | 1,000,000 |  |  |  |  |  |  |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ 0.14 |  |  |  |  |  |  |  |
Subsequent Event [Member] | DERMAdoctor [Member] | New Age Investments [Member] |  |  |  |  |  |  |  |  |
Disposal Group, Including Discontinued Operation, Consideration | $ |  |  |  |  | $ 1,100,000 |  |  |  |
Subsequent Event [Member] | DERMAdoctor [Member] | New Age Investments [Member] |  |  |  |  |  |  |  |  |
Investment Owned, Net Assets, Percentage |  |  |  |  | 100.00% |  |  |  |
Series B Preferred Stock [Member] |  |  |  |  |  |  |  |  |
Preferred Stock, Convertible, Conversion Price (in dollars per share) |  |  |  |  |  |  |  | $ 6.3 |
Series B Preferred Stock [Member] | Subsequent Event [Member] |  |  |  |  |  |  |  |  |
Preferred Stock, Convertible, Conversion Price (in dollars per share) |  |  |  |  |  | $ 0.25 | $ 0.25 |  |
Series B Preferred Stock [Member] | The 2021 Private Placement Program [Member] |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, New Issues (in shares) | shares |  | 15,000 |  |  |  |  |  |  |
Preferred Stock, Convertible, Conversion Price (in dollars per share) |  |  | $ 0.25 | $ 6.3 |  |  |  |  |
Preferred Stock, Convertible, Shares Issuable (in shares) | shares |  |  | 22,428,000 | 1,847,580 |  |  |  |  |
Series C Preferred Stock [Member] |  |  |  |  |  |  |  |  |
Preferred Stock, Convertible, Conversion Price (in dollars per share) |  |  | $ 0.25 |  |  |  |  | $ 6.3 |
Preferred Stock, Convertible, Conversion Ratio |  |  | 4,000 |  |  |  |  |  |
Series C Preferred Stock [Member] | Subsequent Event [Member] |  |  |  |  |  |  |  |  |
Preferred Stock, Convertible, Conversion Price (in dollars per share) | $ 0.14 |  |  |  |  |  |  |  |
Preferred Stock, Convertible, Conversion Ratio | 7,143 |  |  |  |  |  |  |  |
Preferred Stock, Convertible, Shares Issuable (in shares) | shares | 2,787,841 |  |  |  |  |  |  |  |

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