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Note 21 - Subsequent Event (Details Textual)
 12 Months Ended
Mar. 24, 2024
USD ($)
$ / shares
shares
Oct. 29, 2021
shares
Dec. 31, 2023
USD ($)
$ / shares
shares
Dec. 31, 2022
USD ($)
$ / shares
shares
Mar. 14, 2024
USD ($)
Jan. 29, 2024
$ / shares
Jan. 09, 2024
$ / shares
Apr. 27, 2023
$ / shares
Dec. 31, 2021
$ / shares
Goodwill and Intangible Asset Impairment | $     $ 2,593,000 $ 6,737,000          
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share)     $ 1.82 $ 7.7         $ 57.13
Preferred Stock, Convertible, Shares Issuable (in shares) | shares     1,000            
DERMAdoctor [Member]                  
Goodwill and Intangible Asset Impairment | $     $ 2,600,000 $ 6,700,000          
Subsequent Event [Member] | Unsecured Convertible Notes [Member]                  
Debt Instrument, Face Amount | $ $ 525,000                
Debt Instrument, Convertible, Number of Equity Instruments 3,750,000                
Subsequent Event [Member] | Series D Warrants [Member]                  
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) | shares 1,000,000                
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) $ 0.14                
Subsequent Event [Member] | DERMAdoctor [Member] | New Age Investments [Member]                  
Disposal Group, Including Discontinued Operation, Consideration | $         $ 1,100,000        
Subsequent Event [Member] | DERMAdoctor [Member] | New Age Investments [Member]                  
Investment Owned, Net Assets, Percentage         100.00%        
Series B Preferred Stock [Member]                  
Preferred Stock, Convertible, Conversion Price (in dollars per share)               $ 6.3  
Series B Preferred Stock [Member] | Subsequent Event [Member]                  
Preferred Stock, Convertible, Conversion Price (in dollars per share)           $ 0.25 $ 0.25    
Series B Preferred Stock [Member] | The 2021 Private Placement Program [Member]                  
Stock Issued During Period, Shares, New Issues (in shares) | shares   15,000              
Preferred Stock, Convertible, Conversion Price (in dollars per share)     $ 0.25 $ 6.3          
Preferred Stock, Convertible, Shares Issuable (in shares) | shares     22,428,000 1,847,580          
Series C Preferred Stock [Member]                  
Preferred Stock, Convertible, Conversion Price (in dollars per share)     $ 0.25         $ 6.3  
Preferred Stock, Convertible, Conversion Ratio     4,000            
Series C Preferred Stock [Member] | Subsequent Event [Member]                  
Preferred Stock, Convertible, Conversion Price (in dollars per share) $ 0.14                
Preferred Stock, Convertible, Conversion Ratio 7,143                
Preferred Stock, Convertible, Shares Issuable (in shares) | shares 2,787,841