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Note 11 - Common Stock Warrants - Warrants Outstanding (Details) - $ / shares shares in Thousands | Mar. 31, 2024 | Mar. 24, 2024 | Dec. 31, 2023 | Dec. 21, 2023 | May 01, 2023 | Mar. 31, 2023 | Dec. 31, 2022 | Nov. 10, 2022 | Nov. 30, 2021 | Jul. 31, 2020
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Exercise price (in dollars per share) | $ 1.6 |  | $ 1.82 |  |  | $ 7.7 | $ 7.7 |  |  |
Warrants outstanding (in shares) | 8,382,447 |  | 7,382,447 |  |  | 2,305,519 | 2,305,519 |  |  |
The 2019 Ladenburg Warrants [Member] |  |  |  |  |  |  |  |  |  |
Exercise price (in dollars per share) | $ 34.65 |  |  |  |  |  |  |  |  |
Expiration date | Aug. 08, 2024 |  |  |  |  |  |  |  |  |
Warrants outstanding (in shares) | 4,799 |  |  |  |  |  |  |  |  |
The July 2020 Warrants [Member] |  |  |  |  |  |  |  |  |  |
Exercise price (in dollars per share) | $ 57.75 |  |  |  |  |  |  |  |  | $ 57.75
Expiration date | Jan. 22, 2026 |  |  |  |  |  |  |  |  |
Warrants outstanding (in shares) | 59,960 |  |  |  |  |  |  |  |  |
The Amended July 2020 Warrants [Member] |  |  |  |  |  |  |  |  |  |
Exercise price (in dollars per share) | $ 1.5 |  |  |  |  |  |  |  |  |
Expiration date | Jan. 22, 2026 |  |  |  |  |  |  |  |  |
Warrants outstanding (in shares) | 77,145 |  |  |  |  |  |  |  |  |
TLF Bio Innovation 2021 Warrants [Member] |  |  |  |  |  |  |  |  |  |
Exercise price (in dollars per share) | $ 23.51 |  |  |  |  |  |  |  |  |
Expiration date | Jan. 15, 2026 |  |  |  |  |  |  |  |  |
Warrants outstanding (in shares) | 429 |  |  |  |  |  |  |  |  |
The November 2021 Warrants [Member] |  |  |  |  |  |  |  |  |  |
Exercise price (in dollars per share) | $ 6.3 |  |  |  |  |  |  |  | $ 18.55 |
Expiration date | Sep. 11, 2028 |  |  |  |  |  |  |  |  |
Warrants outstanding (in shares) | 267,858 |  |  |  |  |  |  |  |  |
The Amended November 2021 Warrants [Member] |  |  |  |  |  |  |  |  |  |
Exercise price (in dollars per share) | $ 1.5 |  |  |  |  |  |  |  |  |
Expiration date | Sep. 11, 2028 |  |  |  |  |  |  |  |  |
Warrants outstanding (in shares) | 535,716 |  |  |  |  |  |  |  |  |
The September 2022 Warrants [Member] |  |  |  |  |  |  |  |  |  |
Exercise price (in dollars per share) | $ 6.3 |  |  |  |  |  |  |  |  |
Expiration date | Sep. 11, 2028 |  |  |  |  |  |  |  |  |
Warrants outstanding (in shares) | 89,286 |  |  |  |  |  |  |  |  |
The Amended September 2022 Warrants [Member] |  |  |  |  |  |  |  |  |  |
Exercise price (in dollars per share) | $ 1.5 |  |  |  |  |  |  |  |  |
Expiration date | Sep. 11, 2028 |  |  |  |  |  |  |  |  |
Warrants outstanding (in shares) | 238,574 |  |  |  |  |  |  |  |  |
The November 2022 A-1 Warrants [Member] |  |  |  |  |  |  |  |  |  |
Exercise price (in dollars per share) | $ 6.3 |  |  |  |  |  |  | $ 6.3 |  |
Expiration date | Nov. 20, 2028 |  |  |  |  |  |  |  |  |
Warrants outstanding (in shares) | 79,366 |  |  |  |  |  |  |  |  |
The Amended November 2022 A-1 Warrants [Member] |  |  |  |  |  |  |  |  |  |
Exercise price (in dollars per share) | $ 1.5 |  |  |  |  |  |  |  |  |
Expiration date | Nov. 20, 2028 |  |  |  |  |  |  |  |  |
Warrants outstanding (in shares) | 436,510 |  |  |  |  |  |  |  |  |
The November 2022 A-2 Warrants [Member] |  |  |  |  |  |  |  |  |  |
Exercise price (in dollars per share) | $ 6.3 |  |  |  |  |  |  | $ 6.3 |  |
Expiration date | May 20, 2024 |  |  |  |  |  |  |  |  |
Warrants outstanding (in shares) | 79,366 |  |  |  |  |  |  |  |  |
The Amended November 2022 A-2 Warrants [Member] |  |  |  |  |  |  |  |  |  |
Exercise price (in dollars per share) | $ 1.5 |  |  |  |  |  |  |  |  |
Expiration date | May 20, 2024 |  |  |  |  |  |  |  |  |
Warrants outstanding (in shares) | 436,510 |  |  |  |  |  |  |  |  |
The May 2023 B-1 Warrants [Member] |  |  |  |  |  |  |  |  |  |
Exercise price (in dollars per share) | $ 1.3 |  |  | $ 1.3 | $ 1.3 |  |  |  |  |
Expiration date | Jun. 09, 2028 |  |  |  |  |  |  |  |  |
Warrants outstanding (in shares) | 1,903,848 |  |  |  |  |  |  |  |  |
The May 2023 B-2 Warrants [Member] |  |  |  |  |  |  |  |  |  |
Exercise price (in dollars per share) | $ 1.3 |  |  |  | $ 1.3 |  |  |  |  |
Expiration date | Jun. 09, 2025 |  |  |  |  |  |  |  |  |
Warrants outstanding (in shares) | 644,232 |  |  |  |  |  |  |  |  |
The December 2023 Warrants [Member] |  |  |  |  |  |  |  |  |  |
Exercise price (in dollars per share) | $ 0.25 |  |  |  |  |  |  |  |  |
Expiration date | Jun. 21, 2029 |  |  |  |  |  |  |  |  |
Warrants outstanding (in shares) | 2,528,848 |  |  |  |  |  |  |  |  |
March 2024 Warrant [Member] |  |  |  |  |  |  |  |  |  |
Exercise price (in dollars per share) | $ 0.14 | $ 0.14 |  |  |  |  |  |  |  |
Warrants outstanding (in shares) | 1,000,000 |  |  |  |  |  |  |  |  |

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