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Note 11 - Common Stock Warrants - Warrants Outstanding (Details) - $ / shares shares in Thousands	Mar. 31, 2024	Mar. 24, 2024	Dec. 31, 2023	Dec. 21, 2023	May 01, 2023	Mar. 31, 2023	Dec. 31, 2022	Nov. 10, 2022	Nov. 30, 2021	Jul. 31, 2020
Exercise price (in dollars per share)	$ 1.6		$ 1.82			$ 7.7	$ 7.7
Warrants outstanding (in shares)	8,382,447		7,382,447			2,305,519	2,305,519
The 2019 Ladenburg Warrants [Member]
Exercise price (in dollars per share)	$ 34.65
Expiration date	Aug. 08, 2024
Warrants outstanding (in shares)	4,799
The July 2020 Warrants [Member]
Exercise price (in dollars per share)	$ 57.75									$ 57.75
Expiration date	Jan. 22, 2026
Warrants outstanding (in shares)	59,960
The Amended July 2020 Warrants [Member]
Exercise price (in dollars per share)	$ 1.5
Expiration date	Jan. 22, 2026
Warrants outstanding (in shares)	77,145
TLF Bio Innovation 2021 Warrants [Member]
Exercise price (in dollars per share)	$ 23.51
Expiration date	Jan. 15, 2026
Warrants outstanding (in shares)	429
The November 2021 Warrants [Member]
Exercise price (in dollars per share)	$ 6.3								$ 18.55
Expiration date	Sep. 11, 2028
Warrants outstanding (in shares)	267,858
The Amended November 2021 Warrants [Member]
Exercise price (in dollars per share)	$ 1.5
Expiration date	Sep. 11, 2028
Warrants outstanding (in shares)	535,716
The September 2022 Warrants [Member]
Exercise price (in dollars per share)	$ 6.3
Expiration date	Sep. 11, 2028
Warrants outstanding (in shares)	89,286
The Amended September 2022 Warrants [Member]
Exercise price (in dollars per share)	$ 1.5
Expiration date	Sep. 11, 2028
Warrants outstanding (in shares)	238,574
The November 2022 A-1 Warrants [Member]
Exercise price (in dollars per share)	$ 6.3							$ 6.3
Expiration date	Nov. 20, 2028
Warrants outstanding (in shares)	79,366
The Amended November 2022 A-1 Warrants [Member]
Exercise price (in dollars per share)	$ 1.5
Expiration date	Nov. 20, 2028
Warrants outstanding (in shares)	436,510
The November 2022 A-2 Warrants [Member]
Exercise price (in dollars per share)	$ 6.3							$ 6.3
Expiration date	May 20, 2024
Warrants outstanding (in shares)	79,366
The Amended November 2022 A-2 Warrants [Member]
Exercise price (in dollars per share)	$ 1.5
Expiration date	May 20, 2024
Warrants outstanding (in shares)	436,510
The May 2023 B-1 Warrants [Member]
Exercise price (in dollars per share)	$ 1.3			$ 1.3	$ 1.3
Expiration date	Jun. 09, 2028
Warrants outstanding (in shares)	1,903,848
The May 2023 B-2 Warrants [Member]
Exercise price (in dollars per share)	$ 1.3				$ 1.3
Expiration date	Jun. 09, 2025
Warrants outstanding (in shares)	644,232
The December 2023 Warrants [Member]
Exercise price (in dollars per share)	$ 0.25
Expiration date	Jun. 21, 2029
Warrants outstanding (in shares)	2,528,848
March 2024 Warrant [Member]
Exercise price (in dollars per share)	$ 0.14	$ 0.14
Warrants outstanding (in shares)	1,000,000

X

- Definition

Exercise price per share or per unit of warrants or rights outstanding.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 505
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 3
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147481112/505-10-50-3

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- Definition

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+ References

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- Definition

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+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 820
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 2
-Subparagraph (bbb)(2)(i)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482106/820-10-50-2

Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 820
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 2
-Subparagraph (bbb)(2)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482106/820-10-50-2

Reference 3: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 820
-SubTopic 10
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-Section 50
-Paragraph 2
-Subparagraph (bbb)(1)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482106/820-10-50-2

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