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Note 14 - Common Stock Warrants - Warrants Outstanding (Details) - $ / shares shares in Thousands	Dec. 31, 2024	Jul. 26, 2024	May 30, 2024	Mar. 31, 2024	Dec. 31, 2023	May 31, 2023	Dec. 31, 2022	Nov. 10, 2022	Nov. 30, 2021	Jul. 31, 2020
Exercise Price (in dollars per share)	$ 1.41				$ 50.96		$ 269.54
Warrants outstanding (in shares)	10,836,275				210,946		65,886
The July 2020 Warrants [Member]
Exercise Price (in dollars per share)	$ 2,021.25		$ 2,021.25							$ 57.75
Expiration Date	Jan. 22, 2026
Warrants outstanding (in shares)	1,714
The Amended July 2020 Warrants [Member]
Exercise Price (in dollars per share)	$ 52.5		52.5
Expiration Date	Jan. 22, 2026
Warrants outstanding (in shares)	2,206
TLF Bio Innovation 2021 Warrants [Member]
Exercise Price (in dollars per share)	$ 822.96
Expiration Date	Jan. 15, 2026
Warrants outstanding (in shares)	13
The November 2021 Warrants [Member]
Exercise Price (in dollars per share)	$ 220.5		649.25						$ 18.55
Expiration Date	Sep. 11, 2028
Warrants outstanding (in shares)	7,654
The Amended November 2021 Warrants [Member]
Exercise Price (in dollars per share)	$ 52.5
Expiration Date	Sep. 11, 2028
Warrants outstanding (in shares)	15,308
The September 2022 Warrants [Member]
Exercise Price (in dollars per share)	$ 220.5
Expiration Date	Sep. 11, 2028
Warrants outstanding (in shares)	2,552
The Amended September 2022 Warrants [Member]
Exercise Price (in dollars per share)	$ 52.5
Expiration Date	Sep. 11, 2028
Warrants outstanding (in shares)	1,715
The November 2022 A-1 Warrants [Member]
Exercise Price (in dollars per share)	$ 220.5		220.5			$ 52.5		$ 6.3
Expiration Date	Nov. 20, 2028
Warrants outstanding (in shares)	2,268
The December 2023 Warrants [Member]
Exercise Price (in dollars per share)	$ 8.75		8.75		$ 0.25
Expiration Date	Jun. 21, 2029
Warrants outstanding (in shares)	72,256
March 2024 Warrant [Member]
Exercise Price (in dollars per share)	$ 4.9		$ 4.9	$ 0.14
Expiration Date	Mar. 24, 2029
Warrants outstanding (in shares)	28,572
June 2024 Warrant [Member]
Exercise Price (in dollars per share)	$ 2.57
Expiration Date	Dec. 17, 2029
Warrants outstanding (in shares)	90,381
Series F-1 Warrants [Member]
Exercise Price (in dollars per share)	$ 0.66	$ 1.1
Expiration Date	Jul. 30, 2029
Warrants outstanding (in shares)	3,537,212
Series F-2 Warrants [Member]
Exercise Price (in dollars per share)	$ 0.66	1.1
Expiration Date	Jan. 29, 2025
Warrants outstanding (in shares)	3,537,212
Series F-3 Warrants [Member]
Exercise Price (in dollars per share)	$ 0.66	$ 1.1
Expiration Date	Jul. 29, 2025
Warrants outstanding (in shares)	3,537,212

X

- Definition

Exercise price per share or per unit of warrants or rights outstanding.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 505
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 3
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147481112/505-10-50-3

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- Definition

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+ References

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- Definition

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+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 820
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 2
-Subparagraph (bbb)(2)(i)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482106/820-10-50-2

Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 820
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 2
-Subparagraph (bbb)(2)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482106/820-10-50-2

Reference 3: http://www.xbrl.org/2009/role/commonPracticeRef
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-Paragraph 2
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-Publisher FASB
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