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Note 10 - Common Stock Warrants and Warrant Liabilities (Tables) | 3 Months Ended
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Mar. 31, 2026
Notes Tables |
Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block] |
|  |  | July 2020 Warrants |  |  | TLF Warrants |  |  | November 2021 Warrants |  |  | September 2022 Warrants |  |  | November 2022 A-1 Warrants |  |  | December 2023 Warrants |  |  | June 2024 Warrants |  |  | July 2024 Series F-1 Warrants |  |  | October 2025 Pre-Funded Warrants* |  |  | January 2026 Pre- Funded Warrants |  |  | Total Warrants |
December 31, 2025 |  |  |  | 784 |  |  |  | 3 |  |  |  | 2,832 |  |  |  | 332 |  |  |  | 454 |  |  |  | 5,341 |  |  |  | 4,511 |  |  |  | 2,900 |  |  |  | 1,081,082 |  |  |  | - |  |  |  | 1,098,239 |
Pre-Funded Warrants granted |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | 167,539,227 |  |  |  | 167,539,227 |
Warrants exercised |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | (5,341 | ) |  |  | (4,511 | ) |  |  | - |  |  |  | - |  |  |  | - |  |  |  | (9,852 | )
Warrants expired |  |  |  | (784 | ) |  |  | (3 | ) |  |  | - |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | (787 | )
Warrants issued for 5:1 reverse stock split due to rounding feature |  |  |  | - |  |  |  | - |  |  |  | 3 |  |  |  | 1 |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | 4 |
March 31, 2026 |  |  |  | - |  |  |  | - |  |  |  | 2,835 |  |  |  | 333 |  |  |  | 454 |  |  |  | - |  |  |  | - |  |  |  | 2,900 |  |  |  | 1,081,082 |  |  |  | 167,539,227 |  |  |  | 168,626,831 |
Weighted Average Price per share at March 31, 2026 |  |  | expired |  |  | expired |  |  | $ | 557.65 |  |  | $ | 1,102.50 |  |  | $ | 1,102.50 |  |  | expired |  |  | expired |  |  | $ | 3.30 |  |  | $ | 0.002385 |  |  | $ | 0.05 |  |  | $ | 0.06 |
Expiration Date |  |  | expired |  |  | expired |  |  | September 11, 2028 |  |  | September 11, 2028 |  |  | November 20, 2028 |  |  | expired |  |  | expired |  |  | July 30, 2029 |  |  | Do not expire |  |  | Do not expire |  |  |  |  |
* |  |  | exercisable for an aggregate of 22,664,040 shares of common stock |
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block] |
Warrant liabilities as of December 31, 2025 |  | $ | 639,071 |
Fair value of January 2026 Pre-Funded Warrants upon issuance |  |  | 5,436,649 |
Decrease in fair value of warrant liabilities |  |  | (5,837,607 | )
Reclassification of January 2026 Pre-Funded Warrant liabilities to equity during period |  |  | (204,398 | )
Warrant liabilities as of March 31, 2026 |  | $ | 33,715 |

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- Definition Tabular disclosure of the fair value measurement of liabilities using significant unobservable inputs (Level 3), a reconciliation of the beginning and ending balances, separately presenting changes attributable to the following: (1) total gains or losses for the period (realized and unrealized), segregating those gains or losses included in earnings (or changes in net assets), and gains or losses recognized in other comprehensive income (loss) and a description of where those gains or losses included in earnings (or changes in net assets) are reported in the statement of income (or activities); (2) purchases, sales, issues, and settlements (each type disclosed separately); and (3) transfers in and transfers out of Level 3 (for example, transfers due to changes in the observability of significant inputs) by class of liability. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 820 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (d) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482106/820-10-50-2 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 820 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 3 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482106/820-10-50-3 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Topic 820 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482106/820-10-50-2 + Details
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- Definition Tabular disclosure of warrants or rights issued. Warrants and rights outstanding are derivative securities that give the holder the right to purchase securities (usually equity) from the issuer at a specific price within a certain time frame. Warrants are often included in a new debt issue to entice investors by a higher return potential. The main difference between warrants and call options is that warrants are issued and guaranteed by the company, whereas options are exchange instruments and are not issued by the company. Also, the lifetime of a warrant is often measured in years, while the lifetime of a typical option is measured in months. Disclose the title of issue of securities called for by warrants and rights outstanding, the aggregate amount of securities called for by warrants and rights outstanding, the date from which the warrants or rights are exercisable, and the price at which the warrant or right is exercisable. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 505 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 3 -Publisher FASB -URI https://asc.fasb.org/1943274/2147481112/505-10-50-3 + Details
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