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Organization and Summary of Significant Accounting Policies - Additional Information (Details) - USD ($) $ in Thousands | 6 Months Ended |  |
--- | --- | --- | ---
Jun. 30, 2015 | Jun. 30, 2014 | Dec. 31, 2014 | Dec. 31, 2013
Debt Instrument [Line Items] |  |  |  |
Net loss | $ 11,314 | $ 17,952 |  |
Cash used in operations | 5,323 | 8,405 |  |
Accumulated deficit | 183,940 |  | $ 172,505 |
Cash balance (not less than $9.0 million) | 12,394 | $ 11,550 | $ 18,247 | $ 2,279
Hercules Term Loan, Liquidity Covenant |  |  |  |
Debt Instrument [Line Items] |  |  |  |
Cash balance (not less than $9.0 million) | $ 9,000 |  |  |

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