<SEC-DOCUMENT>0001415889-22-012022.txt : 20221205
<SEC-HEADER>0001415889-22-012022.hdr.sgml : 20221205
<ACCEPTANCE-DATETIME>20221205111623
ACCESSION NUMBER:		0001415889-22-012022
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20221129
FILED AS OF DATE:		20221205
DATE AS OF CHANGE:		20221205

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Hawryluk Matthew
		CENTRAL INDEX KEY:			0001754470

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-36790
		FILM NUMBER:		221444112

	MAIL ADDRESS:	
		STREET 1:		C/O GRITSTONE ONCOLOGY, INC.
		STREET 2:		5858 HORTON STREET, SUITE 210
		CITY:			EMERYVILLE
		STATE:			CA
		ZIP:			94608

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Predictive Oncology Inc.
		CENTRAL INDEX KEY:			0001446159
		STANDARD INDUSTRIAL CLASSIFICATION:	ORTHOPEDIC, PROSTHETIC & SURGICAL APPLIANCES & SUPPLIES [3842]
		IRS NUMBER:				331007393
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		2915 COMMERS DRIVE,
		STREET 2:		SUITE 900
		CITY:			EAGAN
		STATE:			MN
		ZIP:			55121
		BUSINESS PHONE:		651-389-4800

	MAIL ADDRESS:	
		STREET 1:		2915 COMMERS DRIVE,
		STREET 2:		SUITE 900
		CITY:			EAGAN
		STATE:			MN
		ZIP:			55121

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Precision Therapeutics Inc.
		DATE OF NAME CHANGE:	20180314

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Precision Therapeutic Inc.
		DATE OF NAME CHANGE:	20180208

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Skyline Medical Inc.
		DATE OF NAME CHANGE:	20130807
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>form3-12052022_041213.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2022-11-29</periodOfReport>

    <noSecuritiesOwned>1</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001446159</issuerCik>
        <issuerName>Predictive Oncology Inc.</issuerName>
        <issuerTradingSymbol>POAI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001754470</rptOwnerCik>
            <rptOwnerName>Hawryluk Matthew</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>2915 COMMERS DRIVE, SUITE 900</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>EAGAN</rptOwnerCity>
            <rptOwnerState>MN</rptOwnerState>
            <rptOwnerZipCode>55121</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>true</isDirector>
            <isOfficer>false</isOfficer>
            <isTenPercentOwner>false</isTenPercentOwner>
            <isOther>false</isOther>
            <officerTitle></officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable></nonDerivativeTable>

    <derivativeTable></derivativeTable>

    <footnotes></footnotes>

    <remarks>Exhibit 24.1 Power of Attorney filed herewith.</remarks>

    <ownerSignature>
        <signatureName>/s/ Bob Myers, Attorney-in-Fact</signatureName>
        <signatureDate>2022-12-05</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>ex24-12052022_041213.htm
<TEXT>
<!DOCTYPE html PUBLIC "-//IETF//DTD HTML//EN">
<html><head><title>ex24-12052022_041213.htm</title></head><body style="margin-top:0;font-family:Times New Roman; font-size:10pt; color:#000000">
<p style="margin:0px; font-size:11pt" align="center"><b>LIMITED POWER OF ATTORNEY</b></p>
<p style="margin-top:0px; margin-bottom:22px; font-size:11pt" align="center">For Executing Form ID and Forms, 3, 4, 5 and 144</p>
<p style="margin-top:0px; margin-bottom:14.667px; text-indent:48px; font-size:11pt" align="justify">The undersigned hereby appoints Raymond F. Vennare and Robert L. Myers, as the true and lawful attorneys-in-fact, signing singly, for the undersigned, for such period of time that the undersigned is required to file reports pursuant to Section 16(a) of the Securities Exchange Act of 1934, as amended (the <font style="font-family:Arial Unicode MS,Times New Roman">&ldquo;</font>Exchange Act<font style="font-family:Arial Unicode MS,Times New Roman">&rdquo;</font>), or Rule&nbsp;144 of the Securities Act of 1933, as amended (the <font style="font-family:Arial Unicode MS,Times New Roman">&ldquo;</font>Securities Act<font style="font-family:Arial Unicode MS,Times New Roman">&rdquo;</font>), due to the undersigned<font style="font-family:Arial Unicode MS,Times New Roman">&rsquo;</font>s affiliation with <b>Predictive Oncology Inc.</b>, a Delaware corporation (the <font style="font-family:Arial Unicode MS,Times New Roman">&ldquo;</font>Company<font style="font-family:Arial Unicode MS,Times New Roman">&rdquo;</font>), unless earlier revoked by the undersigned in a signed writing delivered to the foregoing attorneys-in-fact, to: </p>
<p style="margin-top:0px; margin-bottom:-2px; text-indent:48px; width:96px; font-size:12pt; float:left">(1)</p>
<p style="margin-top:0px; margin-bottom:14.667px; padding-left:96px; text-indent:-2px; font-size:11pt" align="justify">execute for and on behalf of the undersigned Form ID (Uniform Application for Access Codes to file on EDGAR) and Forms 3, 4, 5 and 144 and any amendments to previously filed forms in accordance with Section 16(a) of the Exchange Act or Rule&nbsp;144 of the Securities Act and the rules thereunder.</p>
<p style="margin-top:0px; margin-bottom:-2px; text-indent:48px; width:96px; font-size:12pt; clear:left; float:left">(2)</p>
<p style="margin-top:0px; margin-bottom:14.667px; padding-left:96px; text-indent:-2px; font-size:11pt" align="justify">do and perform any and all acts for and on behalf of the undersigned which may be necessary or desirable to complete the execution of any such Form ID and Forms 3, 4, 5 and 144 and the timely filing of such form with the United States Securities and Exchange Commission and any other authority as required by law; and</p>
<p style="margin-top:0px; margin-bottom:-2px; text-indent:48px; width:96px; font-size:12pt; clear:left; float:left">(3)</p>
<p style="margin-top:0px; margin-bottom:14.667px; padding-left:96px; text-indent:-2px; font-size:11pt" align="justify">take any other action of any type whatsoever in connection with the foregoing which, in the opinion of such attorney-in-fact, may be of benefit to, in the best interest of, or legally required by, the undersigned, it being understood that the documents executed by such attorney-in-fact on behalf of the undersigned pursuant to this Limited Power of Attorney shall be in such form and shall contain such terms and conditions as such attorney-in-fact may approve in his discretion.</p>
<p style="margin-top:0px; margin-bottom:14.667px; text-indent:48px; font-size:11pt; clear:left" align="justify">The undersigned hereby grants to each such attorney-in-fact full power and authority to do and perform all and every act and thing whatsoever requisite, necessary and proper to be done in the exercise of any of the rights and powers herein granted, as fully to all intents and purposes as the undersigned could do if personally present, with full power of substitution or revocation, hereby ratifying and confirming all that such attorney-in-fact, or his substitute or substitutes, shall lawfully do or cause to be done by virtue of this Limited Power of Attorney and the rights and powers herein granted. &nbsp;The undersigned acknowledges that the foregoing attorneys-in-fact, in serving in such capacity at the request of the undersigned, are not assuming any of the undersigned<font style="font-family:Arial Unicode MS,Times New Roman">&rsquo;</font>s responsibilities to comply with Section 16 of the Exchange Act or Rule 144 of the Securities Act.</p>
<p style="margin-top:0px; margin-bottom:14.667px; text-indent:48px; font-size:11pt" align="justify">This Limited Power of Attorney shall remain in full force and effect until the undersigned is no longer required to file Forms 144, Forms 3, 4 and 5 with respect to the undersigned<font style="font-family:Arial Unicode MS,Times New Roman">&rsquo;</font>s holdings of and transactions in securities issued by the Company unless earlier revoked by the undersigned in a writing delivered to the foregoing attorneys-in-fact.</p>
<p style="margin-top:0px; margin-bottom:14.667px; text-indent:48px; font-size:11pt" align="justify">IN WITNESS WHEREOF, the undersigned has caused this Limited Power of Attorney to be executed as of this _2__ day of __December__, 2022.</p>
<p style="margin:0px" align="justify"><br></p>
<p style="margin:0px" align="justify"><br></p>
<p style="margin:0px; padding-left:288px; font-size:11pt" align="justify"><u>/s/Matthew Hawryluk</u></p>
<p style="margin:0px; padding-left:288px; font-size:11pt" align="justify">Signature</p>
<p style="margin:0px" align="justify"><br></p>
<p style="margin:0px; padding-left:288px; font-size:11pt" align="justify"><u>Matthew Hawryluk</u></p>
<p style="margin:0px; padding-left:288px; font-size:11pt" align="justify">Type or Print Name</p>
<p style="margin:0px" align="justify"><br></p>
</body></html>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
