<SEC-DOCUMENT>0001178913-21-003396.txt : 20211104
<SEC-HEADER>0001178913-21-003396.hdr.sgml : 20211104
<ACCEPTANCE-DATETIME>20211104161202
ACCESSION NUMBER:		0001178913-21-003396
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20211025
FILED AS OF DATE:		20211104
DATE AS OF CHANGE:		20211104

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Pfost Dale R
		CENTRAL INDEX KEY:			0001394663

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38807
		FILM NUMBER:		211380065

	MAIL ADDRESS:	
		STREET 1:		ACUITY PHARMACEUTICALS INC
		STREET 2:		3701 MARKET STREET
		CITY:			PHILADELPHIA
		STATE:			PA
		ZIP:			19104

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Chemomab Therapeutics Ltd.
		CENTRAL INDEX KEY:			0001534248
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				813676773
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		KIRYAT ATIDIM, BUILDING 7
		CITY:			TEL AVIV
		STATE:			L3
		ZIP:			6158002
		BUSINESS PHONE:		972-77-331-0156

	MAIL ADDRESS:	
		STREET 1:		KIRYAT ATIDIM, BUILDING 7
		CITY:			TEL AVIV
		STATE:			L3
		ZIP:			6158002

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Anchiano Therapeutics Ltd.
		DATE OF NAME CHANGE:	20180906

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	BioCancell Ltd.
		DATE OF NAME CHANGE:	20111104
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
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<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2021-10-25</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001534248</issuerCik>
        <issuerName>Chemomab Therapeutics Ltd.</issuerName>
        <issuerTradingSymbol>CMMB</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001394663</rptOwnerCik>
            <rptOwnerName>Pfost Dale R</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>1316 JEFFERSON AVE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>NEW ORLEANS</rptOwnerCity>
            <rptOwnerState>LA</rptOwnerState>
            <rptOwnerZipCode>70115</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Chief Executive Officer</officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Option to Purchase American Depositary Shares</value>
                <footnoteId id="F1"/>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>10.05</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F2"/>
            </exerciseDate>
            <expirationDate>
                <value>2031-10-25</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>American Depositary Shares</value>
                    <footnoteId id="F1"/>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>459353</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Each American Depositary Share (ADS) represents twenty (20) ordinary shares, no par value, of the Issuer.</footnote>
        <footnote id="F2">The options vest and become exercisable over a period of four (4) years with one quarter (1/4) of the options vesting on October 25, 2022 -- the first anniversary of the grant date -- and the remainder in equal amounts over the ensuing 36 monthly periods, subject to the Reporting Person's continued service.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Matthew Rudolph, Attorney-in-Fact for Dale R. Pfost</signatureName>
        <signatureDate>2021-11-04</signatureDate>
    </ownerSignature>
</ownershipDocument>
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<DOCUMENT>
<TYPE>EX-24.1
<SEQUENCE>2
<FILENAME>exhibit_24-1.htm
<DESCRIPTION>EXHIBIT 24.1
<TEXT>
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    <div style="text-align: right; line-height: 1.25; font-family: 'Times New Roman',Times,serif; font-weight: bold;"><u>Exhibit 24.1</u><br>
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    <div style="text-align: center; line-height: 1.25; font-weight: bold;"><br>
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    <div style="text-align: center; line-height: 1.25; font-weight: bold;">POWER OF ATTORNEY</div>
    <div style="text-align: center; line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">Know all by these presents, that the undersigned hereby constitutes and appoints Matthew Rudolph, outside counsel to
      Chemomab Therapeutics Ltd. (the &#8220;Company&#8221;) with full power of substitution, signing individually, the undersigned's true and lawful attorney-in fact and agent to:</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">1.&#160;&#160;&#160;&#160;&#160;&#160;&#160;Prepare, execute in the undersigned&#8217;s name and on the undersigned's behalf, and submit to the Securities and
      Exchange Commission (the &#8220;SEC&#8221;) Form ID, Uniform Application for Access Codes to File on EDGAR, including amendments thereto, and any other documents necessary or appropriate to obtain codes and passwords enabling the undersigned to make electronic
      filings with the SEC of reports required by Section 16(a) of the Securities Exchange Act of 1934, as amended (the &#8220;Exchange Act&#8221;), or any rule or regulation thereunder;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">2.&#160;&#160;&#160;&#160;&#160;&#160;&#160;Prepare, execute in the undersigned's name and on the undersigned&#8217;s behalf, and submit to the SEC Forms 3, 4
      and 5 (including amendments thereto and joint filing agreements in connection therewith) in accordance with Section 16(a) of the Exchange Act and the rules and regulations thereunder in the undersigned's capacity as an officer, director or beneficial
      owner of more than 10% of a registered class of securities of the Company;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">3.&#160;&#160;&#160;&#160;&#160;&#160;&#160;Do and perform any and all acts for and on behalf of the undersigned that may be necessary or desirable to
      execute such Forms 3, 4, or 5, or Form ID (including any amendments thereto) and timely file such forms with the SEC, and any stock exchange, self-regulatory association or similar authority; and</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">4.&#160;&#160;&#160;&#160;&#160;&#160;&#160;Take any other action of any nature whatsoever in connection with the foregoing that, in the opinion of such
      attorney-in-fact, may be of benefit, in the best interest of, or legally required by, the undersigned, it being understood that the documents executed by such attorney-in-fact on behalf of the undersigned pursuant to this Power of Attorney shall be
      in such form and shall contain such terms and conditions as such attorney-in-fact may approve in such attorney-in-fact's discretion.</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">The undersigned hereby grants to each such attorney in fact full power and authority to do and perform any and every
      act and thing whatsoever requisite, necessary, or proper to be done in the exercise of any of the rights and powers herein granted, as fully to all intents and purposes as the undersigned might or could do if personally present, with full power of
      substitution or revocation, hereby ratifying and confirming all that such attorney in fact, or such attorney in fact&#8217;s substitute or substitutes, shall lawfully do or cause to be done by virtue of this power of attorney and the rights and powers
      herein granted. The undersigned acknowledges that the foregoing attorney-in-fact, and his substitutes, in serving in such capacity at the request of the undersigned, is not assuming (nor is the Company assuming) any of the undersigned&#8217;s
      responsibilities to comply with Section 16 of the Exchange Act.</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">&#160;</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;">This Power of Attorney shall remain in full force and effect until the earliest to occur of (a) the undersigned is no
      longer required to file Forms 3, 4 and 5 with respect to the undersigned's holdings of and transactions in securities issued by the Company, (b) revocation by the undersigned in a signed writing delivered to the foregoing attorney-in-fact or (c) as
      to any attorney-in-fact individually, until such attorney-in-fact is no longer employed by the Company.</div>
    <div style="line-height: 1.25;">&#160;</div>
    <div style="text-indent: 36pt; line-height: 1.25;">IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to be executed as of this 23<sup style="vertical-align: text-top; line-height: 1; font-size: smaller;">rd</sup> day of
      August, 2021.</div>
    <div style="text-indent: 36pt; line-height: 1.25;">&#160;</div>
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            <div style="line-height: 1.25;">By:</div>
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            <div style="line-height: 1.25;">/s/ Dale Pfost</div>
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            <div style="line-height: 1.25;">Name:</div>
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            <div style="line-height: 1.25;">Dale Pfost</div>
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