<SEC-DOCUMENT>0001178913-22-003108.txt : 20220815
<SEC-HEADER>0001178913-22-003108.hdr.sgml : 20220815
<ACCEPTANCE-DATETIME>20220815160703
ACCESSION NUMBER:		0001178913-22-003108
CONFORMED SUBMISSION TYPE:	S-8
PUBLIC DOCUMENT COUNT:		5
FILED AS OF DATE:		20220815
DATE AS OF CHANGE:		20220815
EFFECTIVENESS DATE:		20220815

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Chemomab Therapeutics Ltd.
		CENTRAL INDEX KEY:			0001534248
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				813676773
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-8
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-266868
		FILM NUMBER:		221165661

	BUSINESS ADDRESS:	
		STREET 1:		KIRYAT ATIDIM, BUILDING 7
		CITY:			TEL AVIV
		STATE:			L3
		ZIP:			6158002
		BUSINESS PHONE:		972-77-331-0156

	MAIL ADDRESS:	
		STREET 1:		KIRYAT ATIDIM, BUILDING 7
		CITY:			TEL AVIV
		STATE:			L3
		ZIP:			6158002

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Anchiano Therapeutics Ltd.
		DATE OF NAME CHANGE:	20180906

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	BioCancell Ltd.
		DATE OF NAME CHANGE:	20111104
</SEC-HEADER>
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    <div style="text-align: center; line-height: 1.25; font-weight: bold;">As filed with the Securities and Exchange Commission on August 15, 2022</div>
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    <div style="text-align: right; line-height: 1.25; font-weight: bold;">Registration&#160;No.&#160;333-&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;</div>
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    <div style="text-align: center; line-height: 1.25; font-weight: bold;">UNITED STATES</div>
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    <div style="text-align: center; line-height: 1.25; font-style: italic; font-weight: bold;">THE SECURITIES ACT OF 1933</div>
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    <div style="text-align: center; line-height: 1.25; font-family: 'Times New Roman',Times,serif; font-size: 16pt; font-weight: bold;">Chemomab Therapeutics Ltd.</div>
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    <div style="text-align: center; line-height: 1.25; font-weight: bold;">Chemomab Therapeutics, Inc.<br>
      One Kendall Square<br>
      Building 1400E<br>
      Suite 14-105<br>
      Cambridge, MA 02139<br>
      (857) 259-4622</div>
    <div style="text-align: center; line-height: 1.25; font-weight: bold;">(Name, address, including zip code, and telephone number, including area code, of agent for service)</div>
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            <div style="text-align: center; line-height: 1.25; font-family: 'Times New Roman',Times,serif; font-weight: bold;">David S. Glatt</div>
            <div style="text-align: center; line-height: 1.25; font-family: 'Times New Roman',Times,serif; font-weight: bold;">Ronen Bezalel<br>
              Jonathan M. Nathan<br>
              Meitar | Law Offices<br>
              16 Abba Hillel Rd.<br>
              Ramat Gan 5250608, Israel<br>
              +972 (3)&#160;610-3100</div>
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    <div style="line-height: 1.25;">Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a&#160;non-accelerated&#160;filer, a smaller reporting company or an emerging growth company. See the definitions of &#8220;large
      accelerated filer,&#8221; &#8220;accelerated filer,&#8221; &#8220;smaller reporting company&#8221; and &#8220;emerging growth company&#8221; in Rule&#160;12b-2&#160;of the Exchange Act of 1934, as amended.</div>
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    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <div style="line-height: 1.25;">If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to
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    <div style="text-align: center; line-height: 1.25; font-weight: bold;">EXPLANATORY NOTE</div>
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    <div style="text-align: justify; text-indent: 28.35pt; line-height: 1.25;">This Registration Statement is being filed to register an additional 10,800,000 Ordinary Shares of Chemomab Therapeutics Ltd., formerly known as Anchiano Therapeutics Ltd. (the
      &#8220;Registrant,&#8221; &#8220;we,&#8221; &#8220;our,&#8221; or &#8220;us&#8221;) issuable pursuant to the Anchiano Therapeutics Ltd. 2017 Equity-Based Incentive Plan (the &#8220;2017 Plan&#8221;), representing an automatic annual increase effective as of January 1, 2022 pursuant to the 2017 Plan.</div>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <div style="text-align: justify; text-indent: 28.35pt; line-height: 1.25;">Pursuant to Instruction E of Form S-8, the contents of our prior registration statements on Forms S-8 (File Nos. 333-232757, 333-237247 and 333-259489) are incorporated herein
      by reference, and the information required by Part II is omitted, except as supplemented by the information set forth below.</div>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <div style="text-align: justify; text-indent: 28.35pt; line-height: 1.25;">The 2017 Plan provides that the number of Ordinary Shares available for issuance under the 2017 Plan will automatically increase on January 1 of each calendar year during the
      term of the 2017 Plan by 4% of the total number of Ordinary Shares outstanding on December 31st of the immediately preceding calendar year, or such lesser number as shall be determined by the Committee (as defined therein), subject to adjustments
      required for recapitalization events (e.g. stock splits).</div>
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    <div style="text-align: center; line-height: 1.25; font-weight: bold;">PART I</div>
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    <div style="text-align: center; line-height: 1.25; font-weight: bold;">INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS</div>
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    <div style="text-align: justify; text-indent: 28.35pt; line-height: 1.25;">The information called for by Items 1 and 2 of Part I of Form&#160;S-8&#160;is not being filed with or included in this Form&#160;S-8&#160;(by incorporation by reference or otherwise) in accordance
      with the rules and regulations of the Securities and Exchange Commission (the &#8220;SEC&#8221;).</div>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <div style="text-align: justify; text-indent: 28.35pt; line-height: 1.25;">The documents containing the information specified in Part I of Form S-8 will be sent or given to participants in the 2017 Plan as specified by Rule 428(b) under the Securities
      Act.&#160;Such documents and the documents incorporated by reference herein pursuant to Item 3 of Part II hereof, taken together, constitute a prospectus that meets the requirements of Section 10(a) of the Securities Act.</div>
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    <div style="text-align: center; line-height: 1.25; font-weight: bold;">PART II</div>
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    <div style="text-align: center; line-height: 1.25; font-weight: bold;">INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</div>
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    <div style="line-height: 1.25; font-weight: bold;">Item&#160;3. Incorporation of Documents by Reference.</div>
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    <div style="text-align: justify; text-indent: 28.35pt; line-height: 1.25;">The Registrant hereby incorporates by reference in this Registration Statement the following documents:</div>
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            <div style="text-align: justify; line-height: 1.25;">(i)</div>
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          <td style="width: 95.02%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">the Registrant&#8217;s Annual Report on Form 10-K for the fiscal year ended December 31, 2021, filed with the SEC on March 30, 2022 (the &#8220;Annual Report&#8221;);</div>
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            <div style="text-align: justify; line-height: 1.25;">(ii)</div>
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            <div style="text-align: justify; line-height: 1.25;">The Company&#8217;s Quarterly Report on Form 10-Q for the quarter ended March 31, 2022, filed with the SEC on May 12, 2022;</div>
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          <td style="width: 1.64%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">&#160;</td>
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          <td style="width: 95.02%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">&#160;</td>
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            <div style="text-align: justify; line-height: 1.25;">(iii)</div>
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            <div style="text-align: justify; line-height: 1.25;">The Company&#8217;s Current Reports on Form 8-K, as filed with the Commission on May 12, 2022 (excluding information furnished pursuant to Item 2.02), June 1, 2022, June 8, 2022, June 21, 2022 and
              August 12, 2022 (excluding information furnished pursuant to Item 2.02);</div>
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          <td style="width: 1.64%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">&#160;</td>
          <td style="width: 3.34%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">&#160;</td>
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            <div style="text-align: justify; line-height: 1.25;">(iv)</div>
          </td>
          <td style="width: 95.02%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">the description of the Ordinary Shares and ADSs contained in the Registrant&#8217;s registration statement on Form S-4, filed with the SEC on&#160;January 13, 2021, and as contained in Exhibit 4.1 of
              the Annual Report, as may be further updated or amended in any amendment or report filed for such purpose; and</div>
          </td>
        </tr>
        <tr>
          <td style="width: 1.64%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 3.34%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 95.02%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 1.64%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 3.34%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">(v)</div>
          </td>
          <td style="width: 95.02%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">all other reports filed pursuant to Section 13(a) or 15(d) of the Securities Exchange Act of 1934, as amended (the &#8220;Exchange Act&#8221;), since the end of the fiscal year covered by the Annual
              Report.</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <div style="text-align: justify; text-indent: 28.35pt; line-height: 1.25;">All documents subsequently filed by the Registrant with the SEC pursuant to Section 13(a), 13(c), 14 or 15(d) of the Exchange Act, prior to the filing of a post-effective
      amendment to this Registration Statement which indicates that all securities offered hereby have been sold or which deregisters all securities then remaining unsold, shall be deemed to be incorporated by reference in this Registration Statement and
      to be a part hereof from the date of filing of such documents.</div>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <div style="text-align: justify; text-indent: 28.35pt; line-height: 1.25;">For purposes of this Registration Statement, any document or any statement contained in a document incorporated or deemed to be incorporated herein by reference shall be deemed
      to be modified or superseded to the extent that a subsequently filed document or a statement contained herein or in any other subsequently filed document which also is or is deemed to be incorporated herein by reference modifies or supersedes such
      document or such statement in such document. Any such document or such statement so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a part of this Registration Statement.</div>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <div style="line-height: 1.25; font-weight: bold;">Item&#160;4. Description of Securities.</div>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <div style="text-align: justify; text-indent: 28.35pt; line-height: 1.25;">Not applicable.</div>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <div style="line-height: 1.25; font-weight: bold;">Item&#160;5. Interests of Named Experts and Counsel.</div>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <div style="text-align: justify; text-indent: 28.35pt; line-height: 1.25;">None.</div>
    <div style="text-indent: 35.45pt; line-height: 1.25;"> <br>
    </div>
    <div style="line-height: 1.25; font-weight: bold;">Item&#160;6. Indemnification of Directors and Officers.</div>
    <div style="line-height: 1.25; font-weight: bold;"> <br>
    </div>
    <div style="text-align: justify; text-indent: 28.35pt; line-height: 1.25;">An Israeli company may indemnify an office holder in respect of certain liabilities either in advance of an event or following an event provided that a provision authorizing
      such indemnification is inserted in its articles of association. Our Articles of Association contain such a provision. An undertaking provided in advance by an Israeli company to indemnify an office holder with respect to a financial liability
      imposed on him or her in favor of another person pursuant to a judgment, settlement or arbitrator&#8217;s award approved by a court must be limited to events which in the opinion of the Board of Directors can be foreseen based on the company&#8217;s activities
      when the undertaking to indemnify is given, and to an amount or a criteria determined by the Board of Directors as reasonable under the circumstances, and such undertaking must detail the abovementioned events and amount or criteria.</div>
    <div style="text-align: justify; text-indent: 36pt; line-height: 1.25;"> <br>
    </div>
    <div style="text-align: justify; text-indent: 28.35pt; line-height: 1.25;">In addition, a company may indemnify an office holder against the following liabilities incurred for acts performed as an office holder:</div>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <table cellspacing="0" cellpadding="0" id="z55e60912a8f7479790ab452b666a8edc" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;">

        <tr>
          <td style="width: 1.16%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 1.35%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#9679;</div>
          </td>
          <td style="width: 97.5%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">reasonable litigation expenses, including attorneys&#8217; fees, incurred by the office holder as a result of an investigation or proceeding instituted against him or her by an authority authorized
              to conduct such investigation or proceeding, provided that (i) no indictment was filed against such office holder as a result of such investigation or proceeding; and (ii) no financial liability, such as a criminal penalty (as defined in the
              Companies Law), was imposed upon him or her as a substitute for the criminal proceeding as a result of such investigation or proceeding or, if such financial liability was imposed, it was imposed with respect to an offense that does not
              require proof of criminal intent or in connection with a monetary sanction; and</div>
          </td>
        </tr>
        <tr>
          <td style="width: 1.16%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 1.35%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 97.5%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 1.16%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 1.35%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#9679;</div>
          </td>
          <td style="width: 97.5%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">reasonable litigation expenses, including attorneys&#8217; fees, incurred by the office holder or imposed by a court (i) in proceedings instituted against him or her by the company, on its behalf
              or by a third party, or (ii) in connection with criminal proceedings in which the office holder was acquitted, or (iii) as a result of a conviction for a crime that does not require proof of criminal intent.</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" id="DSPFPageBreakArea">
      <div style="text-align: center;" id="DSPFPageNumberArea"><font style="font-weight: normal; font-style: normal;" id="DSPFPageNumber">- 3 -</font></div>
      <div style="page-break-after: always;" id="DSPFPageBreak">
        <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
    </div>
    <div style="text-align: justify; text-indent: 28.35pt; line-height: 1.25;">An Israeli company may insure a director or officer against the following liabilities incurred for acts performed as a director or officer:</div>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <table cellspacing="0" cellpadding="0" id="zdb832c4f948349a3b3674cc87f87b2f2" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;">

        <tr>
          <td style="width: 1.16%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 1.35%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#9679;</div>
          </td>
          <td style="width: 97.5%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">a breach of duty of care to the company or to a third party, including a breach arising out of the negligent conduct of an office holder;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 1.16%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 1.35%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 97.5%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 1.16%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 1.35%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#9679;</div>
          </td>
          <td style="width: 97.5%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">a breach of duty of loyalty to the company, provided the director or officer acted in good faith and had a reasonable basis to believe that the act would not prejudice the interests of the
              company; and</div>
          </td>
        </tr>
        <tr>
          <td style="width: 1.16%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 1.35%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 97.5%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 1.16%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 1.35%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#9679;</div>
          </td>
          <td style="width: 97.5%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">financial liabilities imposed on the office holder for the benefit of a third party.</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <div style="text-align: justify; text-indent: 28.35pt; line-height: 1.25;">An Israeli company may not, however, indemnify or insure an office holder against any of the following:</div>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <table cellspacing="0" cellpadding="0" id="zabb21eab09a94301aee3412f37ea6cf5" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;">

        <tr>
          <td style="width: 1.06%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 1.35%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#9679;</div>
          </td>
          <td style="width: 97.6%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">a breach of duty of loyalty, except to the extent that the office holder acted in good faith and had a reasonable basis to believe that the act would not prejudice the company;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 1.06%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 1.35%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 97.6%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 1.06%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 1.35%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#9679;</div>
          </td>
          <td style="width: 97.6%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">a breach of duty of care committed intentionally or recklessly, excluding a breach arising out of the negligent conduct of the office holder;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 1.06%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 1.35%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 97.6%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 1.06%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 1.35%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#9679;</div>
          </td>
          <td style="width: 97.6%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">an act or omission committed with intent to derive unlawful personal benefit; or</div>
          </td>
        </tr>
        <tr>
          <td style="width: 1.06%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 1.35%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 97.6%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 1.06%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 1.35%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#9679;</div>
          </td>
          <td style="width: 97.6%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">a fine, monetary sanction, penalty or forfeit levied against the office holder.</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <div style="text-align: justify; text-indent: 28.35pt; line-height: 1.25;">Under the Israeli Companies Law, or the Companies Law, indemnification and insurance of office holders must be approved by our compensation committee, our Board of Directors
      and, in certain circumstances, by our shareholders. We have obtained directors&#8217; and officers&#8217; liability insurance for the benefit of our office holders and intend to continue to maintain such coverage and pay all premiums thereunder to the fullest
      extent permitted by the Companies Law. In addition, we have entered into indemnification agreements with each of our directors providing them with indemnification for liabilities or expenses incurred as a result of acts performed by them in their
      capacity as our, or our subsidiaries&#8217;, directors and officers. This indemnification is limited both in terms of amount and coverage and it covers certain amounts regarding administrative proceedings insurable or indemnifiable under the Companies Law
      and our Articles of Association. In the opinion of the U.S. Securities and Exchange Commission, however, indemnification of directors and office holders for liabilities arising under the U.S. Securities Act of 1933, as amended, or the Securities Act,
      is against public policy and therefore unenforceable.</div>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <div style="line-height: 1.25; font-weight: bold;">Item&#160;7. Exemption from Registration Claimed.</div>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <div style="text-align: justify; text-indent: 28.35pt; line-height: 1.25;">Not applicable.</div>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" id="DSPFPageBreakArea">
      <div style="text-align: center;" id="DSPFPageNumberArea"><font style="font-weight: normal; font-style: normal;" id="DSPFPageNumber">- 4 -</font></div>
      <div style="page-break-after: always;" id="DSPFPageBreak">
        <hr noshade="noshade" style="border-width: 0px; clear: both; margin: 4px 0px; width: 100%; height: 2px; color: #000000; background-color: #000000;"></div>
    </div>
    <div style="line-height: 1.25; font-weight: bold;">Item&#160;8. Exhibits.</div>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <table cellspacing="0" cellpadding="0" id="z7762ce05e470409d8725f2eeffdb620f" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;">

        <tr>
          <td nowrap="nowrap" style="width: 9.85%; vertical-align: bottom; border-bottom: #000000 2px solid;">
            <div style="text-align: center; line-height: 1.25; font-weight: bold;">Exhibit</div>
            <div style="text-align: center; line-height: 1.25; font-weight: bold;">Number</div>
          </td>
          <td style="width: 2%; vertical-align: bottom; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">&#160;&#160;</div>
          </td>
          <td nowrap="nowrap" style="width: 88.16%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0); font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25; font-weight: bold;">Exhibit</div>
          </td>
        </tr>
        <tr>
          <td style="width: 9.85%; vertical-align: middle; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 90.15%; vertical-align: middle; font-family: 'Times New Roman',Times,serif;" colspan="2">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
        </tr>
        <tr>
          <td nowrap="nowrap" style="width: 9.85%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: center; line-height: 1.25;"><a href="https://www.sec.gov/Archives/edgar/data/1534248/000110465921037294/tm219877d1_ex3-1.htm">3.1</a></div>
          </td>
          <td style="width: 2%; vertical-align: bottom; font-family: 'Times New Roman',Times,serif;"><br>
          </td>
          <td style="width: 88.16%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;"><a href="https://www.sec.gov/Archives/edgar/data/1534248/000110465921037294/tm219877d1_ex3-1.htm">Amended and Restated Articles of Association (incorporated by reference to Exhibit 3.1 to the Registrant&#8217;s current
                report on Form 8-K filed with the SEC on March 17, 2021)</a></div>
          </td>
        </tr>
        <tr>
          <td style="width: 9.85%; vertical-align: middle; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 90.15%; vertical-align: middle; font-family: 'Times New Roman',Times,serif;" colspan="2"><br>
          </td>
        </tr>
        <tr>
          <td nowrap="nowrap" style="width: 9.85%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: center; line-height: 1.25;"><a href="exhibit_5-1.htm">5.1*</a></div>
          </td>
          <td style="width: 2%; vertical-align: bottom; font-family: 'Times New Roman',Times,serif;"><br>
          </td>
          <td style="width: 88.16%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;"><a href="exhibit_5-1.htm">Opinion of Meitar | Law Offices</a></div>
          </td>
        </tr>
        <tr>
          <td nowrap="nowrap" style="width: 9.85%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 2%; vertical-align: bottom; font-family: 'Times New Roman',Times,serif;"><br>
          </td>
          <td style="width: 88.16%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
        </tr>
        <tr>
          <td nowrap="nowrap" style="width: 9.85%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: center; line-height: 1.25;"><a href="exhibit_23-1.htm">23.1*</a></div>
          </td>
          <td style="width: 2%; vertical-align: bottom; font-family: 'Times New Roman',Times,serif;"><a href="exhibit_23-1.htm"><br>
            </a> </td>
          <td style="width: 88.16%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;"><a href="exhibit_23-1.htm">Consent of Somekh Chaikin, member firm of KPMG International, independent registered public accounting firm</a></div>
          </td>
        </tr>
        <tr>
          <td nowrap="nowrap" style="width: 9.85%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 2%; vertical-align: bottom; font-family: 'Times New Roman',Times,serif;"><br>
          </td>
          <td style="width: 88.16%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
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          <td nowrap="nowrap" style="width: 9.85%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: center; line-height: 1.25;"><a href="exhibit_5-1.htm">23.3*</a></div>
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          <td style="width: 2%; vertical-align: bottom; font-family: 'Times New Roman',Times,serif;"><br>
          </td>
          <td style="width: 88.16%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;"><a href="exhibit_5-1.htm">Consent of Meitar | Law Offices (included in Exhibit 5.1)</a></div>
          </td>
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        <tr>
          <td nowrap="nowrap" style="width: 9.85%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">&#160;</td>
          <td style="width: 2%; vertical-align: bottom; font-family: 'Times New Roman',Times,serif;"><br>
          </td>
          <td style="width: 88.16%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">&#160;</td>
        </tr>
        <tr>
          <td nowrap="nowrap" style="width: 9.85%; vertical-align: middle; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: center; line-height: 1.25;"><a href="#POWER">24.1*</a></div>
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          <td style="width: 2%; vertical-align: bottom; font-family: 'Times New Roman',Times,serif;"><a href="#POWER"><br>
            </a></td>
          <td style="width: 88.16%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;"><a href="#POWER">Powers of Attorney (included on signature pages hereto)</a></div>
          </td>
        </tr>
        <tr>
          <td nowrap="nowrap" style="width: 9.85%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">&#160;</td>
          <td style="width: 2%; vertical-align: bottom; font-family: 'Times New Roman',Times,serif;"><br>
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          <td style="width: 88.16%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">&#160;</td>
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        <tr>
          <td nowrap="nowrap" style="width: 9.85%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: center; line-height: 1.25;"><a href="https://www.sec.gov/Archives/edgar/data/1534248/000114420419035399/tv525340_ex99-2.htm">99.1</a></div>
          </td>
          <td style="width: 2%; vertical-align: bottom; font-family: 'Times New Roman',Times,serif;"><a href="https://www.sec.gov/Archives/edgar/data/1534248/000114420419035399/tv525340_ex99-2.htm"><br>
            </a></td>
          <td style="width: 88.16%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;"><a href="https://www.sec.gov/Archives/edgar/data/1534248/000114420419035399/tv525340_ex99-2.htm">2017 Equity-Based Incentive Plan (incorporated by reference to Exhibit 99.2 to the Registrant&#8217;s registration
                statement on Form S-8 (SEC file number 333- 232757), filed with the SEC on July 22, 2019)</a></div>
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        <tr>
          <td nowrap="nowrap" style="width: 9.85%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">&#160;</td>
          <td style="width: 2%; vertical-align: bottom; font-family: 'Times New Roman',Times,serif;"><br>
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          <td style="width: 88.16%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">&#160;</td>
        </tr>
        <tr>
          <td nowrap="nowrap" style="width: 9.85%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: center; line-height: 1.25;"><a href="exhibit_107-1.htm">107.1</a></div>
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          <td style="width: 2%; vertical-align: bottom; font-family: 'Times New Roman',Times,serif;"><br>
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          <td style="width: 88.16%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;"><a href="exhibit_107-1.htm">Filing Fee Table</a></div>
          </td>
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    </table>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
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        <tr>
          <td style="width: 3.78%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">*</div>
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          <td style="width: 96.22%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">Filed herewith.</div>
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    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <div style="line-height: 1.25; font-weight: bold;">Item&#160;9. Undertakings.</div>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
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        <tr>
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            <div style="text-align: justify; line-height: 1.25;">(a)</div>
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            <div style="text-align: justify; line-height: 1.25;">The Registrant hereby undertakes:</div>
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    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
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        <tr>
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            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
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            <div style="line-height: 1.25;">(1)</div>
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            <div style="text-align: justify; line-height: 1.25;">To file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement:</div>
          </td>
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    </table>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <table cellspacing="0" cellpadding="0" id="z6e0fe3f262dd4110a3ec9c9e0339d440" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;">

        <tr>
          <td style="width: 4%; vertical-align: middle; font-family: 'Times New Roman',Times,serif;">&#160;</td>
          <td style="width: 3%; vertical-align: middle; font-family: 'Times New Roman',Times,serif;">&#160;</td>
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            <div style="line-height: 1.25;">(i)</div>
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          <td style="width: 90%; vertical-align: middle; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">To include any prospectus required by Section&#160;10(a)(3) of the Securities Act of 1933;</div>
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    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <table cellspacing="0" cellpadding="0" id="z1fa52a3288d144c4a42ace8e2c87b1e9" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;">

        <tr>
          <td style="width: 4%; vertical-align: middle; font-family: 'Times New Roman',Times,serif;">&#160;</td>
          <td style="width: 3%; vertical-align: middle; font-family: 'Times New Roman',Times,serif;">&#160;</td>
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            <div style="line-height: 1.25;">(ii)</div>
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          <td style="width: 90%; vertical-align: middle; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">To reflect in the prospectus any facts or events arising after the effective date of the Registration Statement (or the most recent post-effective amendment thereof) which, individually or in
              the aggregate, represent a fundamental change in the information set forth in the Registration Statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities offered
              would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range may be reflected in the form of prospectus filed with the SEC pursuant to Rule 424(b) if, in the aggregate, the
              changes in volume and price represent no more than 20&#160;percent change in the maximum aggregate offering price set forth in the &#8220;Calculation of Registration Fee&#8221; table in the effective Registration Statement; and</div>
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    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
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          <td style="width: 3.89%; vertical-align: middle; font-family: 'Times New Roman',Times,serif;">&#160;</td>
          <td style="width: 2.9%; vertical-align: middle; font-family: 'Times New Roman',Times,serif;">&#160;</td>
          <td style="width: 3.31%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">(iii)</div>
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          <td style="width: 89.9%; vertical-align: middle; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">To include any material information with respect to the plan of distribution not previously disclosed in the Registration Statement or any material change to such information in the
              Registration Statement;</div>
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    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <div style="text-align: justify; line-height: 1.25;"><font style="font-style: italic;">provided, however</font><font style="font-family: 'Times New Roman',Times,serif;">, that paragraphs (a)(1)(i) and (a)(1)(ii) do not apply if the Registration
        Statement is on Form&#160;S-8,&#160;and the information required to be included in a post-effective amendment by those paragraphs is contained in reports filed with or furnished to the SEC by the Registrant pursuant to section&#160;13 or 15(d) of the Securities
        Exchange Act of 1934 that are incorporated by reference in this Registration Statement.</font></div>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
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          <td style="width: 4%; vertical-align: middle; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
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          <td style="width: 3%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">(2)</div>
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          <td style="width: 93%; vertical-align: middle; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">That, for the purpose of determining any liability under the Securities Act of 1933, each such post-effective amendment shall be deemed to be a new registration statement relating to the
              securities offered therein, and the offering of such securities at that time shall be deemed to be the initial&#160;<font style="font-style: italic;">bona fide&#160;</font>offering thereof.</div>
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    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <table cellspacing="0" cellpadding="0" id="z33ad5b9c652349dbb16a01ca5ab44ebf" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;">

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          <td style="width: 4%; vertical-align: middle; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">&#160;</div>
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          <td style="width: 3%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">(3)</div>
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          <td style="width: 93%; vertical-align: middle; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: justify; line-height: 1.25;">To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering.</div>
          </td>
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    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <div style="text-align: justify; line-height: 1.25;">(b)&#160;&#160;&#160;&#160;The Registrant hereby undertakes that, for purposes of determining any liability under the Securities Act of 1933, each filing of the Registrant&#8217;s annual report pursuant to Section&#160;13(a) or
      15(d) of the Securities Exchange Act of 1934 (and, where applicable, each filing of an employee benefit plan&#8217;s annual report pursuant to Section&#160;15(d) of the Securities Exchange Act of 1934) that is incorporated by reference in the Registration
      Statement shall be deemed to be a new Registration Statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.</div>
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    <div style="text-align: justify; line-height: 1.25;">(c)&#160;&#160;&#160;&#160;Insofar as indemnification for liabilities arising under the Securities Act of 1933 may be permitted to directors, officers and controlling persons of the Registrant pursuant to the foregoing
      provisions, or otherwise, the Registrant has been advised that in the opinion of the SEC such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification
      against such liabilities (other than the payment by the Registrant of expenses incurred or paid by a director, officer or controlling person of the Registrant in the successful defense of any action, suit or proceeding) is asserted by such director,
      officer or controlling person in connection with the securities being registered, the Registrant will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the
      question whether such indemnification by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.</div>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" id="DSPFPageBreakArea">
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    <div style="text-align: center; line-height: 1.25; font-weight: bold;">SIGNATURES</div>
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    <div style="text-align: justify; text-indent: 28.35pt; line-height: 1.25;">Pursuant to the requirements of the Securities Act of 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements
      for filing on Form&#160;S-8&#160;and has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized, in Tel Aviv, Israel, on this 15th day of August, 2022.</div>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
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            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="vertical-align: middle;" colspan="2">
            <div style="line-height: 1.25; font-weight: bold;">CHEMOMAB THERAPEUTICS LTD.</div>
            <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;"><font style="line-height: 1.25;">&#160;</font></div>
          </td>
        </tr>
        <tr>
          <td style="width: 49.58%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 4%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">By:</div>
          </td>
          <td style="width: 46%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0); font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">/s/ Dale Pfost</div>
          </td>
        </tr>
        <tr>
          <td style="width: 49.58%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 4%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">Name:</div>
          </td>
          <td style="width: 46%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">Dale Pfost</div>
          </td>
        </tr>
        <tr>
          <td style="width: 49.58%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 4%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">Title:</div>
          </td>
          <td style="width: 46%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">Chief Executive Officer</div>
          </td>
        </tr>

    </table>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
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    <div style="text-align: center; line-height: 1.25; font-weight: bold;"><a name="POWER"><!--Anchor--></a>POWER OF ATTORNEY</div>
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    <div style="text-align: justify; text-indent: 28.35pt; line-height: 1.25;">KNOW ALL PERSONS BY THESE PRESENTS, that each individual whose signature appears below hereby constitutes and appoints Dale Pfost and Donald Marvin, jointly and severally, his
      or her true and lawful attorneys-in-fact and agents with full powers of substitution, for him and in his name, place and stead, in any and all capacities, to sign any and all supplements amendments (including post-effective amendments) to this
      Registration Statement, and to file the same, with all exhibits thereto, and all documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and
      authority to do and perform each and every act and thing requisite and necessary to be done in connection therewith, as fully to all intents and purposes as he might or could do in person, hereby ratifying and confirming all that said
      attorneys-in-fact and agents, or their substitute or substitutes, may lawfully do or cause to be done by virtue thereof.</div>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <div style="text-align: justify; text-indent: 28.35pt; line-height: 1.25;">Pursuant to the requirements of the Securities Act of 1933, this registration statement has been signed by the following persons in the capacities and on the dates indicated.</div>
    <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">&#160;</div>
    <table cellspacing="0" cellpadding="0" id="z995c90d83d1e4f42a36388bf4e6c3e35" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;">

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          <td style="width: 22.83%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25; font-weight: bold;">Signature</div>
          </td>
          <td style="width: 2.72%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: center; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 50.18%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: center; line-height: 1.25; font-weight: bold;">Title</div>
          </td>
          <td style="width: 2.72%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: center; line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 21.54%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: center; line-height: 1.25; font-weight: bold;">Date</div>
          </td>
        </tr>
        <tr>
          <td style="width: 22.83%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 2.72%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 50.18%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 2.72%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 21.54%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
        </tr>
        <tr>
          <td style="width: 22.83%; vertical-align: top; border-bottom: 2px solid black; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25; font-style: italic;">/s/ Dale Pfost</div>
          </td>
          <td style="width: 2.72%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 50.18%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">Chief Executive Officer, Chairman of the Board of Directors and Director (principal executive officer)</div>
          </td>
          <td style="width: 2.72%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">&#160;</td>
          <td style="width: 21.54%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="text-align: center; line-height: 1.25;">August 15, 2022</div>
          </td>
        </tr>
        <tr>
          <td style="width: 22.83%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">Dale Pfost</div>
          </td>
          <td style="width: 2.72%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
          <td style="width: 50.18%; vertical-align: top; font-family: 'Times New Roman',Times,serif;">
            <div style="line-height: 1.25;">&#160;</div>
          </td>
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        <div style="text-align: right; line-height: 1.25;"><u><font style="font-weight: bold;">Exhibit 5.1</font></u><br>
        </div>
        <div style="line-height: 1.25;"><br style="line-height: 1.25;">
        </div>
      </div>
      <div style="line-height: 1.25; text-align: center;"><img src="image00003.jpg"></div>
      <div style="line-height: 1.25">&#160;</div>
      <div style="line-height: 1.25;">
        <div style="text-align: right; line-height: 1.25;">August 15, 2022</div>
      </div>
      <table cellspacing="0" cellpadding="0" id="z25fbebf82c5e44e5b887b7f8cbfa9f61" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;">

          <tr>
            <td style="width: 100%; vertical-align: top;" colspan="3">
              <div style="line-height: 1.25;">
                <div style="line-height: 1.25;">Chemomab Therapeutics Ltd.</div>
                <div style="line-height: 1.25;">Kiryat Atidim, Building 7</div>
                <div style="line-height: 1.25;">Tel Aviv-Yafo, 6158002<br>
                  <u>Israel</u></div>
              </div>
            </td>
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        <div style="line-height: 1.25;"><br style="line-height: 1.25;">
        </div>
      </div>
      <div style="line-height: 1.25;">
        <div style="text-align: center; margin-left: 24.5pt; line-height: 1.25; font-weight: bold;">RE:&#160;<u>Registration
              on Form&#160;S-8</u></div>
      </div>
      <div style="line-height: 1.25;">
        <div style="line-height: 1.25;"><br style="line-height: 1.25;">
        </div>
        <div style="line-height: 1.25;">Ladies and Gentlemen:</div>
      </div>
      <div style="line-height: 1.25;">
        <div style="line-height: 1.25">&#160;</div>
        <div style="text-indent: 24.5pt; line-height: 1.25;">We have acted as Israeli counsel to Chemomab Therapeutics Ltd., an Israeli company (the &#8220;<font style="font-weight: bold;">Company</font>&#8221;), in connection with its filing of a registration statement on Form&#160;S-8&#160;on or about August 15, 2022 (the &#8220;<font style="font-weight: bold;">Registration Statement</font>&#8221;), under the Securities Act of 1933, as amended (the &#8220;<font style="font-weight: bold;">Securities Act</font>&#8221;),
          relating to the registration of 10,800,000 of the Company&#8217;s ordinary shares, no par value (&#8220;<font style="font-weight: bold;">Ordinary</font>&#160;<font style="font-weight: bold;">Shares</font>&#8221; and the &#8220;<font style="font-weight: bold;">Shares</font>&#8221;, respectively), resulting from an automatic annual increase as of January 1, 2022, including Shares that may be represented by American Depositary Shares (the &#8220;<font style="font-weight: bold;">ADSs</font>&#8221;), which may be issued under the Anchiano Therapeutics Ltd. 2017 Equity-Based Incentive Plan (the &#8220;<font style="font-weight: bold;">Plan</font>&#8221;).</div>
        <div style="line-height: 1.25">&#160;</div>
        <div style="text-indent: 24.5pt; line-height: 1.25;">ADSs that represent the Shares will be issued under the Deposit Agreement, dated February 14, 2019, by and among
          the Company, the Bank of New York Mellon, as depositary (the &#8220;<font style="font-weight: bold;">Depositary</font>&#8221;), and the owners and holders from time to time of ADSs issued
          thereunder (the &#8220;<font style="font-weight: bold;">Deposit Agreement</font>&#8221;).</div>
        <div style="line-height: 1.25">&#160;</div>
        <div style="text-indent: 24.5pt; line-height: 1.25;">In our capacity as counsel to the Company, we have examined originals or copies, certified or otherwise identified
          to our satisfaction, of the Company&#8217;s (i)&#160;Amended and Restated Articles of Association (the &#8220;<font style="font-weight: bold;">Articles</font>&#8221;), (ii) the Plan, (iii)&#160;resolutions of
          the Company&#8217;s board of directors and (iv)&#160;other statements of corporate officers and other representatives of the Company and other documents provided to us by the Company as we have deemed necessary or appropriate as a basis for this opinion. In
          such examination, we have assumed the genuineness of all signatures, the legal capacity of natural persons, the authenticity of all documents submitted to us as originals and the conformity with the original documents of all documents submitted
          to us as copies or facsimiles. As to any facts material to this opinion, to the extent that we did not independently establish relevant facts, we have relied on certificates of public officials and certificates of officers or other
          representatives of the Company. We have also assumed the truth of all facts communicated to us by the Company and that all consents, minutes and protocols of meetings of the Company&#8217;s board of directors, which have been provided to us, are true
          and accurate and prepared in accordance with the Company&#8217;s Articles and all applicable laws. In addition, we have assumed that the Company will receive the full consideration for the Ordinary Shares (which may consist, in part or in full, of
          services performed for the Company).</div>
        <div style="line-height: 1.25">&#160;</div>
        <div style="text-indent: 24.5pt; line-height: 1.25;">We are admitted to practice law in the State of Israel and the opinion expressed herein is expressly limited to
          the laws of the State of Israel.</div>
        <div style="line-height: 1.25">&#160;</div>
        <div style="text-indent: 24.5pt; line-height: 1.25;">On the basis of the foregoing, we are of the opinion that the Shares being registered pursuant to the Registration
          Statement (including Shares represented by ADSs), when issued and paid for in accordance with the Plan, pursuant to agreements with respect to the Plan and, as the case may be, pursuant to the terms of the awards that have been or may be granted
          under the Plan, will be validly issued, fully paid and&#160;non-assessable.</div>
        <div style="line-height: 1.25">&#160;</div>
        <div style="text-indent: 24.5pt; line-height: 1.25;">We hereby consent to the filing of this opinion as an exhibit to the Registration Statement. In giving this
          opinion and such consent, we do not admit that we are within the category of persons whose consent is required under Section&#160;7 of the Securities Act, the rules and regulations of the Securities and Exchange Commission promulgated thereunder or
          Item 509 of Regulation&#160;S-K&#160;promulgated under the Securities Act.</div>
        <div style="line-height: 1.25">&#160;</div>
        <div style="text-indent: 24.5pt; line-height: 1.25;">This opinion letter is rendered as of the date hereof and we disclaim any obligation to advise you of facts,
          circumstances, events or developments that may be brought to our attention after the effective date of the Registration Statement that may alter, affect or modify the opinions expressed herein.</div>
        <div style="text-indent: 24.5pt; line-height: 1.25;"> <br>
        </div>
      </div>
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            <td style="width: 25%; vertical-align: top;" colspan="1">&#160;</td>
            <td style="width: 20%; vertical-align: top;">
              <div style="text-indent: -12pt; margin-left: 12pt; line-height: 1.25;">Very truly yours,</div>
            </td>
            <td style="width: 55%; vertical-align: top;" colspan="1">&#160;</td>
          </tr>
          <tr>
            <td style="width: 25%; vertical-align: middle;" colspan="1">&#160;</td>
            <td style="width: 20%; vertical-align: middle;">&#160;</td>
            <td style="width: 55%; vertical-align: middle;" colspan="1">&#160;</td>
          </tr>
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            <td style="width: 25%; vertical-align: top; padding-bottom: 2px;" colspan="1">&#160;</td>
            <td style="width: 20%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25;">
                <div style="line-height: 1.25; font-style: italic;">/s/ Meitar | Law Offices</div>
              </div>
            </td>
            <td style="width: 55%; vertical-align: top; padding-bottom: 2px;" colspan="1">&#160;</td>
          </tr>

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      </div>
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</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>3
<FILENAME>exhibit_23-1.htm
<DESCRIPTION>EXHIBIT 23.1
<TEXT>
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    <div style="text-align: right;"><u><font style="font-weight: bold;">Exhibit 23.1</font></u> </div>
    <div> <br>
    </div>
    <div>
      <div style="text-align: center; line-height: 1.25; font-family: 'Times New Roman',Times,serif; font-weight: bold;">Consent of Independent Registered Public Accounting Firm</div>
    </div>
    <div> <br>
    </div>
    <div>
      <div style="line-height: 1.25;">The Board of Directors</div>
      <div style="line-height: 1.25;">Chemomab Therapeutics Ltd.:</div>
    </div>
    <div> <br>
    </div>
    <div>
      <div style="line-height: 1.25;">We consent to the use of our report dated March 30, 2022, with respect to the consolidated financial statements of Chemomab Therapeutics Ltd. incorporated herein by reference.</div>
    </div>
    <div>
      <div><br>
      </div>
      <div>
        <table cellspacing="0" cellpadding="0" border="0" id="z48d4ab4f4a2542a993e2be1890a9998e" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; color: #000000; width: 100%;">

            <tr>
              <td style="width: 100.00%;">/s/ Somekh Chaikin</td>
            </tr>

        </table>
      </div>
      <div>
        <div style="line-height: 1.25;">Somekh Chaikin</div>
      </div>
      <div>
        <div style="line-height: 1.25;">Member Firm of KPMG International</div>
        <div style="line-height: 1.25;">Tel Aviv, Israel</div>
        <div style="line-height: 1.25;"> <br>
        </div>
        <div style="line-height: 1.25;">August 15, 2022</div>
      </div>
      <div><br>
      </div>
      <hr align="center" style="border: none; border-bottom: 4px solid black; border-top: 1px solid black; height: 10px; color: #ffffff; background-color: #ffffff; text-align: center; margin-left: auto; margin-right: auto;"></div>
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<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>4
<FILENAME>exhibit_107-1.htm
<DESCRIPTION>EXHIBIT 107.1
<TEXT>
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    <title></title>
    <!-- Licensed to: Z-K Global
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    <hr align="center" style="border: none; border-bottom: 1px solid black; border-top: 4px solid black; height: 10px; color: #ffffff; background-color: #ffffff; text-align: center; margin-left: auto; margin-right: auto;">
    <div>
      <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">
        <div style="text-align: right; line-height: 1.25; font-weight: bold;"><u>Exhibit 107.1</u></div>
      </div>
      <div style="line-height: 1.25;">
        <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;"><br style="line-height: 1.25;">
        </div>
        <div style="text-align: center; line-height: 1.25; font-weight: bold;">CALCULATION OF FILING FEE TABLE</div>
      </div>
      <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">
        <div style="line-height: 1.25;"><br style="line-height: 1.25;">
        </div>
      </div>
      <div style="line-height: 1.25;">
        <div style="text-align: center; line-height: 1.25; font-weight: bold;">FORM S-8</div>
        <div style="text-align: center; line-height: 1.25;">(Form Type)</div>
      </div>
      <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">
        <div style="line-height: 1.25;"><br style="line-height: 1.25;">
        </div>
      </div>
      <div style="line-height: 1.25;">
        <div style="text-align: center; line-height: 1.25; font-weight: bold;">CHEMOMAB THERAPEUTICS LTD.</div>
        <div style="text-align: center; line-height: 1.25;">(Exact Name of Registrant as Specified in its Charter)</div>
      </div>
      <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">
        <div style="line-height: 1.25;"><br style="line-height: 1.25;">
        </div>
      </div>
      <div style="line-height: 1.25;">
        <div style="text-align: center; line-height: 1.25; font-weight: bold;"><u>Table 1: Newly Registered Securities</u></div>
        <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;"><br style="line-height: 1.25;">
        </div>
      </div>
      <table cellspacing="0" cellpadding="3" border="0" style="font-family: 'Times New Roman',Times,serif; font-size: 10pt; width: 100%; text-align: left; color: rgb(0, 0, 0);">

          <tr>
            <td style="width: 9.24%; vertical-align: bottom; text-align: center; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25; font-weight: bold;">Plan</div>
            </td>
            <td style="width: 8.86%; vertical-align: bottom; text-align: center; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25; font-weight: bold;">Security Type</div>
            </td>
            <td style="width: 8.98%; vertical-align: bottom; text-align: center; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25; font-weight: bold;">Security Class Title</div>
            </td>
            <td style="width: 11.94%; vertical-align: bottom; text-align: center; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25; font-weight: bold;">Fee Calculation Rule</div>
            </td>
            <td style="width: 11.07%; vertical-align: bottom; text-align: center; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25; font-weight: bold;">Amount Registered (1)</div>
            </td>
            <td style="width: 17.79%; vertical-align: bottom; text-align: center; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25; font-weight: bold;">Proposed Maximum Offering Price Per Unit (4)</div>
            </td>
            <td style="width: 11.73%; vertical-align: bottom; text-align: center; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25; font-weight: bold;">Maximum Aggregate Offering Price</div>
            </td>
            <td style="width: 7.39%; vertical-align: bottom; text-align: center; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25; font-weight: bold;">Fee Rate</div>
            </td>
            <td style="width: 13.01%; vertical-align: bottom; text-align: center; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0); border-right: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25; font-weight: bold;">Amount of Registration Fee</div>
            </td>
          </tr>
          <tr>
            <td style="width: 9.24%; vertical-align: top; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25;">2017 Equity-Based Incentive Plan (2)</div>
            </td>
            <td style="width: 8.86%; vertical-align: top; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25;">Equity</div>
            </td>
            <td style="width: 8.98%; vertical-align: top; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25;">Ordinary shares, no par value per share,</div>
            </td>
            <td style="width: 11.94%; vertical-align: top; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="text-align: center; line-height: 1.25;">Rule 457(c)<br>
                and 457(h)</div>
            </td>
            <td style="width: 11.07%; vertical-align: top; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="text-align: center; line-height: 1.25;">10,800,000 (3)</div>
            </td>
            <td style="width: 17.79%; vertical-align: top; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="text-align: center; line-height: 1.25;">$0.1785</div>
            </td>
            <td style="width: 11.73%; vertical-align: top; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="text-align: center; line-height: 1.25;">$1,927,800</div>
            </td>
            <td style="width: 7.39%; vertical-align: top; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="text-align: center; line-height: 1.25;">$92.70 per million dollars</div>
            </td>
            <td style="width: 13.01%; vertical-align: top; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0); border-right: 2px solid rgb(0, 0, 0);">
              <div style="text-align: center; line-height: 1.25;">$178.7</div>
            </td>
          </tr>
          <tr>
            <td style="width: 9.24%; vertical-align: top; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25;">&#160;</div>
            </td>
            <td colspan="4" style="width: 40.85%; vertical-align: bottom; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25; font-weight: bold;">Total Offering Amounts</div>
            </td>
            <td style="width: 17.79%; vertical-align: middle; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25;">&#160;</div>
            </td>
            <td style="width: 11.73%; vertical-align: top; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="text-align: center; line-height: 1.25;">$1,927,800</div>
            </td>
            <td style="width: 7.39%; vertical-align: middle; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25;">&#160;</div>
            </td>
            <td style="width: 13.01%; vertical-align: top; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0); border-right: 2px solid rgb(0, 0, 0);">
              <div style="text-align: center; line-height: 1.25;">$178.7</div>
            </td>
          </tr>
          <tr>
            <td style="width: 9.24%; vertical-align: top; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25;">&#160;</div>
            </td>
            <td colspan="4" style="width: 40.85%; vertical-align: bottom; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25; font-weight: bold;">Total Fee Offsets</div>
            </td>
            <td style="width: 17.79%; vertical-align: middle; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25;">&#160;</div>
            </td>
            <td style="width: 11.73%; vertical-align: middle; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25;">&#160;</div>
            </td>
            <td style="width: 7.39%; vertical-align: middle; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25;">&#160;</div>
            </td>
            <td style="width: 13.01%; vertical-align: middle; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0); border-right: 2px solid rgb(0, 0, 0);">
              <div style="text-align: center; line-height: 1.25;">$&#8212;</div>
            </td>
          </tr>
          <tr>
            <td style="width: 9.24%; vertical-align: top; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0); border-bottom: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25;">&#160;</div>
            </td>
            <td colspan="4" style="width: 40.85%; vertical-align: bottom; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0); border-bottom: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25; font-weight: bold;">Net Fee Due</div>
            </td>
            <td style="width: 17.79%; vertical-align: middle; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0); border-bottom: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25;">&#160;</div>
            </td>
            <td style="width: 11.73%; vertical-align: middle; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0); border-bottom: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25;">&#160;</div>
            </td>
            <td style="width: 7.39%; vertical-align: middle; border-top: 2px solid rgb(0, 0, 0); border-left: 2px solid rgb(0, 0, 0); border-bottom: 2px solid rgb(0, 0, 0);">
              <div style="line-height: 1.25;">&#160;</div>
            </td>
            <td style="width: 13.01%; vertical-align: top; border-width: 2px; border-style: solid; border-color: rgb(0, 0, 0);">
              <div style="text-align: center; line-height: 1.25;">$178.7</div>
            </td>
          </tr>

      </table>
      <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">
        <div style="line-height: 1.25;"><br style="line-height: 1.25;">
        </div>
      </div>
      <div style="line-height: 1.25;">
        <div style="text-align: justify; line-height: 1.25;">(1) Pursuant to Rule 416(a) under the Securities Act of 1933, as amended (the &#8220;Securities Act&#8221;), this Registration Statement also covers such indeterminate number of Ordinary Shares as may be
          offered or issued to prevent dilution resulting from stock splits, stock dividends, or similar transactions pursuant to the terms of the Anchiano Therapeutics Ltd. 2017 Equity-Based Incentive Plan (the &#8220;2017 Plan&#8221;).</div>
        <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;"><br style="line-height: 1.25;">
        </div>
        <div style="text-align: justify; line-height: 1.25;">(2) These shares may be represented by ADSs, each of which currently represents twenty (20) Ordinary Shares. ADSs issuable upon deposit of the Ordinary Shares registered hereby have been
          registered under a separate registration statement on Form F-6 (File No. 333-192259).</div>
        <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;"><br style="line-height: 1.25;">
        </div>
        <div style="text-align: justify; line-height: 1.25;">(3) Represents 10,800,000.00 additional ordinary shares, no par value (the &#8220;Ordinary Shares&#8221;) equal to 540,000 ADSs, authorized for issuance under the 2017 Plan, representing an automatic annual
          increase effective as of January 1, 2022 pursuant to the 2017 Plan.</div>
      </div>
      <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">
        <div style="line-height: 1.25;"><br style="line-height: 1.25;">
        </div>
      </div>
      <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;">
        <div style="text-align: justify; line-height: 1.25;">(4) Calculated in accordance with Rule 457(h)(1) and 457(c) promulgated under the Securities Act, based on the average of the low and high prices ($3.38 and $3.76) of the Registrant&#8217;s ADSs, as
          reported on the Nasdaq Capital Market on August 9, 2022, as adjusted to reflect the ratio of ADSs to Ordinary Shares as described in footnote (2) above.</div>
      </div>
      <div style="line-height: 1.25; font-family: 'Times New Roman',Times,serif;"><br style="line-height: 1.25;">
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end
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
