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CONSOLIDATED STATEMENTS OF CHANGES IN SHAREHOLDERS' EQUITY - USD ($)
$ in Thousands
Ordinary shares [Member]
Additional paid-in capital [Member]
Other Comprehensive Loss
Accumulated deficit [Member]
Total
Beginning balance at Dec. 31, 2015 $ 599 [1] $ 46,164 $ (34,115) $ 12,648
Beginning balance, shares at Dec. 31, 2015 [1] 984,292        
Issuance of ordinary shares and pre-funded warrants in August 2016 registered direct offering, net of issuance expenses in an amount of $615 [2] $ 32 5,227 5,259
Issuance of ordinary shares and pre-funded warrants in August 2016 registered direct offering, net of issuance expenses in an amount of $615, Shares [3] 53,635        
Exercise of warrants into ordinary shares $ 140 [1] (23) 117
Exercise of warrants into ordinary shares, shares [1] 229,153        
Share-based compensation [1] 1,209 1,209
Change in fair values of cash flow hedge        
Net loss [1] (8,826) (8,826)
Ending balance at Dec. 31, 2016 $ 771 [1] 52,577 (42,941) 10,407
Ending balance, shares at Dec. 31, 2016 [1] 1,267,080        
Issuance of ordinary shares and warrants in June 2017 registered direct offering, net of issuance expenses in an amount of $399 [4] $ 67 2,282 2,349
Issuance of ordinary shares and warrants in June 2017 registered direct offering, net of issuance expenses in an amount of $399 [4] 112,460        
Issuance of ordinary shares and warrants in November 2017 registered direct offering, net of issuance expenses in an amount of $378 [4] $ 114 2,066 2,180
Issuance of ordinary shares and warrants in November 2017 registered direct offering, net of issuance expenses in an amount of $378 [4] 189,387        
Exercise of warrants into ordinary shares $ 22 [1] (8) 14
Exercise of warrants into ordinary shares, shares [1] 35,474        
Share-based compensation 726 726
Share-based compensation, shares 1,033        
Change in fair values of cash flow hedge        
Net loss [1] (9,771) (9,771)
Ending balance at Dec. 31, 2017 $ 974 [1] 57,643 (52,712) 5,905
Ending balance, shares at Dec. 31, 2017 [1] 1,605,434        
Issuance of ordinary shares in May 2018 in the Public Offering, net of issuance expenses in an amount of $2,381 [5] $ 2,444 15,343 17,787
Issuance of ordinary shares in May 2018 in the Public Offering, net of issuance expenses in an amount of $2,381, shares [5] 3,669,129        
Exercise of warrants into ordinary shares $ 38 [1] (33) 5
Exercise of warrants into ordinary shares, shares [1] 56,121        
Share-based compensation [1] (65) (65)
Change in fair values of cash flow hedge [1] (13) (13)
Net loss [1] (10,589) (10,589)
Ending balance at Dec. 31, 2018 $ 3,456 [1] $ 72,888 $ (13) $ (63,301) $ 13,030
Ending balance, shares at Dec. 31, 2018 [1] 5,330,684        
[1] All shares amounts have been retroactively adjusted to reflect a 1-for-12 share reverse split, see Note 1C.
[2] Represents warrants issued to placement agent as part of issuance expenses
[3] Includes pre-funded warrants to purchase 209,524 ordinary shares at a purchase price of $22.20 per pre-funded warrant, issued in connection with the registered direct offering. See Note 9C(2)(h).
[4] Issuance expenses include certain warrants with a value of $49,229 and $58,298 issued in connection with the June 2017 and November 2017 registered direct offerings, respectively. See Note 9C(2)(j).
[5] Includes pre-funded warrants to purchase 450,909 ordinary shares at a purchase price of $5.49 per pre-funded warrant, issued in connection with the registered direct offering. See Note 9C(2)(k).