<SEC-DOCUMENT>0001181431-13-025187.txt : 20130503
<SEC-HEADER>0001181431-13-025187.hdr.sgml : 20130503
<ACCEPTANCE-DATETIME>20130503173048
ACCESSION NUMBER:		0001181431-13-025187
CONFORMED SUBMISSION TYPE:	3/A
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20130301
FILED AS OF DATE:		20130503
DATE AS OF CHANGE:		20130503

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			RXi Pharmaceuticals Corp
		CENTRAL INDEX KEY:			0001533040
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		1500 WEST PARK DRIVE
		STREET 2:		SUITE 210
		CITY:			WESTBOROUGH
		STATE:			MA
		ZIP:			01581
		BUSINESS PHONE:		(508) 767-3861

	MAIL ADDRESS:	
		STREET 1:		1500 WEST PARK DRIVE
		STREET 2:		SUITE 210
		CITY:			WESTBOROUGH
		STATE:			MA
		ZIP:			01581

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			CAUWENBERGH GEERT
		CENTRAL INDEX KEY:			0001285648

	FILING VALUES:
		FORM TYPE:		3/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-54910
		FILM NUMBER:		13813924

	MAIL ADDRESS:	
		STREET 1:		1 STULTS DRIVE
		CITY:			PLAINSBORO
		STATE:			NJ
		ZIP:			08536
</SEC-HEADER>
<DOCUMENT>
<TYPE>3/A
<SEQUENCE>1
<FILENAME>rrd378423.xml
<DESCRIPTION>FORM 3/A
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3/A</documentType>

    <periodOfReport>2013-03-01</periodOfReport>

    <dateOfOriginalSubmission>2013-03-01</dateOfOriginalSubmission>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001533040</issuerCik>
        <issuerName>RXi Pharmaceuticals Corp</issuerName>
        <issuerTradingSymbol>RXII</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001285648</rptOwnerCik>
            <rptOwnerName>CAUWENBERGH GEERT</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O RXI PHARMACEUTICALS CORPORATION</rptOwnerStreet1>
            <rptOwnerStreet2>1500 WEST PARK DRIVE, SUITE 210</rptOwnerStreet2>
            <rptOwnerCity>WESTBOROUGH</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>01581</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>President &amp; CEO</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.085</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2022-06-08</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>34155195</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The options will vest in a one-quarter installment of 8,538,799 shares on April 27, 2013 and 35 equal monthly installments thereafter of 711,567 shares beginning on May 27, 2013 with the last monthly installment of 711,551 shares on April 27, 2016.</footnote>
    </footnotes>

    <remarks>This amendment is filed to correct the vesting terms of the stock option award.</remarks>

    <ownerSignature>
        <signatureName>/s/ Caitlin Kontulis, attorney-in-fact</signatureName>
        <signatureDate>2013-05-03</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
