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Stock Option Plans and Warrants to Purchase Common Stock - Schedule of share-based compensation expense (Details) - USD ($) | 6 Months Ended | 12 Months Ended
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Jun. 30, 2025 | Jun. 30, 2024 | Dec. 31, 2024 | Dec. 31, 2023
Share-based compensation expense |  |  |  |
Share-Based Compensation | $ 163,112 | $ 117,636 | $ 329,815 | $ 370,182
Research and development |  |  |  |
Share-based compensation expense |  |  |  |
Share-Based Compensation |  |  | 131,917 | 150,466
General and administrative |  |  |  |
Share-based compensation expense |  |  |  |
Share-Based Compensation |  |  | $ 197,898 | $ 219,716

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- References No definition available. + Details
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- Definition Amount of noncash expense for share-based payment arrangement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 45 -Paragraph 28 -Subparagraph (a) -SubTopic 10 -Topic 230 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482740/230-10-45-28 + Details
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