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Consolidated Statements of Changes in Equity and Shareholders' Equity (Deficit) - USD ($) | Common Stock Public Offering | Common Stock Pre-funded warrants | Common Stock Existing Warrants | Common Stock New warrants | Common Stock | Additional Paid-In Capital Public Offering | Additional Paid-In Capital At Market Issuance Sales Agreement | Additional Paid-In Capital Pre-funded warrants | Additional Paid-In Capital Existing Warrants | Additional Paid-In Capital New warrants | Additional Paid-In Capital | Accumulated Other Comprehensive Income (Loss) | Accumulated Deficit | Public Offering | At Market Issuance Sales Agreement | Pre-funded warrants | Existing Warrants | New warrants | Total
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Balance at Dec. 31, 2023 |  |  |  |  | $ 649 |  |  |  |  |  | $ 228,203,706 | $ 22,243 | $ (225,704,176) |  |  |  |  |  | $ 2,522,422
Balance (in shares) at Dec. 31, 2023 |  |  |  |  | 648,761 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock pursuant to At Market Issuance Sales Agreement |  |  |  |  | $ 229 |  |  |  |  |  | 1,071,330 |  |  |  |  |  |  |  | 1,071,559
Issuance of common stock pursuant to At Market Issuance Sales Agreement (in shares) | 204,694 |  |  |  | 229,078 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Issuance costs |  |  |  |  |  | $ (625,065) | $ (24,484) |  |  |  |  |  |  | $ (625,065) | $ (24,484) |  |  |  |
Issuance of common stock and pre-funded warrants in connection with public offering |  |  |  |  | $ 205 |  |  |  |  |  | 4,741,195 |  |  |  |  |  |  |  | 4,741,400
Issuance of common stock and pre-funded warrants in connection with public offering (in shares) |  |  |  |  | 204,694 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock to vendors |  |  |  |  | $ 5 |  |  |  |  |  | 15,795 |  |  |  |  |  |  |  | $ 15,800
Issuance of common stock to vendors (in shares) |  |  |  |  | 5,000 |  |  |  |  |  |  |  |  |  |  |  |  |  | 5,000
Fractional shares issued in June 2024 reverse stock split |  |  |  |  | $ 115 |  |  |  |  |  | (115) |  |  |  |  |  |  |  |
Fractional shares issued in June 2024 reverse stock split (in shares) |  |  |  |  | 114,735 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock upon exercise of warrants |  | $ 537 | $ 703 | $ 35 |  |  |  | $ 8,063 | $ 4,218,047 | $ 222,787 |  |  |  |  |  | $ 8,600 | $ 4,218,750 | $ 222,822 |
Issuance of common stock upon exercise of warrant |  | 537,500 | 703,125 | 34,816 |  |  |  |  |  |  |  |  |  |  |  |  |  | 34,816 |
Issuance costs associated with warrant inducement |  |  |  |  |  |  |  |  |  |  | (7,552,457) |  |  |  |  |  |  |  | $ (7,552,457)
Warrant modification - incremental fair value |  |  |  |  |  |  |  |  |  |  | 7,177,683 |  |  |  |  |  |  |  | 7,177,683
Issuance of common stock from conversion of debt |  |  |  |  | $ 36 |  |  |  |  |  | 254,220 |  |  |  |  |  |  |  | 254,256
Issuance of common stock from conversion of debt (in shares) |  |  |  |  | 36,790 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Share-based compensation expense |  |  |  |  |  |  |  |  |  |  | 329,815 |  |  |  |  |  |  |  | 329,815
Foreign currency translation adjustment |  |  |  |  |  |  |  |  |  |  |  | 23,546 |  |  |  |  |  |  | 23,546
Net loss |  |  |  |  |  |  |  |  |  |  |  |  | (8,266,576) |  |  |  |  |  | (8,266,576)
Balance at Dec. 31, 2024 |  |  |  |  | $ 2,514 |  |  |  |  |  | 238,040,520 | 45,789 | (233,970,752) |  |  |  |  |  | $ 4,118,071
Balance (in shares) at Dec. 31, 2024 |  |  |  |  | 2,514,499 |  |  |  |  |  |  |  |  |  |  |  |  |  | 2,514,499
Issuance of common stock pursuant to At Market Issuance Sales Agreement |  |  |  |  | $ 1,760 |  |  |  |  |  | 4,664,661 |  |  |  |  |  |  |  | $ 4,666,421
Issuance of common stock pursuant to At Market Issuance Sales Agreement (in shares) |  |  |  |  | 1,758,725 |  |  |  |  |  |  |  |  | 4,064,080 |  |  |  |  |
Issuance costs |  |  |  |  |  | $ (776,086) | $ (103,847) |  |  |  |  |  |  | $ (776,086) | $ (103,847) |  |  |  |
Issuance of common stock and pre-funded warrants in connection with public offering |  |  |  |  | $ 4,064 |  |  |  |  |  | 7,494,458 |  |  |  |  |  |  |  | 7,498,522
Issuance of common stock and pre-funded warrants in connection with public offering (in shares) |  |  |  |  | 4,064,080 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock to vendors |  |  |  |  | $ 32 |  |  |  |  |  | 76,568 |  |  |  |  |  |  |  | $ 76,600
Issuance of common stock to vendors (in shares) |  |  |  |  | 32,346 |  |  |  |  |  |  |  |  |  |  |  |  |  | 32,346
Issuance of common stock upon exercise of warrants |  | $ 1,491 |  | $ 225 |  |  |  |  |  | $ 303,525 |  |  |  |  |  | $ 1,491 |  | $ 303,750 |
Issuance of common stock upon exercise of warrant |  | 1,491,480 |  | 225,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 225,000
Share-based compensation expense |  |  |  |  |  |  |  |  |  |  | 587,583 |  |  |  |  |  |  |  | $ 587,583
Net loss |  |  |  |  |  |  |  |  |  |  |  |  | (11,080,380) |  |  |  |  |  | (11,080,380)
Balance at Dec. 31, 2025 |  |  |  |  | $ 10,086 |  |  |  |  |  | $ 250,287,382 | $ 45,789 | $ (245,051,132) |  |  |  |  |  | $ 5,292,125
Balance (in shares) at Dec. 31, 2025 |  |  |  |  | 10,086,130 |  |  |  |  |  |  |  |  |  |  |  |  |  | 10,086,130

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