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Stock-Based Compensation - Schedule of Stock Option Awards and Restricted Stock Grants (Details)
9 Months Ended
Sep. 30, 2018
USD ($)
$ / shares
shares
Weighted average contractual terms of equity awards (in years), equity awards, outstanding, ending balance 9 years 4 months 24 days
Weighted average contractual terms of equity awards (in years), equity awards exercisable, ending balance 9 years 3 months 19 days
Stock Options [Member]  
Equity awards, outstanding, beginning balance | shares 703,442
Equity awards granted | shares 2,629,004
Vested and issued | shares
Equity awards forfeited, cancelled or expired | shares (113,701)
Equity awards, outstanding, ending balance | shares 3,218,745
Aggregate intrinsic value of outstanding awards, ending balance | $ $ 1,384,245
Equity awards exercisable, ending balance | shares 1,677,998
Aggregate intrinsic value of awards exercisable, ending balance | $ $ 706,552
Weighted average exercise price, equity awards, outstanding, beginning balance | $ / shares $ 10.34
Weighted average exercise price, equity awards granted | $ / shares 2.26
Weighted average exercise price, vested and issued | $ / shares
Weighted average exercise price, equity awards forfeited, cancelled or expired | $ / shares 40.23
Weighted average exercise price, equity awards, outstanding, ending balance | $ / shares 2.67
Weighted average exercise price, equity awards exercisable, ending balance | $ / shares $ 2.94
Restricted Stock Awards [Member]  
Non-vested restricted stock outstanding, equity awards, outstanding, beginning balance | shares
Non-vested restricted stock outstanding, equity awards granted | shares 35,000
Non-vested restricted stock outstanding, vested and issued | shares (6,000)
Non-vested restricted stock outstanding, equity awards forfeited, cancelled or expired | shares
Non-vested restricted stock outstanding, equity awards, outstanding, ending balance | shares 29,000
Non-vested restricted stock outstanding, aggregate intrinsic value of outstanding awards, ending balance | $ $ 1,700
Weighted average grant date fair value, equity awards, outstanding, beginning balance | $ / shares
Weighted average grant date fair value, equity awards granted | $ / shares 2.71
Weighted average grant date fair value, vested and issued | $ / shares 2.64
Weighted average grant date fair value, equity awards forfeited, cancelled or expired | $ / shares
Weighted average grant date fair value, equity awards, outstanding, ending balance | $ / shares $ 2.72