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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Cash flows from operating activities:    
Net loss $ (17,363,937) $ (15,721,334)
Non-cash items included in net loss:    
Depreciation and amortization 261,513 511,587
Change in fair value of earn-out milestone liability (3,567,671) (670,172)
Impairment of in-process research and development 4,510,000 2,520,000
Recognition of deferred revenue (375,000) (375,000)
Stock-based compensation costs 3,985,829 951,488
Restricted shares issued 29,841
Amortization of deferred finance charges and debt discount associated with notes payable 101,695 35,370
Change in deferred rent liability (6,009) 61,328
Net changes in:    
Accrued interest on investment securities (22,306) 4,008
Advances, deposits and other current assets (231,991) 115,106
Accounts payable and accrued liabilities (399,935) 134,440
Net cash (used in) operating activities: (13,077,971) (12,433,179)
Cash flows from investing activities:    
Purchases of investment securities (15,574,587)
Proceeds from sale and maturity of investment securities 9,750,000 1,680,000
(Deposit) refund on corporate office lease (50,000) 100,000
Purchases of property and equipment (81,778) (21,126)
Net cash (used in) provided by investing activities (5,956,365) 1,758,874
Cash flows from financing activities:    
Proceeds from sale of common stock equity, net of issuance costs 1,236,584 8,405,190
Proceeds from notes payable, net of issuance costs 9,725,000
Proceeds from exercise of common stock warrants 4,925,886
Principal payments on notes payable (2,595,923)
Net cash provided by financing activities 10,961,584 10,735,153
(Decrease) increase in cash and cash equivalents (8,072,752) 60,848
Cash and cash equivalents at beginning of period 11,444,055 2,624,162
Cash and cash equivalents at end of period 3,371,303 2,685,010
Supplemental disclosures of cash flow information:    
Interest paid 259,064 56,386
Non-cash financing activities:    
Fair value of common stock issued as equity issuance costs and charged against paid in capital 450,000
Fair value of warrants issued in connection with notes payable 507,116
Total non-cash financing activites $ 957,116