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Acquisition of EGEN, Inc. (Details Narrative) - USD ($) |  | 1 Months Ended | 3 Months Ended | 12 Months Ended
--- | --- | --- | --- | ---
Jun. 20, 2014 | Dec. 31, 2016 | Jun. 20, 2014 | Sep. 30, 2018 | Dec. 31, 2017 | Sep. 30, 2017 | Dec. 31, 2016 | Dec. 31, 2018 | Dec. 31, 2017 | Dec. 31, 2016
Asset impairment charges, total |  |  |  | $ 2,400,000 |  | $ 2,500,000 |  |  |  |
Business Combination, Consideration Transferred, Liabilities Incurred |  |  |  | 4,500,000 |  |  |  |  |  |
Finite-lived intangible assets, net, ending balance |  | $ 1,022,924 |  |  | $ 795,608 |  | $ 1,022,924 | 568,292 | 795,608 | $ 1,022,924
Gain (Loss) from Change in Fair Value of Earn out Milestone Liability |  |  |  |  |  |  |  | (3,630,861) | (649,701) |
Assets |  |  |  |  | 47,514,433 |  |  | 46,855,587 | 47,514,433 |
Purchase Agreement [Member] |  |  |  |  |  |  |  |  |  |
Finite-lived intangible assets, net, ending balance |  |  |  |  | 795,608 |  |  | 568,292 | 795,608 |
Finite-lived intangible assets, accumulated amortization |  |  |  |  | 795,606 |  |  | 1,022,922 | 795,606 |
IPR&D Drug Technology Platforms [Member] |  |  |  |  |  |  |  |  |  |
Asset impairment charges, total |  | $ 1,400,000 |  |  |  |  | $ 1,400,000 |  |  |
EGEN Inc [Member] |  |  |  |  |  |  |  |  |  |
Potential future earn-out payments | $ 30,400,000 |  | $ 30,400,000 |  |  |  |  |  |  |
Payments to Acquire Businesses, Gross |  |  | $ 3,000,000 |  |  |  |  |  |  |
Stock issued during period, shares, acquisitions |  |  | 241,590 |  |  |  |  |  |  |
Business Combination, Consideration Transferred, Liabilities Incurred | 13,900,000 |  |  |  |  |  |  | 8,900,000 | 12,500,000 | $ 13,200,000
Gain (Loss) from Change in Fair Value of Earn out Milestone Liability |  |  |  |  |  | 3,900,000 |  | 3,600,000 | 600,000 |
Goodwill, acquisition |  |  |  |  |  |  |  | 2,000,000 |  |
EGEN Inc [Member] | Purchase Agreement [Member] |  |  |  |  |  |  |  |  |  |
Finite-lived intangible assets acquired |  |  |  |  |  |  |  | $ 1,600,000 |  |
Finite-lived intangible asset, useful life |  |  |  |  |  |  |  | 7 years |  |
Amortization expense |  |  |  |  |  |  |  | $ 227,316 | 227,316 |
EGEN Inc [Member] | IPR&D Drug Technology Platforms [Member] |  |  |  |  |  |  |  |  |  |
Indefinite lived intangible assets |  |  |  |  |  |  |  | 24,200,000 |  |
EGEN Inc [Member] | Glioblastoma Multiforme Brain Cancer [Member] |  |  |  |  |  |  |  |  |  |
Asset impairment charges, total |  |  |  | $ 6,900,000 | 6,900,000 | $ 9,400,000 |  | 4,510,000 | 2,520,000 |
IPR&D costs |  |  |  |  |  |  |  | 15,736,491 | 20,246,491 |
EGEN Inc [Member] | Ovarian Cancer [Member] |  |  |  |  |  |  |  |  |  |
Finite-lived intangible assets, net, ending balance |  |  |  |  | $ 13,300,000 |  |  | 13,300,000 | $ 13,300,000 |
Initial assets value |  |  |  |  |  |  |  | 6,900,000 |  |
Assets |  |  |  |  |  |  |  | $ 2,400,000 |  |
EGEN Inc [Member] | Maximum [Member] |  |  |  |  |  |  |  |  |  |
Total purchase price for the asset acquisition |  |  | $ 44,400,000 |  |  |  |  |  |  |
Potential future earn-out payments | $ 30,400,000 |  | $ 30,400,000 |  |  |  |  |  |  |

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