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Stock-Based Compensation (Tables) | 12 Months Ended
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Dec. 31, 2018
Disclosure of Compensation Related Costs, Share-based Payments [Abstract] |
Summary of Stock Option Awards | A summary of stock option awards as of December 31, 2018 and changes during the two-year period ended December 31, 2018 is presented below:
Stock Options |  | Number Outstanding |  |  | Weighted Average Exercise Price |  |  | Weighted Average Remaining Contractual Term (years) |  |  | Aggregate Intrinsic Value |
Outstanding at January 1, 2017 |  |  | 211,213 |  |  | $ | 61.59 |  |  |  |  |  |  |  |  |
Granted |  |  | 535,964 |  |  | $ | 2.69 |  |  |  |  |  |  |  |  |
Canceled or expired |  |  | (43,735 | ) |  | $ | 164.12 |  |  |  |  |  |  |  |  |
Outstanding at December 31, 2017 |  |  | 703,442 |  |  | $ | 10.34 |  |  |  |  |  |  |  |  |
Granted |  |  | 2,629,004 |  |  | $ | 2.26 |  |  |  |  |  |  |  |  |
Canceled or expired |  |  | (183,703 | ) |  | $ | 25.96 |  |  |  |  |  |  |  |  |
Outstanding at December 31, 2018 |  |  | 3,148,743 |  |  | $ | 2.67 |  |  |  | 9.2 |  |  | $ | - |
Exercisable at December 31, 2018 |  |  | 1,689,902 |  |  | $ | 2.97 |  |  |  | 9.1 |  |  | $ | - |
Summary of Non-vested Restricted Stock Awards | A summary of the status of the Company’s non-vested restricted stock awards as of December 31, 2018 and changes during the two year period ended December 31, 2018, is presented below:
Restricted Stock |  | Number Outstanding |  |  | Weighted Average Grant Date Fair Value |
Non-vested stock awards outstanding at January 1, 2017 |  |  | 4,785 |  |  | $ | 37.42 |
Granted |  |  | (3,357 | ) |  | $ | 42.20 |
Vested and issued |  |  | (1,428 | ) |  | $ | 26.18 |
Non-vested stock awards outstanding at December 31, 2017 |  |  | - |  |  | $ | - |
Granted |  |  | 35,000 |  |  | $ | 2.71 |
Vested and issued |  |  | (6,000 | ) |  | $ | 2.77 |
Forfeited |  |  | (6,500 | ) |  | $ | 2.64 |
Non-vested stock awards outstanding at December 31, 2018 |  |  | 22,500 |  |  | $ | 2.72 |
Summary of Stock Options Outstanding | A summary of stock options outstanding at December 31, 2018 by price range is as follows:
|  | Options Outstanding |  |  | Options Exercisable |
Range of Exercise Prices |  |  | Number |  |  |  | Weighted Average Remaining Contractual Term (in years) |  |  |  | Weighted Average Exercise Price |  |  |  | Number |  |  |  | Weighted Average Remaining Contractual Term (in years) |  |  |  | Weighted Average Exercise Price |
Up to $5.00 |  |  | 3,084,252 |  |  |  | 9.2 |  |  | $ | 2.34 |  |  |  | 1,625,807 |  |  |  | 9.2 |  |  | $ | 2.34 |
Above $5.00 to $81.90 |  |  | 64,491 |  |  |  | 7.0 |  |  | $ | 19.00 |  |  |  | 64,095 |  |  |  | 7.0 |  |  | $ | 19.00 |
|  |  | 3,148,743 |  |  |  |  |  |  |  |  |  |  |  | 1,689,902 |  |  |  |  |  |  |  |  |
Schedule of Assumptions Used to Determine Fair Value of Options Granted | The model is also sensitive to changes in assumptions, which can materially affect the fair value estimate. The Company used the following assumptions for determining the fair value of options granted under the Black-Scholes option pricing model:
|  | Year Ended December 31, |
|  | 2018 |  |  | 2017 |
Risk-free interest rate |  |  | 2.82 to 3.02 | % |  |  | 2.21 to 2.32 | %
Expected volatility |  |  | 99.9 - 102.12 | % |  |  | 90.4 - 100.8 | %
Expected life (in years) |  |  | 8.5 to 10 |  |  |  | 10 |
Expected dividend yield |  |  | 0.0 | % |  |  | 0.0 | %

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- Definition Tabular disclosure of option exercise prices, by grouped ranges, including the upper and lower limits of the price range, the number of shares under option, weighted average exercise price and remaining contractual option terms. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 + Details
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- Definition Disclosure of the number and weighted-average grant date fair value for restricted stock and restricted stock units that were outstanding at the beginning and end of the year, and the number of restricted stock and restricted stock units that were granted, vested, or forfeited during the year. + References No definition available. + Details
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