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Stockholders' Equity (Details Narrative) - USD ($)
1 Months Ended 3 Months Ended 12 Months Ended 68 Months Ended
Dec. 04, 2018
Oct. 27, 2018
Oct. 26, 2018
Aug. 31, 2018
Oct. 27, 2017
Oct. 27, 2017
Oct. 04, 2017
Jul. 06, 2017
Jun. 09, 2017
May 26, 2017
May 16, 2017
Feb. 14, 2017
May 27, 2015
Feb. 01, 2013
Sep. 30, 2018
Dec. 31, 2017
Dec. 31, 2018
Dec. 31, 2017
Sep. 30, 2018
Jun. 26, 2017
Jun. 30, 2016
Jan. 15, 2014
Feb. 22, 2013
Shelf registration statement amount                             $ 75,000,000                
Common stock, shares authorized                               112,500,000 112,500,000 112,500,000     75,000,000    
Preferred stock, shares authorized                               100,000 100,000 100,000          
Aggregate of common and preferred stock, shares authorized                                 112,600,000            
Reverse stock split                   14-for-1 reverse stock split                          
Stock issued during period split stock                   14 56,982,418                        
Stock issued during period reverse stock split                   14 4,070,172                        
Class of warrant or right, outstanding                     2,400,000           1,600,000            
Share-based compensation arrangement by share-based payment award, options, outstanding, number, ending balance                     200,000           3,148,743            
Common stock, par or stated value per share                               $ 0.01 $ 0.01 $ 0.01          
Class of warrant or right, number of securities called by warrants or rights                               9,231,628 190,114 9,231,628   506,627      
Class of warrant or right, exercise price of warrants or rights                                 $ 5.75     $ 1.65      
Proceeds from warrant exercises                                 $ 21,140,304          
Fair value of common stock issued as equity issuance costs and charged against paid in capital                                 450,000          
Series AA Warrant [Member]                                              
Stock issued during period, shares, exercise of warrants                                   747,254          
Proceeds from warrant exercises                                   $ 2,400,000          
Pre-Funded Series BB Warrant [Member]                                              
Stock issued during period, shares, exercise of warrants                                   185,713          
2013 Warrants, 2014 Warrants, and June 2016 Warrants [Member]                                              
Proceeds from warrant exercises                 $ 2,100,000                            
Increase (decrease) in fair value of warrants                 $ 200,000                            
2015 Warrants [Member]                                              
Proceeds from warrant exercises                         $ 800,000                    
Increase (decrease) in fair value of warrants                         100,000                    
June 2016 Warrants [Member]                                              
Proceeds from warrant exercises                         $ 800,000                    
July 2017 Direct Offering [Member]                                              
Stock issued during period, shares, new issues               2,050,000                              
Class of warrant or right, number of securities called by each warrant or right             4,665,000                                
Share price               $ 2.07                              
Proceeds from issuance of common stock, gross               $ 4,243,500                              
Proceeds from issuance of warrants             $ 16,600,000                                
July 2017 Direct Offering [Member] | Pre-Funded Series CCC Warrants [Member]                                              
Class of warrant or right, number of securities called by warrants or rights               385,000                              
Class of warrant or right, offered price of warrants or rights               $ 2.06                              
Beneficial ownership percentage threshold               9.99%                              
Proceeds from issuance of warrants               $ 793,100                              
Class of warrant or right, exercise price of warrants or rights               $ 0.01                              
Class of warrant or right, exercised during period                               385,000              
July 2017 Direct Offering [Member] | Series AAA Warrants [Member]                                              
Class of warrant or right, number of securities called by warrants or rights               2,435,000                              
Class of warrant or right, exercise price of warrants or rights             $ 2.07 $ 2.07                              
July 2017 Direct Offering [Member] | Series BBB Warrants [Member]                                              
Class of warrant or right, number of securities called by warrants or rights               2,435,000                              
Class of warrant or right, exercise price of warrants or rights             $ 4.75 $ 4.75                              
July 2017 Direct Offering [Member] | Series DDD Warrants [Member]                                              
Class of warrant or right, number of securities called by warrants or rights             1,166,250                                
Class of warrant or right, number of securities called by each warrant or right             1                                
Warrants issued, expiration period             1 year                                
Class of warrant or right, exercise price of warrants or rights             $ 6.20                                
February 14, 2017 Public Offering [Member]                                              
Stock issued during period, shares, new issues                       1,384,704                      
Shares issued, price per share                       $ 3.22                      
Maximum beneficial ownership of the purchaser                       9.99%                      
Proceeds from issuance of common stock                       $ 5,000,000                      
February 14, 2017 Public Offering [Member] | Series AA Warrant [Member]                                              
Class of warrant or right, number of securities called by warrants or rights                       1,177,790                      
Number of warrant to surrender     321,428                                        
Number of exchange surrender received common stock     160,414                                        
Broker and legal fees     $ 100,000                                        
Class of warrant or right, exercise price of warrants or rights                       $ 3.22                      
Class of warrant or right, term                       5 years                      
February 14, 2017 Public Offering [Member] | Pre-Funded Series BB Warrant [Member]                                              
Class of warrant or right, number of securities called by warrants or rights                       185,713                      
Class of warrant or right, exercise price of warrants or rights                       $ 0.14                      
Shares issued, price per share                       $ 3.08                      
May 2015 Common Stock Offering [Member] | 2015 Warrants [Member]                                              
Class of warrant or right, number of securities called by warrants or rights                         139,284                    
Class of warrant or right, exercise price of warrants or rights                         $ 36.40                    
Aspire Purchase Agreement [Member]                                              
Fair value of common stock issued as equity issuance costs and charged against paid in capital                             $ 450,000                
ATM Agreement [Member]                                              
Stock issued during period, shares, new issues                                     1,784,396        
Proceeds from issuance of common stock                                     $ 12,800,000        
Aggregate offering price                           $ 25,000,000                  
Proceeds from sale equity                                 $ 1,200,000 $ 3,900,000          
Sale of common stock, shares                                 457,070 1,221,348          
Investor [Member]                                              
Class of warrant or right, outstanding                               7,617,148   7,617,148          
Class of warrant or right, number of securities called by warrants or rights                                 1,600,000            
Proceeds from issuance of warrants                                   $ 22,000,000          
Underwriting Agreement [Member] | Oppenheimer & Co. Inc. [Member]                                              
Stock issued during period, shares, new issues           2,640,000                                  
Common stock, par or stated value per share         $ 0.01 $ 0.01                                  
Class of warrant or right, number of securities called by warrants or rights         1,320,000 1,320,000                                  
Warrant, description           Each share of Common Stock is being sold together with 0.5 warrants (the "Investor Warrants"), each whole Investor Warrant being exercisable for one share of Common Stock, at an offering price of $2.50 per share and related Investor Warrants.                                  
Warrant Exchange Agreements [Member]                                              
Stock issued during period, shares, new issues                                 820,714            
Warrant Exchange Agreements [Member] | February 14, 2017 Public Offering [Member]                                              
Number of exchange surrender received common stock     321,428                                        
Broker and legal fees     $ 130,000                                        
Warrant Exchange Agreements [Member] | Investor [Member]                                              
Number of warrant to surrender     1,320,000                                        
Number of exchange surrender received common stock     820,714                                        
Exercise Agreements [Member] | 2013 Warrants, 2014 Warrants, and June 2016 Warrants [Member]                                              
Class of warrant or right, number of securities called by warrants or rights                                             790,410
Class of warrant or right, exercise price of warrants or rights                                             $ 2.70
Aspire Purchase Agreement [Member]                                              
Stock issued during period, shares, new issues       164,835                                      
Aggregate offering price, additions       $ 15,000,000                                      
Aggregate offering price, term       24 months                                      
Aggregate offering price       $ 15,000,000                                      
Maximum number of shares purchased per day       100,000                                      
Aggregate offering price, description       The lowest sale price of the Company's common stock on the purchase date; or the arithmetic average of the three (3) lowest closing sale prices for the Company's common stock during the ten (10) consecutive trading days ending on the trading day immediately preceding the purchase date.                                      
Maximum number of shares purchased per day, additional       2,000,000                                      
Aspire purchase agreement, terms       In addition, on any date on which the Company submits a Purchase Notice to Aspire Capital in an amount equal to at least 100,000 shares, the Company also has the right, in its sole discretion, to present Aspire Capital with a volume-weighted average price purchase notice (each, a "VWAP Purchase Notice") directing Aspire Capital to purchase an amount of stock equal to up to 30% of the aggregate shares of the Company's common stock traded on its principal market on the next trading day (the "VWAP Purchase Date"), subject to a maximum number of shares the Company may determine. The purchase price per share pursuant to such VWAP Purchase Notice is generally 97% of the volume-weighted average price for the Company's common stock traded on its principal market on the VWAP Purchase Date.                                      
Purchase Agreement [Member]                                              
Stock issued during period, shares, new issues                                 100,000            
Proceeds from issuance of common stock                                 $ 200,000            
Purchase Agreement [Member] | March 28, 2019 [Member]                                              
Stock issued during period, shares, new issues                                 600,000            
Proceeds from issuance of common stock                                 $ 1,300,000            
Capital on DemandTM Sales Agreement [Member]                                              
Aggregate offering price $ 16,000,000                                            
Aggregate offering price, description (i) the sale of all shares of our common stock subject to the Sales Agreement, and (ii) the termination of the Capital on Demand Agreement by JonesTrading or Celsion. The Capital on Demand Agreement may be terminated by JonesTrading or the Company at any time upon 10 days' notice to the other party, or by JonesTrading at any time in certain circumstances, including the occurrence of a material adverse change in the Company.                                            
Commission percentage for gross proceeds from common stock 3.00%                                            
Capital on Demand Agreement [Member] | March 28, 2019 [Member]                                              
Stock issued during period, shares, new issues                                 122,186            
Proceeds from issuance of common stock                                 $ 300,000            
Warrant [Member]                                              
Class of warrant or right, outstanding                     33,500,000           1,200,000            
Share-based compensation arrangement by share-based payment award, options, outstanding, number, ending balance                     2,400,000                        
Class of warrant or right, number of securities called by each warrant or right         2.325 2.325                                  
Class of warrant or right, offered price of warrants or rights         $ 3.00 $ 3.00                                  
Warrants issued, expiration period   5 years                                          
Warrant [Member] | Maximum [Member]                                              
Class of warrant or right, number of securities called by warrants or rights                 790,410                         64,348 95,811
Class of warrant or right, exercise price of warrants or rights                 $ 2.70                         $ 57.40 $ 74.34
Investor Warrants [Member] | October 2017 Underwritten Offering [Member]                                              
Class of warrant or right, number of securities called by warrants or rights         66,000 66,000                                  
Class of warrant or right, number of securities called by each warrant or right         2.87 2.87                                  
Warrants issued, expiration period         5 years                                    
Proceeds from issuance of common stock and warrants         $ 6,600,000                                    
Investor Warrants [Member] | Underwriting Agreement [Member] | Oppenheimer & Co. Inc. [Member]                                              
Class of warrant or right, number of securities called by each warrant or right         2.50 2.50