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Warrants - Summary of Warrant Activity (Details) - Warrant [Member] - USD ($)
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Number of Warrants Issued, Warrants outstanding, Beginning Balance 3,058,402 1,487,958
Number of Warrants Issued, Warrants issued 190,114 9,231,628
Number of Warrants Issued, Warrants exercised   (7,617,147)
Number of Warrants Issued, Warrants cancelled in exchange for common stock (1,641,427)  
Number of Warrants Issued, Warrants expired (13,927) (44,037)
Number of Warrants Issued, Warrants outstanding and exercisable, Ending Balance 1,593,162 3,058,402
Weighted Average Exercise Price, Warrants outstanding, Beginning Balance $ 5.29 $ 9.39
Weighted Average Exercise Price, Warrants issued 2.63 3.46
Weighted Average Exercise Price, Warrants exercised   2.89
Weighted Average Exercise Price, Warrants cancelled in exchange for common stock 3.04  
Weighted Average Exercise Price, Warrants expired 226.24 209.23
Weighted Average Exercise Price, Warrants outstanding and exercisable, Ending Balance $ 5.36 $ 5.29
Aggregate intrinsic value of outstanding warrants  
Weighted average remaining contractual terms (years) 1 year 10 months 14 days