Financial Condition and Business Plan (Details Narrative) - USD ($)	3 Months Ended	12 Months Ended
Mar. 31, 2019	Dec. 31, 2018
Cumulated net losses	$ (276,032,699)	$ (273,665,247)
Cash, investment securities and interest receivable	23,800,000
Common Stock Sales Agreement [Member] \| Aspire Capital Fund, LLC [Member]
Proceeds from available future sale of equity under common stock purchase agreement	28,600,000
New Jersey [Member]
Tax benefits of EDA		11,100,000
Net cash proceeds for net operating loss		$ 10,400,000
New Jersey [Member] \| June 2019 [Member]
Unrecognized tax benefits	3,900,000
New Jersey [Member] \| Maximum [Member]
Tax benefits of EDA	$ (12,500,000)

The cumulative amount of the reporting entity's undistributed earnings or deficit.

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02(30)(a)(3))
-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 944
-SubTopic 210
-Section S99
-Paragraph 1
-Subparagraph (SX 210.7-03(a)(23)(a)(4))
-URI http://asc.fasb.org/extlink&oid=119400593&loc=d3e572229-122910

Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 505
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.3-04)
-URI http://asc.fasb.org/extlink&oid=27012166&loc=d3e187085-122770

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