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Stockholders' Equity (Details Narrative) - USD ($)
 1 Months Ended 3 Months Ended 12 Months Ended 74 Months Ended
Dec. 04, 2018
Aug. 31, 2018
May 26, 2017
May 16, 2017
Feb. 01, 2013
Sep. 30, 2018
Mar. 31, 2019
Dec. 31, 2018
Mar. 31, 2019
Jun. 30, 2016
Shelf registration statement amount           $ 75,000,000        
Common stock, shares authorized             112,500,000 112,500,000 112,500,000 75,000,000
Preferred stock, shares authorized             100,000 100,000 100,000  
Aggregate of common and preferred stock, shares authorized             112,600,000   112,600,000  
Reverse stock split     14-for-1 reverse stock split              
Stock issued during period split stock     14 56,982,418            
Stock issued during period reverse stock split     14 4,070,172            
Class of warrant or right, outstanding       2,400,000            
Share-based compensation arrangement by share-based payment award, options, outstanding, number, ending balance       200,000            
Aspire Purchase Agreement [Member]                    
Fair value of common stock issued as equity issuance costs and charged against paid in capital           $ 450,000        
ATM Agreement [Member]                    
Aggregate offering price         $ 25,000,000          
Stock issued during period, shares, new issues             457,070   1,784,396  
Proceeds from issuance of common stock             $ 1,200,000   $ 12,800,000  
Aspire Purchase Agreement [Member]                    
Aggregate offering price, additions   $ 15,000,000                
Aggregate offering price, term   24 months                
Aggregate offering price, description   The lowest sale price of the Company's common stock on the purchase date; or the arithmetic average of the three (3) lowest closing sale prices for the Company's common stock during the ten (10) consecutive trading days ending on the trading day immediately preceding the purchase date.                
Maximum number of shares purchased per business day   100,000                
Aggregate offering price   $ 15,000,000                
Aspire purchase agreement, terms   In addition, on any date on which the Company submits a Purchase Notice to Aspire Capital in an amount equal to at least 100,000 shares, the Company also has the right, in its sole discretion, to present Aspire Capital with a volume-weighted average price purchase notice (each, a "VWAP Purchase Notice") directing Aspire Capital to purchase an amount of stock equal to up to 30% of the aggregate shares of the Company's common stock traded on its principal market on the next trading day (the "VWAP Purchase Date"), subject to a maximum number of shares the Company may determine. The purchase price per share pursuant to such VWAP Purchase Notice is generally 97% of the volume-weighted average price for the Company's common stock traded on its principal market on the VWAP Purchase Date.                
Maximum number of shares purchased per business day, additional   2,000,000                
Stock issued during period, shares, new issues   164,835                
Purchase Agreement [Member]                    
Stock issued during period, shares, new issues             600,000 100,000    
Proceeds from issuance of common stock             $ 1,300,000 $ 200,000    
Aggregate value available for issuance             $ 12,900,000   12,900,000  
Purchase Agreement [Member] | May 14, 2019 [Member]                    
Stock issued during period, shares, new issues             700,000      
Proceeds from issuance of common stock             $ 1,500,000      
Capital on DemandTM Sales Agreement [Member]                    
Aggregate offering price, description (i) the sale of all shares of our common stock subject to the Sales Agreement, and (ii) the termination of the Capital on Demand Agreement by JonesTrading or Celsion. The Capital on Demand Agreement may be terminated by JonesTrading or the Company at any time upon 10 days' notice to the other party, or by JonesTrading at any time in certain circumstances, including the occurrence of a material adverse change in the Company.                  
Aggregate offering price $ 16,000,000                  
Commission percentage for gross proceeds from common stock 3.00%                  
Capital on Demand Agreement [Member]                    
Stock issued during period, shares, new issues             122,186      
Proceeds from issuance of common stock             $ 300,000      
Aggregate value available for issuance             $ 15,700,000   $ 15,700,000  
Capital on Demand Agreement [Member] | May 14, 2019 [Member]                    
Stock issued during period, shares, new issues             120,700      
Proceeds from issuance of common stock             $ 300,000      
Reduction in Warrant [Member]                    
Class of warrant or right, outstanding       33,500,000            
Share-based compensation arrangement by share-based payment award, options, outstanding, number, ending balance       2,400,000