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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
3 Months Ended
Mar. 31, 2019
Mar. 31, 2018
Cash flows from operating activities:    
Net loss $ (2,367,452) $ (4,476,995)
Non-cash items included in net loss:    
Depreciation and amortization 188,806 87,171
Change in fair value of earn-out milestone liability (3,130,000) 270,195
Fair value of warrants issued in connection with amendment to modify the GEN-1 earn-out milestone payments 400,000
Recognition of deferred revenue (125,000) (125,000)
Stock-based compensation costs 691,145 153,668
Shares issued in exchange for services 15,840
Amortization of deferred finance charges and debt discount associated with notes payable 97,458
Change in deferred rent liability (1,478)
Net changes in:    
Accrued interest on investment securities (9,761) (12,752)
Advances, deposits and other current assets (645,864)
Accounts payable and accrued liabilities (635,190) (565,945)
Net cash (used in) operating activities: (5,535,858) (4,655,296)
Cash flows from investing activities:    
Purchases of investment securities (11,251,818) (5,710,392)
Proceeds from sale and maturity of investment securities 5,400,000
Purchases of property and equipment (145,162) (29,637)
Net cash (used in) provided by investing activities (5,996,980) (5,740,029)
Cash flows from financing activities:    
Proceeds from sale of common stock equity, net of issuance costs 1,754,885 1,236,584
Net cash provided by financing activities 1,754,885 1,236,584
Decrease increase in cash and cash equivalents (9,777,953) (9,158,741)
Cash and cash equivalents at beginning of period 13,353,543 11,444,055
Cash and cash equivalents at end of period 3,575,590 2,285,314
Supplemental disclosures of cash flow information:    
Interest paid 253,289
Non-cash financing and investing activities    
Fair value of warrants issued in connection with amendment to modify the GEN-1 earn-out milestone payments 400,000
Realized and unrealized gains and losses, net, on investment securities $ 56,952 $ (23,250)