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Stock-Based Compensation (Details Narrative) - USD ($) |  |  | 3 Months Ended | 6 Months Ended |
--- | --- | --- | --- | --- | ---
Feb. 19, 2019 | Sep. 28, 2018 | Jun. 30, 2019 | Jun. 30, 2018 | Jun. 30, 2019 | Jun. 30, 2018 | Dec. 31, 2018
Unrecognized compensation cost related to non-vested stock based compensation |  |  | $ 2,300,000 |  | $ 2,300,000 |  |
Stock based compensation cost expected to be recognized, weighted average period |  |  |  |  | 1 year 6 months |  |
Weighted average grant date fair value of stock option awards granted |  |  |  |  | $ 1.88 | $ 2.23 |
Research and Development Expense [Member] |  |  |  |  |  |  |
Compensation cost |  |  | 239,407 | $ 1,056,866 | $ 479,794 | $ 1,109,188 |
General and Administrative Expenses [Member] |  |  |  |  |  |  |
Compensation cost |  |  | 383,290 | 2,160,767 |  |  |
General and Administrative Expense [Member] |  |  |  |  |  |  |
Compensation cost |  |  |  |  | 834,048 | 2,277,953 |
Restricted Stock Awards [Member] |  |  |  |  |  |  |
Compensation cost |  |  | $ 3,217,633 | 3,217,633 | $ 3,387,141 | 3,387,141 |
Weighted average grant date fair value of stock option awards granted |  |  |  |  | $ 2.17 |  |
Equity Stock Awards [Member] |  |  |  |  |  |  |
Number of shares reserved for future issuance |  |  | 4,582,893 |  | 4,582,893 |  |
Inducement Awards [Member] |  |  |  |  |  |  |
Number of equity awards available for future issuance |  |  | 259,506 |  | 259,506 |  |
Stock Options [Member] |  |  |  |  |  |  |
Inducement option grant, exercise price per share |  |  |  |  | $ 2.16 |  |
Number of shares reserved for future issuance |  |  | 3,942,392 |  | 3,942,392 |  | 3,148,743
Compensation cost |  |  | $ 622,697 | $ 622,697 | $ 1,313,842 | $ 1,313,842 |
2018 Stock Incentive Plan [Member] |  |  |  |  |  |  |
Equity awards, number of stock authorized |  |  | 2,700,000 |  | 2,700,000 |  |
Percentage of fair market value of shares |  |  | 100.00% |  | 100.00% |  |
Percentage of outstanding stock determining factor for incentive stock price |  |  | 10.00% |  | 10.00% |  |
Number of shares reserved for future issuance |  |  | 3,710,386 |  | 3,710,386 |  |
2018 Stock Incentive Plan [Member] | Minimum [Member] |  |  |  |  |  |  |
Number of equity awards available for future issuance |  |  | 1,200,000 |  | 1,200,000 |  |
Percentage of fair market value of shares |  |  | 110.00% |  | 110.00% |  |
2018 Stock Incentive Plan [Member] | Maximum [Member] |  |  |  |  |  |  |
Number of equity awards available for future issuance |  |  | 3,900,000 |  | 3,900,000 |  |
2007 Stock Incentive Plan [Member] |  |  |  |  |  |  |
Equity awards, number of stock authorized |  |  | 688,531 |  | 688,531 |  |
Number of shares reserved for future issuance |  |  | 872,507 |  | 872,507 |  |
Inducement Option Grants [Member] | Five New Employees [Member] |  |  |  |  |  |  |
Inducement option grant, exercise price per share | $ 2.18 | $ 2.77 |  |  |  |  |
Option vested period | 3 years | 3 years |  |  |  |  |
Options expiration period | 10 years | 10 years |  |  |  |  |
Inducement Option Grants [Member] | Five New Employees [Member] | Restricted Stock Awards [Member] |  |  |  |  |  |  |
Shares issued | 13,000 | 19,000 |  |  |  |  |
Inducement Option Grants [Member] | Five New Employees [Member] | Common Stock [Member] |  |  |  |  |  |  |
Shares issued | 140,004 | 164,004 |  |  |  |  |

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