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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
3 Months Ended 6 Months Ended 12 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Jun. 30, 2019
Jun. 30, 2018
Dec. 31, 2018
Cash flows from operating activities:          
Net loss $ (5,904,515) $ (8,230,556) $ (8,271,967) $ (12,707,551)  
Adjustments to reconcile net loss to net cash from operating activities;          
Depreciation and amortization     362,027 174,342  
Change in fair value of earn-out milestone liability     (3,002,939) 547,324  
Fair value of warrants issued in connection with amendment to modify the GEN-1 earn-out milestone payments 400,000  
Recognition of deferred revenue     (250,000) (250,000)  
Stock-based compensation costs     1,308,492 3,371,301  
Shares issued in exchange for services     5,350 29,841  
Amortization of deferred finance charges and debt discount associated with notes payable     191,724 4,237  
Change in deferred rent liability     (2,955)  
Net changes in:          
Accrued interest on investment securities     2,636 (2,392)  
Advances, deposits and other current assets     (931,654) (62,000)  
Accounts payable and accrued liabilities     24,460 35,776  
Net cash (used in) operating activities:     (10,161,871) (8,862,077)  
Cash flows from investing activities:          
Purchases of investment securities     (13,279,686) (5,712,170)  
Proceeds from sale and maturity of investment securities     11,900,000 5,000,000  
Purchases of property and equipment     (262,728) (77,698)  
Net cash used in investing activities     (1,642,414) (789,868)  
Cash flows from financing activities:          
Proceeds from sale of common stock equity, net of issuance costs     4,464,060 1,236,584  
Proceeds received from notes payable     9,725,000  
Net cash provided by financing activities     4,464,060 10,961,584  
(Decrease) increase in cash and cash equivalents     (7,340,225) 1,309,639  
Cash and cash equivalents at beginning of period     13,353,543 11,444,055 $ 11,444,055
Cash and cash equivalents at end of period 6,013,318 12,753,694 6,013,318 12,753,694 $ 13,353,543
Supplemental disclosures of cash flow information:          
Interest paid     508,471 10,794  
Cash paid for amounts included in measurement of lease liabilities:          
Operating cash flows from lease payments 118,415 111,662 224,585  
Non-cash financing and investing activities          
Fair value of warrants issued in connection with amendment to modify the GEN-1 earn-out milestone payments     400,000  
Fair value of warrants issued in connection with the debt facility     507,116  
Right of use assets obtained in exchange for lease liabilities          
Operating leases     1,797,561  
Realized and unrealized gains and losses, net, on investment securities $ 7,752 $ 29,167 $ 64,704 $ 5,917