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Condensed Consolidated Statements of Changes in Stockholders Equity (Unaudited) - USD ($)
Common Stock [Member]
Additional Paid in Capital [Member]
Treasury Stock [Member]
Accumulated Other Comprehensive Income [Member]
Accumulated Deficit [Member]
Total
Balance at Dec. 31, 2017 $ 172,772 $ 288,408,976 $ (85,188) $ (10,164) $ (261,781,888) $ 26,704,508
Balance, shares at Dec. 31, 2017 17,276,965   334      
Net loss (12,707,551) (12,707,551)
Sale of equity through ATM purchase agreement $ 4,571 1,232,013   1,236,584
Sale of equity through ATM purchase agreement, shares 457,070          
Warrants issued in connection with debt facility   507,116       507,116
Realized and unrealized gains and losses, net, on investments securities 5,917 5,917
Stock-based compensation expense 3,371,301 3,371,301
Issuance of restricted stock $ 123 29,718 29,841
Issuance of restricted stock, shares 12,250          
Balance at Jun. 30, 2018 $ 177,466 293,549,124 $ (85,188) (4,247) (274,489,439) 19,147,716
Balance, shares at Jun. 30, 2018 17,746,285   334      
Balance at Mar. 31, 2018 $ 177,403 289,810,437 $ (85,188) (33,414) (266,258,883) 23,610,355
Balance, shares at Mar. 31, 2018 17,740,035   334      
Net loss         (8,230,556) (8,230,556)
Warrants issued in connection with debt facility   507,116       507,116
Realized and unrealized gains and losses, net, on investments securities       29,167   29,167
Stock-based compensation expense   3,217,633       3,217,633
Issuance of restricted stock $ 63 13,938       14,001
Issuance of restricted stock, shares 6,250          
Balance at Jun. 30, 2018 $ 177,466 293,549,124 $ (85,188) (4,247) (274,489,439) 19,147,716
Balance, shares at Jun. 30, 2018 17,746,285   334      
Balance at Dec. 31, 2018 $ 188,322 294,393,313 $ (85,188) 29,872 (273,665,247) 20,861,072
Balance, shares at Dec. 31, 2018 18,831,834   334      
Net loss (8,271,967) (8,271,967)
Realized and unrealized gains and losses, net, on investments securities 64,704 64,704
Stock-based compensation expense 1,308,492 1,308,492
Issuance of restricted stock $ 105 5,245 5,350
Issuance of restricted stock, shares 10,500          
Sale of equity through equity financing facilities $ 21,599 4,442,461 4,464,060
Sale of equity through equity financing facilities, shares 2,159,961          
Common stock warrants issued in connection with amendment to modify GEN-1 earn-out milestone payments 400,000 400,000
Balance at Jun. 30, 2019 $ 210,026 300,549,511 $ (85,188) 94,576 (281,937,214) 18,831,711
Balance, shares at Jun. 30, 2019 21,002,295   334      
Balance at Mar. 31, 2019 $ 196,624 297,231,041 $ (85,188) 86,824 (276,032,699) 21,396,602
Balance, shares at Mar. 31, 2019 19,662,020   334      
Net loss         (5,904,515) (5,904,515)
Realized and unrealized gains and losses, net, on investments securities       7,752   7,752
Stock-based compensation expense   617,347       617,347
Issuance of restricted stock $ 24 5,325       5,349
Issuance of restricted stock, shares 2,500          
Sale of equity through equity financing facilities $ 13,378 2,695,798       2,709,176
Sale of equity through equity financing facilities, shares 1,337,775          
Balance at Jun. 30, 2019 $ 210,026 $ 300,549,511 $ (85,188) $ 94,576 $ (281,937,214) $ 18,831,711
Balance, shares at Jun. 30, 2019 21,002,295   334