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Condensed Consolidated Statements of Changes in Stockholders' Equity (Unaudited) - USD ($)
Common Stock [Member]
Additional Paid in Capital [Member]
Treasury Stock [Member]
Accumulated Other Comprehensive Income [Member]
Accumulated Deficit [Member]
Total
Balance at Dec. 31, 2017 $ 172,772 $ 288,408,976 $ (85,188) $ (10,164) $ (261,781,888) $ 26,704,508
Balance, shares at Dec. 31, 2017 17,276,965   334      
Net loss (17,363,937) (17,363,937)
Sale of equity through ATM purchase agreement $ 4,571 1,232,013 1,236,584
Sale of equity through ATM purchase agreement, shares 457,070          
Common stock and warrants to purchase common stock issued in connection with equity and debt facilities $ 1,648 505,468 507,116
Common stock and warrants to purchase common stock issued in connection with equity and debt facilities, shares 164,835          
Realized and unrealized gains and losses, net, on investments securities 31,124 31,124
Stock-based compensation expense 3,985,829 3,985,829
Issuance of restricted stock $ 123 29,718 29,841
Issuance of restricted stock, shares 12,250          
Balance at Sep. 30, 2018 $ 179,114 294,162,004 $ (85,188) 20,960 (279,145,825) 15,131,065
Balance, shares at Sep. 30, 2018 17,911,120   334      
Balance at Jun. 30, 2018 $ 177,466 293,549,124 $ (85,188) (4,247) (274,489,439) 19,147,716
Balance, shares at Jun. 30, 2018 17,746,285   334      
Net loss (4,656,386) (4,656,386)
Common stock issued in connection with equity facilities $ 1,648 (1,648)
Common stock issued in connection with equity facilities, shares 164,835          
Realized and unrealized gains and losses, net, on investments securities 25,207 25,207
Stock-based compensation expense 614,528 614,528
Balance at Sep. 30, 2018 $ 179,114 294,162,004 $ (85,188) 20,960 (279,145,825) 15,131,065
Balance, shares at Sep. 30, 2018 17,911,120   334      
Balance at Dec. 31, 2018 $ 188,322 294,393,313 $ (85,188) 29,872 (273,665,247) 20,861,072
Balance, shares at Dec. 31, 2018 18,831,834   334      
Net loss (13,748,774) (13,748,774)
Realized and unrealized gains and losses, net, on investments securities 4,203 4,203
Stock-based compensation expense 1,762,172 1,762,172
Issuance of restricted stock $ 255 5,095 5,350
Issuance of restricted stock, shares 25,500          
Sale of equity through equity financing facilities $ 31,451 6,144,076 6,175,527
Sale of equity through equity financing facilities, shares 3,145,084          
Common stock warrants issued in connection with amendment to modify GEN-1 earn-out milestone payments 400,000 400,000
Balance at Sep. 30, 2019 $ 220,028 302,704,656 $ (85,188) 34,075 (287,414,021) 15,459,550
Balance, shares at Sep. 30, 2019 22,002,418   334      
Balance at Jun. 30, 2019 $ 210,026 300,549,511 $ (85,188) 94,576 (281,937,214) 18,831,711
Balance, shares at Jun. 30, 2019 21,002,295   334      
Net loss (5,476,807) (5,476,807)
Realized and unrealized gains and losses, net, on investments securities (60,501) (60,501)
Stock-based compensation expense 453,680 453,680
Issuance of restricted stock $ 150 (150)
Issuance of restricted stock, shares 15,000          
Sale of equity through equity financing facilities $ 9,852 1,701,615 1,711,467
Sale of equity through equity financing facilities, shares 985,123          
Balance at Sep. 30, 2019 $ 220,028 $ 302,704,656 $ (85,188) $ 34,075 $ (287,414,021) $ 15,459,550
Balance, shares at Sep. 30, 2019 22,002,418   334