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v3.20.1

Consolidated Statements of Cash Flows - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2019 | Dec. 31, 2018
Cash flows from operating activities: |  |
Net loss | $ (16,851,533) | $ (11,883,359)
Adjustments to reconcile net loss to net cash from operating activities: |  |
Depreciation and amortization | 721,665 | 356,859
Change in fair value of earn-out milestone liability | (3,189,955) | (3,630,861)
Fair value of warrants issued in connection with amendment to modify the GEN-1 earn-out milestone payments | 400,000 |
Stock-based compensation | 2,286,388 | 4,604,415
Shares issues in upon vesting of stock awards | 5,350 |
Deferred income tax asset | (1,819,324) |
Shares issued in exchange for services |  | 29,841
Impairment of in-process research and development |  | 4,510,000
Amortization of deferred finance charges and debt discount associated with note payable | 386,640 | 199,153
Change in deferred rent liability |  | (8,432)
Net changes in: |  |
Interest receivable on investments | 46,940 | (13,869)
Advances and deposits on clinical programs and other current assets | (901,377) | (362,107)
Other assets | (74,341) | (250,172)
Accounts payable - trade | (157,689) | (396,225)
Deferred revenue | (500,000) | (500,000)
Other accrued liabilities | (611,746) | 303,071
Net cash used in operating activities | (20,258,982) | (7,041,686)
Cash flows from investing activities: |  |
Purchases of investment in debt securities | (23,829,982) | (16,973,942)
Proceeds from sale and maturity of investment in debt securities | 30,115,000 | 15,480,000
Purchases of property and equipment | (349,158) | (138,399)
Net cash provided by (used in) investing activities | 5,935,860 | (1,632,341)
Cash flows from financing activities: |  |
Proceeds from issuance of common stock equity, net of issuance costs | 7,844,852 | 858,515
Proceeds from note payable, net of issuance costs |  | 9,725,000
Net cash provided by financing activities | 7,844,852 | 10,583,515
(Decrease) Increase in cash and cash equivalents | (6,478,270) | 1,909,488
Cash and cash equivalents at beginning of period | 13,353,543 | 11,444,055
Cash and cash equivalents at end of period | 6,875,273 | 13,353,543
Cash (paid for) received from: |  |
Interest | (760,615) | (512,872)
Income tax benefit |  | 10,419,115
Cash paid for amounts included in measurement of lease liabilities: |  |
Operating cash flows from lease payments | 485,848 |
Non-cash financing and investing activities |  |
Fair value of warrants issued in connection with amendment to modify the GEN-1 earn-out milestone payments | 400,000 |
Fair value of common stock issued as equity issuance costs and charged against paid in capital |  | 450,000
Fair value of warrants issued in connection with the debt facility |  | 507,116
Fair value of stock issued in exchange for cancelation of warrants |  | 8,207
Right of use assets obtained in exchange for lease liabilities |  |
Operating leases | 1,797,561 |
Realized and unrealized gains and losses, net, on investment in debt securities | $ 12,906 | $ 40,036

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