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v3.20.1

Consolidated Statements of Changes in Stockholders' Equity - USD ($) | Common Stock [Member] | Additional Paid in Capital [Member] | Treasury Stock [Member] | Accumulated Other Comprehensive Income [Member] | Accumulated Deficit [Member] | Total
--- | --- | --- | --- | --- | --- | ---
Balance at Dec. 31, 2017 | $ 172,772 | $ 288,408,976 | $ (85,188) | $ (10,164) | $ (261,781,888) | $ 26,704,508
Balance, shares at Dec. 31, 2017 | 17,276,965 |  | 334 |  |  |
Net loss |  |  |  |  | (11,883,359) | (11,883,359)
Sale of equity through ATM and common stock purchase agreement | $ 5,572 | 983,528 |  |  |  | 989,100
Sale of equity through ATM and common stock purchase agreement, shares | 557,070 |  |  |  |  |
Common stock issuance in exchange for cancellation of common stock warrants | $ 8,207 | (138,792) |  |  |  | (130,585)
Common stock issuance in exchange for cancellation of common stock warrants, shares | 820,714 |  |  |  |  |
Common stock and warrants to purchase common stock issued in connection with equity and debt facilities | $ 1,648 | 505,468 |  |  |  | 507,116
Common stock and warrants to purchase common stock issued in connection with equity and debt facilities, shares | 164,835 |  |  |  |  |
Realized and unrealized gains and losses, net, on investments securities |  |  |  | 40,036 |  | 40,036
Stock-based compensation expense |  | 4,604,415 |  |  |  | 4,604,415
Issuance of restricted stock | $ 123 | 29,718 |  |  |  | 29,841
Issuance of restricted stock, shares | 12,250 |  |  |  |  |
Balance at Dec. 31, 2018 | $ 188,322 | 294,393,313 | $ (85,188) | 29,872 | (273,665,247) | 20,861,072
Balance, shares at Dec. 31, 2018 | 18,831,834 |  | 334 |  |  |
Net loss |  |  |  |  | (16,851,533) | (16,851,533)
Realized and unrealized gains and losses, net, on investments securities |  |  |  | 12,906 |  | 12,906
Stock-based compensation expense |  | 2,286,388 |  |  |  | 2,286,388
Issuance of restricted stock | $ 380 | 4,970 |  |  |  | 5,350
Issuance of restricted stock, shares | 38,000 |  |  |  |  |
Sale of equity through equity financing facilities | $ 43,860 | 7,800,992 |  |  |  | 7,844,852
Sale of equity through equity financing facilities, shares | 4,385,984 |  |  |  |  |
Common stock warrants issued in connection with amendment to modify GEN-1 earn-out milestone payments |  | 400,000 |  |  |  | 400,000
Balance at Dec. 31, 2019 | $ 232,562 | $ 304,885,663 | $ (85,188) | $ 42,778 | $ (290,516,780) | $ 14,559,035
Balance, shares at Dec. 31, 2019 | 23,255,818 |  | 334 |  |  |

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