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Condensed Consolidated Statements of Changes in Stockholders' Equity (Unaudited) - USD ($)
Common Stock [Member]
Additional Paid in Capital [Member]
Treasury Stock [Member]
Accumulated Other Comprehensive Income [Member]
Accumulated Deficit [Member]
Total
Balance at Dec. 31, 2018 $ 188,322 $ 294,393,313 $ (85,188) $ 29,872 $ (273,665,247) $ 20,861,072
Balance, shares at Dec. 31, 2018 18,831,834   334      
Net loss (2,367,452) (2,367,452)
Sale of equity through equity financing facilities $ 8,222 1,746,663 1,754,885
Sale of equity through equity financing facilities, shares 822,186        
Stock-based compensation expense 691,145 691,145
Common stock warrants issued in connection with amendment to modify earn-out milestone payments 400,000 400,000
Realized and unrealized gains and losses, net, on investments securities 56,952 56,952
Issuance of restricted stock $ 80 (80)
Issuance of restricted stock, shares 8,000          
Balance at Mar. 31, 2019 $ 196,624 297,231,041 $ (85,188) 86,824 (276,032,699) 21,396,602
Balance, shares at Mar. 31, 2019 19,662,020   334      
Balance at Dec. 31, 2019 $ 232,562 304,885,663 $ (85,188) 42,778 (290,516,780) 14,559,035
Balance, shares at Dec. 31, 2019 23,255,818   334      
Net loss (5,056,878) (5,056,878)
Sale of equity through equity financing facilities $ 55,713 5,739,034 5,794,747
Sale of equity through equity financing facilities, shares 5,571,428        
Stock-based compensation expense 451,965 451,965
Issuance of restricted stock in lieu of cash bonus $ 4,299 494,333 498,632
Issuance of restricted stock in lieu of cash bonus, shares 429,855        
Realized and unrealized gains and losses, net, on investments securities (38,965) (38,965)
Balance at Mar. 31, 2020 $ 292,574 $ 311,570,995 $ (85,188) $ 3,813 $ (295,573,658) $ 16,208,536
Balance, shares at Mar. 31, 2020 29,257,101   334