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Condensed Consolidated Statements of Changes in Stockholders' Equity (Unaudited) - USD ($) | Common Stock [Member] | Additional Paid-In Capital [Member] | Treasury Stock [Member] | Accumulated Other Comprehensive Income [Member] | Accumulated Deficit [Member] | Total
--- | --- | --- | --- | --- | --- | ---
Balance at Dec. 31, 2018 | $ 188,322 | $ 294,393,313 | $ (85,188) | $ 29,872 | $ (273,665,247) | $ 20,861,072
Balance, shares at Dec. 31, 2018 | 18,831,834 |  | 334 |  |  |
Net loss |  |  |  |  | (13,748,774) | (13,748,774)
Sale of equity through equity financing facilities | $ 31,451 | 6,144,076 |  |  |  | 6,175,527
Sale of equity through equity financing facilities, shares | 3,145,084 |  |  |  |  |
Issuance of restricted stock | $ 255 | 5,095 |  |  |  | 5,350
Issuance of restricted stock, shares | 25,500 |  |  |  |  |
Common stock warrants issued in connection with amendment to modify GEN-1 earn-out milestone payments |  | 400,000 |  |  |  | 400,000
Realized and unrealized gains and losses, net, on investments securities |  |  |  | 4,203 |  | 4,203
Stock-based compensation expense |  | 1,762,172 |  |  |  | 1,762,172
Balance at Sep. 30, 2019 | $ 220,028 | 302,704,656 | $ (85,188) | 34,075 | (287,414,021) | 15,459,550
Balance, shares at Sep. 30, 2019 | 22,002,418 |  | 334 |  |  |
Balance at Dec. 31, 2018 | $ 188,322 | 294,393,313 | $ (85,188) | 29,872 | (273,665,247) | $ 20,861,072
Balance, shares at Dec. 31, 2018 | 18,831,834 |  | 334 |  |  |
Issuance of common stock upon exercise of options, shares |  |  |  |  |  |
Balance at Dec. 31, 2019 | $ 232,562 | 304,885,663 | $ (85,188) | 42,778 | (290,516,780) | $ 14,559,035
Balance, shares at Dec. 31, 2019 | 23,255,818 |  | 334 |  |  |
Balance at Jun. 30, 2019 | $ 210,026 | 300,549,511 | $ (85,188) | 94,576 | (281,937,214) | 18,831,711
Balance, shares at Jun. 30, 2019 | 21,002,295 |  | 334 |  |  |
Net loss |  |  |  |  | (5,476,807) | (5,476,807)
Sale of equity through equity financing facilities | $ 9,852 | 1,701,615 |  |  |  | 1,711,467
Sale of equity through equity financing facilities, shares | 985,123 |  |  |  |  |
Issuance of restricted stock | $ 150 | (150) |  |  |  |
Issuance of restricted stock, shares | 15,000 |  |  |  |  |
Realized and unrealized gains and losses, net, on investments securities |  |  |  | (60,501) |  | (60,501)
Stock-based compensation expense |  | 453,680 |  |  |  | 453,680
Balance at Sep. 30, 2019 | $ 220,028 | 302,704,656 | $ (85,188) | 34,075 | (287,414,021) | 15,459,550
Balance, shares at Sep. 30, 2019 | 22,002,418 |  | 334 |  |  |
Balance at Dec. 31, 2019 | $ 232,562 | 304,885,663 | $ (85,188) | 42,778 | (290,516,780) | 14,559,035
Balance, shares at Dec. 31, 2019 | 23,255,818 |  | 334 |  |  |
Net loss |  |  |  |  | (18,471,409) | (18,471,409)
Sale of equity through equity financing facilities | $ 123,301 | 20,127,125 |  |  |  | 20,250,426
Sale of equity through equity financing facilities, shares | 12,330,243 |  |  |  |  |
Issuance of common stock upon exercise of options | $ 1,409 | 370,486 |  |  |  | 371,895
Issuance of common stock upon exercise of options, shares | 140,864 |  |  |  |  |
Issuance of restricted stock | $ 30 | (30) |  |  |  |
Issuance of restricted stock, shares | 3,000 |  |  |  |  |
Common stock warrants issued in connection with amendment to modify GEN-1 earn-out milestone payments |  | 44,798 |  |  |  | 44,798
Realized and unrealized gains and losses, net, on investments securities |  |  |  | (42,778) |  | (42,778)
Stock-based compensation expense |  | 1,448,202 |  |  |  | 1,448,202
Issuance of common stock in lieu of cash bonus | $ 4,299 | 494,333 |  |  |  | 498,632
Issuance of common stock in lieu of cash bonus, shares | 429,855 |  |  |  |  |
Balance at Sep. 30, 2020 | $ 361,601 | 327,370,577 | $ (85,188) |  | (308,988,189) | 18,658,801
Balance, shares at Sep. 30, 2020 | 36,159,780 |  | 334 |  |  |
Balance at Jun. 30, 2020 | $ 332,297 | 324,869,780 | $ (85,188) | 7,866 | (300,916,593) | 24,208,162
Balance, shares at Jun. 30, 2020 | 33,229,380 |  | 334 |  |  |
Net loss |  |  |  |  | (8,071,596) | (8,071,596)
Sale of equity through equity financing facilities | $ 29,274 | 2,038,553 |  |  |  | 2,067,827
Sale of equity through equity financing facilities, shares | 2,927,400 |  |  |  |  |
Issuance of restricted stock | $ 30 | (30) |  |  |  |
Issuance of restricted stock, shares | 3,000 |  |  |  |  |
Common stock warrants issued in connection with amendment to modify GEN-1 earn-out milestone payments |  | 44,798 |  |  |  | 44,798
Realized and unrealized gains and losses, net, on investments securities |  |  |  | (7,866) |  | (7,866)
Stock-based compensation expense |  | 417,476 |  |  |  | 417,476
Balance at Sep. 30, 2020 | $ 361,601 | $ 327,370,577 | $ (85,188) |  | $ (308,988,189) | $ 18,658,801
Balance, shares at Sep. 30, 2020 | 36,159,780 |  | 334 |  |  |

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