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v3.20.4

Consolidated Statements of Cash Flows - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2020 | Dec. 31, 2019
Cash flows from operating activities: |  |
Net loss | $ (21,483,561) | $ (16,851,533)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 741,524 | 721,665
Change in fair value of earn-out milestone liability | 1,300,291 | (3,189,955)
Fair value of warrants issued in connection with amendment to modify the GEN-1 earn-out milestone payments |  | 400,000
Fair value of warrants issued in exchange for services | 44,798 |
Stock-based compensation | 1,851,391 | 2,286,388
Shares issued upon vesting of stock awards |  | 5,350
Change in deferred income tax asset | (26,499) | (1,819,324)
Impairment of in-process research and development | 2,370,257 |
Amortization of deferred finance charges and debt discount associated with note payable | 447,483 | 386,640
Net changes in: |  |
Accrued interest receivable on investment securities | 21,369 | 46,940
Advances and deposits on clinical programs and other current assets | (308,025) | (901,377)
Other assets | 274,513 | (74,341)
Accounts payable - trade | (618,102) | (157,689)
Deferred revenue | (500,000) | (500,000)
Other accrued liabilities | 265,885 | (611,746)
Net cash used in operating activities | (15,618,676) | (20,258,982)
Cash flows from investing activities: |  |
Purchases of investment in debt securities | (9,956,892) | (23,829,982)
Proceeds from sale and maturity of investment in debt securities | 17,900,000 | 30,115,000
Purchases of property and equipment | (19,092) | (349,158)
Net cash provided by investing activities | 7,924,016 | 5,935,860
Cash flows from financing activities: |  |
Proceeds from issuance of common stock equity, net of issuance costs | 22,811,669 | 7,844,852
Proceeds from issuance of common stock upon exercise of stock options | 371,895 |
Payments on notes payable including end-of-term fees | (5,200,000) |
Proceeds from Paycheck Protection Program ("PPP") loans | 1,324,750 |
Repayments on PPP loans | (1,324,750) |
Net cash provided by financing activities | 17,983,564 | 7,844,852
Increase (decrease) in cash and cash equivalents | 10,288,904 | (6,478,270)
Cash and cash equivalents at beginning of year | 6,875,273 | 13,353,543
Cash and cash equivalents at end of year | 17,164,177 | 6,875,273
Cash (paid for) received from: |  |
Interest | (844,278) | (1,006,760)
Cash paid for amounts included in measurement of lease liabilities: |  |
Operating cash flows from lease payments | 525,809 | 485,848
Non-cash financing and investing activities |  |
Common stock issued to settle accrued bonuses | 498,632 |
Fair value of warrants issued in connection with the debt facility, net of cancelled warrants | 81,102 |
Realized and unrealized (gains) and losses, net, on investment in debt securities | $ (42,778) | $ 12,906

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