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Financial Condition (Details Narrative) - USD ($) |  |  | 1 Months Ended | 12 Months Ended
--- | --- | --- | --- | ---
Mar. 19, 2021 | Aug. 28, 2020 | Feb. 28, 2021 | Jan. 31, 2021 | Sep. 30, 2020 | Jun. 30, 2018 | Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019 | Dec. 31, 2018
Cumulated net losses |  |  |  |  |  |  |  | $ (312,000,341) | $ (290,516,780) |
Cash and cash equivalents |  |  |  |  |  |  |  | 17,164,177 | 6,875,273 |
Proceeds from sale of equity |  |  |  |  |  |  |  | 43,000,000 |  |
Horizon Credit Agreement [Member] | Horizon Technology Finance Corporation [Member] |  |  |  |  |  |  |  |  |  |
Proceeds from new capital |  |  |  |  |  | $ 10,000,000 |  |  |  |
Debt instrument face amount |  | $ 10,000,000 |  |  |  |  |  |  |  |
Horizon Credit Agreement [Member] | Horizon Technology Finance Corporation [Member] | London Interbank Offered Rate (LIBOR) [Member] |  |  |  |  |  |  |  |  |  |
Debt instrument, interest rate |  |  |  |  |  | 7.625% |  |  |  |
Amendment to Horizon Credit Agreement [Member] | Horizon Technology Finance Corporation [Member] |  |  |  |  |  |  |  |  |  |
Repayment of loans |  | 5,000,000 |  |  |  |  |  |  |  |
Debt instrument face amount |  | 5,000,000 |  |  |  |  |  |  |  |
Debt instrument related end term charges |  | $ 200,000 |  |  |  |  |  |  |  |
Capital on DemandTM Sales Agreement [Member] | Jones Trading Institutional Services, LLC [Member] |  |  |  |  |  |  |  |  |  |
Proceeds from new capital | $ 6,900,000 |  |  |  |  |  |  |  |  |
Debt instrument face amount |  |  |  | $ 3,500,000 |  |  |  |  |  |
Proceeds from warrant exercises |  |  |  | $ 1,500,000 |  |  |  |  |  |
New Jersey [Member] |  |  |  |  |  |  |  |  |  |
Net proceeds from sale of net operating losses |  |  |  |  | $ 2,000,000 |  |  | 1,850,000 | 13,000,000 | $ 13,000,000
Proceeds from new capital |  |  |  |  |  |  |  |  | $ 1,800,000 | $ 1,040,000
New Jersey [Member] | Maximum [Member] | LPC Purchase Agreement [Member] | Lincoln Park Capital Fund, LLC [Member] |  |  |  |  |  |  |  |  |  |
Net proceeds from sale of net operating losses |  |  |  |  |  |  |  |  |  |
Proceeds from sales of net operating losses |  |  |  |  |  |  |  | $ 1,850,000 |  |
New Jersey [Member] | Forecast [Member] | Minimum [Member] |  |  |  |  |  |  |  |  |  |
Net proceeds from sale of net operating losses |  |  |  |  |  |  | $ 15,000,000 |  |  |
New Jersey [Member] | Forecast [Member] | Maximum [Member] |  |  |  |  |  |  |  |  |  |
Net proceeds from sale of net operating losses |  |  |  |  |  |  | $ 20,000,000 |  |  |
New Jersey [Member] | Subsequent Event [Member] |  |  |  |  |  |  |  |  |  |
Net proceeds from sale of net operating losses |  |  | $ 1,850,000 |  |  |  |  |  |  |

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