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Financial Condition (Details Narrative) - USD ($)			1 Months Ended				12 Months Ended
	Mar. 19, 2021	Aug. 28, 2020	Feb. 28, 2021	Jan. 31, 2021	Sep. 30, 2020	Jun. 30, 2018	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019	Dec. 31, 2018
Cumulated net losses								$ (312,000,341)	$ (290,516,780)
Cash and cash equivalents								17,164,177	6,875,273
Proceeds from sale of equity								43,000,000
Horizon Credit Agreement [Member] | Horizon Technology Finance Corporation [Member]
Proceeds from new capital						$ 10,000,000
Debt instrument face amount		$ 10,000,000
Horizon Credit Agreement [Member] | Horizon Technology Finance Corporation [Member] | London Interbank Offered Rate (LIBOR) [Member]
Debt instrument, interest rate						7.625%
Amendment to Horizon Credit Agreement [Member] | Horizon Technology Finance Corporation [Member]
Repayment of loans		5,000,000
Debt instrument face amount		5,000,000
Debt instrument related end term charges		$ 200,000
Capital on DemandTM Sales Agreement [Member] | Jones Trading Institutional Services, LLC [Member]
Proceeds from new capital	$ 6,900,000
Debt instrument face amount				$ 3,500,000
Proceeds from warrant exercises				$ 1,500,000
New Jersey [Member]
Net proceeds from sale of net operating losses					$ 2,000,000			1,850,000	13,000,000	$ 13,000,000
Proceeds from new capital									$ 1,800,000	$ 1,040,000
New Jersey [Member] | Maximum [Member] | LPC Purchase Agreement [Member] | Lincoln Park Capital Fund, LLC [Member]
Net proceeds from sale of net operating losses
Proceeds from sales of net operating losses								$ 1,850,000
New Jersey [Member] | Forecast [Member] | Minimum [Member]
Net proceeds from sale of net operating losses							$ 15,000,000
New Jersey [Member] | Forecast [Member] | Maximum [Member]
Net proceeds from sale of net operating losses							$ 20,000,000
New Jersey [Member] | Subsequent Event [Member]
Net proceeds from sale of net operating losses			$ 1,850,000

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